Match tier Likely match
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-07

Jinshan Jin

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Also affiliated: United States Food and Drug Administration (2016–2026); Georgia State University (2012–2021)

13 h-index 25 pubs 374 cited

  • SEC Translocation Channels
  • SecA Proteins
  • Adenosine Triphosphatases
  • Bacterial Proteins
  • Enzyme Inhibitors
  • Membrane Transport Proteins
  • Drug Design
  • Rose Bengal
  • Structure-Activity Relationship
  • Anti-Bacterial Agents
  • Disinfectants
  • Anti-Infective Agents
  • Bacillus subtilis
  • Escherichia coli
  • Humans

Biography and Research Information

OverviewAI-generated summary

Jinshan Jin's research program focuses on the design, synthesis, and evaluation of novel antimicrobial agents, with a particular emphasis on targeting bacterial SecA proteins. SecA is a crucial component of the bacterial protein translocation machinery, making it a promising target for developing new antibacterial therapies. Jin has investigated various chemical scaffolds, including rose bengal analogues, triazole-pyrimidine derivatives, and thiouracils, to identify potent SecA inhibitors.

His work also extends to understanding the mechanisms of action of these inhibitors, including their differential effects on SecA-only and SecA-SecYEG protein-conducting channels. Jin has also explored the impact of environmental factors on microbial metabolomes, such as the metabolism of azo dyes by Staphylococcus aureus, and investigated the effects of smokeless tobacco on oral microbiota in a hamster model. His scholarship metrics include an h-index of 13, with 25 total publications and 374 citations.

Metrics

  • h-index: 13
  • Publications: 25
  • Citations: 374

Selected Publications

  • Evaluating the efficacy of disinfecting products against Bacillus subtilis spore using an optimized method (2026)
    Journal of Industrial Microbiology & Biotechnology DOI OpenAlex
  • Optimization of sporulation and purification methods for sporicidal efficacy assessment on Bacillus spores (2022)
    Journal of Industrial Microbiology & Biotechnology 25 citations DOI OpenAlex
  • Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes (2021)
    Research Square DOI OpenAlex
  • Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis (2021)
    Medicinal Chemistry Research 2 citations DOI OpenAlex
  • Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes (2021)
    Annals of Microbiology 7 citations DOI OpenAlex
  • Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors (2021)
    Medicinal Chemistry Research 9 citations DOI OpenAlex
  • Smokeless tobacco impacts oral microbiota in a Syrian Golden hamster cheek pouch carcinogenesis model (2018)
    Anaerobe 24 citations DOI OpenAlex
  • Mutation network-based understanding of pleiotropic and epistatic mutational behavior of Enterococcus faecalis FMN-dependent azoreductase (2017)
    Biochemistry and Biophysics Reports 4 citations DOI OpenAlex
  • Evaluation of metabolism of azo dyes and their effects onStaphylococcus aureusmetabolome (2017)
    Journal of Industrial Microbiology & Biotechnology 36 citations DOI OpenAlex
  • Effect of smokeless tobacco products on human oral bacteria growth and viability (2016)
    Anaerobe 24 citations DOI OpenAlex
  • Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram‐Negative Bacteria (2016)
    ChemMedChem 16 citations DOI OpenAlex
  • Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena (2016)
    Toxicology in Vitro 16 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

40 Collaborators 22 Institutions 7 Countries

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