Sandra T. Cooper

OverviewAI-generated summary

Sandra T. Cooper's research program focuses on the application of genomic sequencing and analysis to diagnose rare and complex diseases, particularly in the areas of neurodevelopmental disorders, skeletal muscle myopathies, and perinatal conditions. Her work investigates the precise nature of variant-associated mis-splicing and the role of both biallelic and monoallelic variants in genetic disorders.

Cooper has published on the use of whole-genome sequencing (WGS) and RNA studies to identify noncoding variants in genes like *DMD* and has explored the empirical prediction of variant-activated cryptic splice donors using RNA-Seq data. Her research also extends to identifying underlying causes of pregnancy loss and perinatal death through genomic autopsy. She leads a research group and collaborates with colleagues at the University of Arkansas for Medical Sciences, including Mohammed S. Orloff, Dina M. Jones, Sandilyn Bullock, and Wonda Miller, with whom she has co-authored multiple publications.

With a career total of 155 publications and over 6,925 citations, Cooper has an h-index of 48, designating her as a highly cited researcher. Her recent work in 2023 and 2024 highlights her continued activity and contributions to the field of human genetics and rare disease diagnostics.

Metrics

• h-index: 48
• Publications: 155
• Citations: 6,925