Cancer Genomics And Diagnostics
89 researchers across 10 institutions
Cancer genomics and diagnostics research investigates the molecular underpinnings of cancer development, progression, and response to therapy. Researchers employ advanced genomic technologies, such as next-generation sequencing and single-cell analysis, to identify genetic mutations, epigenetic alterations, and gene expression patterns associated with various cancer types. This work includes characterizing tumor heterogeneity, understanding the mechanisms of drug resistance, and developing novel diagnostic and prognostic biomarkers. Computational approaches, including bioinformatics and machine learning, are integral to analyzing large-scale genomic datasets and translating findings into clinical applications.
This research holds significant relevance for Arkansas, a state facing a substantial cancer burden. Understanding the specific genetic profiles of cancers prevalent in the region can inform targeted prevention strategies and improve early detection efforts, potentially reducing mortality rates. The development of new diagnostic tools and personalized treatment approaches contributes to the growth of the state's biotechnology and healthcare sectors, fostering economic development and creating specialized jobs. Furthermore, insights gained from genomic studies can inform public health initiatives aimed at addressing cancer disparities.
This area of study draws upon expertise in molecular biology, computer science, and clinical medicine. Collaboration with researchers in bioinformatics, medical imaging, and artificial intelligence enhances the scope and impact of cancer genomics and diagnostics work across multiple Arkansas institutions.
Top Researchers
| Name | Institution | h-index | Citations | Career Stage | Badges |
|---|---|---|---|---|---|
| Jian‐Min Yuan | University of Arkansas | 95 | 37,763 | High Impact | |
| David M. Parham | UAMS | 81 | 21,213 | High Impact | |
| Huixiao Hong | NCTR | 73 | 20,717 | High Impact | |
| Naveena Singh | University of Arkansas – Fort Smith | 64 | 16,943 | High Impact | |
| David N. Church | UAMS | 45 | 9,411 | High Impact | |
| Baitang Ning | NCTR | 45 | 11,288 | ||
| Christopher P. Wardell | UAMS | 37 | 7,656 | High Impact | |
| Charles M. Quick | UAMS | 35 | 3,958 | High Impact | |
| Erming Tian | UAMS | 31 | 5,413 | High Impact | |
| Hu Jin | University of Arkansas | 26 | 2,534 | Grant PI High Impact | |
| Leihong Wu | NCTR | 25 | 2,449 | High Impact | |
| Donald J. Johann | UAMS | 23 | 2,506 | Grant PI High Impact | |
| James Lindsay | University of Arkansas | 23 | 5,023 | High Impact | |
| Sara C. Shalin | UAMS | 21 | 2,406 | High Impact Grants | |
| Binsheng Gong | NCTR | 18 | 3,009 | ||
| Saradhi Mallampati | UAMS | 17 | 956 | ||
| Ruofei Du | UAMS | 15 | 802 | ||
| Jennifer Laudadio | UAMS | 15 | 1,029 | ||
| Orwa Aboud | UAMS | 12 | 562 | ||
| Roni M. Cox | UAMS | 12 | 553 |
Related Research Areas
Strategic Outlook
Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW
Top US institutions in this area
- 1 The University of Texas MD Anderson Cancer Center 6,979
- 2 Harvard University 5,365
- 3 Memorial Sloan Kettering Cancer Center 5,363
- 4 Dana-Farber Cancer Institute 4,988
- 5 Johns Hopkins University 3,641
Cross-Institution Connections
Researchers at different institutions with overlapping expertise in Cancer Genomics And Diagnostics.