Match tier Likely match
Presence Current · Arkansas
Last published 2022
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Jinshan Jin

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

Also affiliated: United States Food and Drug Administration (2016–2021); Georgia State University (2012–2021); Division of Undergraduate Education (2012); Food and Drug Administration (2021)

Faculty Researcher

13 h-index 24 pubs 372 cited

  • SEC Translocation Channels
  • SecA Proteins
  • Adenosine Triphosphatases
  • Bacterial Proteins
  • Enzyme Inhibitors
  • Membrane Transport Proteins
  • Drug Design
  • Rose Bengal
  • Structure-Activity Relationship
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Escherichia coli
  • Humans
  • Molecular Structure
  • Protein Transport

Biography and Research Information

OverviewAI-generated summary

Jinshan Jin's research focuses on the design, synthesis, and biological evaluation of novel SecA inhibitors. SecA is a key protein involved in bacterial protein translocation, and inhibiting its function can attenuate virulence and act as an antimicrobial strategy. Jin has published work detailing the development of pyrimidine analogs and thiouracil derivatives as SecA inhibitors, investigating their effectiveness against pathogens like Methicillin-resistant *Staphylococcus aureus* (MRSA) and *Bacillus anthracis*. Some of this research explores how these inhibitors can bypass bacterial efflux pumps, a common mechanism of antibiotic resistance. Additionally, Jin has investigated the optimization of sporulation and purification methods for assessing sporicidal efficacy and studied the dye-decolorizing capabilities of bacteria isolated from tattoo inks, an environment rich in azo dyes. Jin's scholarship metrics include an h-index of 13, with 24 total publications and 356 total citations.

Metrics

  • h-index: 13
  • Publications: 24
  • Citations: 372

Selected Publications

  • Optimization of sporulation and purification methods for sporicidal efficacy assessment on <i>Bacillus</i> spores (2022)
    Journal of Industrial Microbiology & Biotechnology 25 citations DOI OpenAlex
  • Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes (2021)
    Research Square DOI OpenAlex
  • Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis (2021)
    Medicinal Chemistry Research 2 citations DOI OpenAlex
  • Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes (2021)
    Annals of Microbiology 7 citations DOI OpenAlex
  • Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors (2021)
    Medicinal Chemistry Research 9 citations DOI OpenAlex
  • Smokeless tobacco impacts oral microbiota in a Syrian Golden hamster cheek pouch carcinogenesis model (2018)
    Anaerobe 24 citations DOI OpenAlex
  • Mutation network-based understanding of pleiotropic and epistatic mutational behavior of Enterococcus faecalis FMN-dependent azoreductase (2017)
    Biochemistry and Biophysics Reports 4 citations DOI OpenAlex
  • Evaluation of metabolism of azo dyes and their effects on<i>Staphylococcus aureus</i>metabolome (2017)
    Journal of Industrial Microbiology & Biotechnology 36 citations DOI OpenAlex
  • Effect of smokeless tobacco products on human oral bacteria growth and viability (2016)
    Anaerobe 23 citations DOI OpenAlex
  • Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram‐Negative Bacteria (2016)
    ChemMedChem 16 citations DOI OpenAlex
  • Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena (2016)
    Toxicology in Vitro 15 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

18 Collaborators 8 Institutions 3 Countries

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