Tuhin Virmani

Associate Professor

University of Arkansas for Medical Sciences

faculty

Neurology, College of Medicine

18 h-index 84 pubs 1,516 cited

Research Areas

Parkinson's Disease Mechanisms and Treatments Neurological disorders and treatments Advanced Neural Network Applications Telemedicine and Telehealth Implementation Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Gait, Balance, and Falls Prevention

Links

ORCID Lab Website UAMS TRI Profile

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OverviewAI-generated summary

Dr. Tuhin Virmani's research focuses on understanding and treating neurological disorders, with a particular emphasis on Parkinson disease and movement disorders. His work has explored the underlying neurobiological mechanisms of these conditions, including the phenomenon of freezing of gait, a common and debilitating symptom in Parkinson disease patients. Dr. Virmani has investigated the relationship between levodopa medication, gait characteristics, and non-motor symptoms in individuals with Parkinson disease.

In addition to clinical and clinicopathologic studies, Dr. Virmani is actively involved in applying advanced technologies to neurological research and patient care. His recent publications highlight the use of machine learning and artificial intelligence to analyze voice samples for the identification of Parkinson disease. He has also explored the feasibility and utility of telemedicine for research visits, particularly for individuals in medically underserved areas, and has contributed to the integration of multi-modal data for precision medicine initiatives.

Dr. Virmani's academic background includes an MD/PhD from UT Southwestern Medical School, where his doctoral research focused on synaptic communication between neurons. He completed his neurology residency at Washington University and a fellowship in Movement Disorders at Columbia University Medical Center. He has collaborated extensively with researchers at the University of Arkansas for Medical Sciences, including Lakshmi Pillai, Aliyah Glover, Linda Larson‐Prior, and Aaron S. Kemp.

Research Overview

Dr. Virmani completed his medical training at UT Southwestern Medical School in Dallas where he was in the Medical Scientist Training Program (MSTP) receiving a combined M.D/Ph.D degree. His research in basic neuroscience explored the physiologic mechanisms by which neurons in the brain communicate with one other using chemical neurotransmitters at the synapse. He then went on to pursue a residency in Neurology at Washington University in St. Louis where he developed an interest in Movement Disorders. This lead to a two year combined clinical-research fellowship in Movement Disorders under the guidance of Dr. Stanley Fahn and other members of the Center for Parkinson Disease and other Movement Disorders at Columbia University Medical Center in New York. While at Columbia University, Dr. Virmani became interested in the principles underlying the phenomenon of freezing of gait in Parkinson disease and he undertook a clinicopathologic study under the mentorship of Dr. Fahn and Dr. Jean-Paul Vonsattel (Department of Pathology). He also worked with Dr. Fahn to start a clinical trial using a novel motor-neuronotrophic factor for potential neuroprotection in Parkinson disease. This trial is currently underway. In addition to his clinical duties as the Director of the Movement Disorders program at UAMS, Dr. Virmani plans to continue to develop his research interests with the establishment of a gait lab and eventual participation in national clinical research trials.

Metrics

  • h-index: 18
  • Publications: 84
  • Citations: 1,516

Selected Publications

  • Voice and Speech in Atypical Parkinsonian Disorders (2026) DOI
  • An updated definition of freezing of gait (2026) DOI
  • Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease (2025) DOI
  • A Qualitative Approach to Extract Diagnostic Patterns of Cognitive Impairment in Parkinson’s Disease (2025) DOI
  • Exploring the relationship between orthostatic hypotension and gait in people with Parkinson’s disease (2025) DOI
  • Longitudinal Monitoring of Digitized Cursive Writing in People with Parkinson’s Disease Shows Increased Variability in Absolute Jerk and Decreased Writing Duration in Those with Freezing of Gait (P9-5.019) (2025) DOI
  • Pre-trained convolutional neural networks identify Parkinson’s disease from spectrogram images of voice samples (2025) DOI
  • Pre-trained Convolutional Neural Networks Identify Parkinson’s Disease from Spectrogram Images of Voice Samples (2024) DOI
  • Levodopa influence on turning dynamics in people with Parkinson’s disease (2024) DOI
  • Feasibility of regional center telehealth visits utilizing a rural research network in people with Parkinson’s disease (2024) DOI
  • Radiofrequency ablation for patients with lumbar spinal arthritis provides quantifiable improvement in gait velocity: a prospective study (2024) DOI
  • Development and implementation of the frog-in-maze game to study upper limb movement in people with Parkinson’s disease (2023) DOI
  • A machine learning method to process voice samples for identification of Parkinson’s disease (2023) DOI
  • A Machine Learning Method to Process Voice Samples for Identification of Parkinson’s Disease (2023) DOI
  • Gait Declines Differentially in, and Improves Prediction of, People with Parkinson’s Disease Converting to a Freezing of Gait Phenotype (2023) DOI

Grants & Funding

  • Gut-microbiota-metabolite cross-talk in neuropsychiatric symptoms of Parkinson's Disease UAMS Principal Investigator
  • TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine NIH Co-Investigator
  • Gait Physiology as a non-invasive biomarker for Freezing of Gait in Parkinson’s Disease UAMS Principal Investigator
  • Machine Learning Approaches for Remote Pathological Speech Assessment for Parkinson’s Disease NSF/EPSCoR Co-Investigator
  • Comparison of different health care delivery methods in a rural underserved population of People with Parkinson’s Disease NIH/NCATS Principal Investigator
  • Utilization of a Neuroinformatics Research Platform (ARIES) to Develop Quantitative Tools for Clinical Assessment and Treatment of Parkinson’s Disease Patients in Rural Arkansas NIH/NCATS UL1TR003107 Principal Investigator
  • Gamified quantification of normal and pathological movement using 2D and Virtual Reality and Haptic sensing for therapeutic efficacy and disease progression in movement disorders NIH/NCATS Co-Investigator
  • ABI C. OBrien NIH COBRE FY26 Y4 State of Arkansas Principal Investigator

Collaborators

Researchers in the database who share publications

Lakshmi Pillai University of Arkansas for Medical Sciences 30 shared publications Aliyah Glover University of Arkansas for Medical Sciences 23 shared publications Linda Larson‐Prior University of Arkansas for Medical Sciences 17 shared publications Aaron S. Kemp University of Arkansas for Medical Sciences 13 shared publications Fred Prior University of Arkansas for Medical Sciences 6 shared publications Horace J. Spencer University of Arkansas for Medical Sciences 6 shared publications Rohit Dhall University of Arkansas for Medical Sciences 5 shared publications Yasir Rahmatallah University of Arkansas for Medical Sciences 5 shared publications

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