Richard D. Beger Source Confirmed
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Branch Chief
National Center for Toxicological Research
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Biography and Research Information
OverviewAI-generated summary
Richard D. Beger's research focuses on the application of analytical chemistry techniques, particularly mass spectrometry-based untargeted metabolomics and lipidomics, within the field of regulatory toxicology and science. He has been involved in developing and refining methodologies for quality assurance and quality control in these analytical approaches, contributing to recommendations for analytical quality management and the establishment of reference materials.
His work also addresses the integration of emerging technologies into regulatory science. Beger has contributed to discussions on reporting frameworks for transcriptomics and metabolomics in regulatory toxicology, aiming to advance the use of these 'omics' technologies for predicting biological responses and informing regulatory decisions. His research network includes collaborators from the National Center for Toxicological Research, such as Lisa Pence, Amy L. Inselman, Kellie A. Woodling, and Gonçalo Gamboa da Costa.
With a career marked by significant scholarly output, Beger has authored or co-authored over 220 publications, accumulating more than 13,300 citations and an h-index of 48, designating him as a highly cited researcher. His recent publications explore topics ranging from quality control in metabolic phenotyping to the potential of metabolomics as a translational tool for precision medicine and the discovery of proteomic biomarkers.
Metrics
- h-index: 48
- Publications: 220
- Citations: 13,311
Selected Publications
- Biomarker-driven drug development for allergic diseases and asthma: An FDA public workshop (2025) DOI
- Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers (2024) DOI
- The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses (2024) DOI
- Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial (2024) DOI
- Identification of Proteomic Biomarkers of Acetaminophen-Induced Hepatotoxicity Using Stable Isotope Labeling (2024) DOI
- The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model (2024) DOI
- Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples (2023) DOI
- Metabolomics evaluation of the photochemical impact of violet-blue light (405 nm) on ex vivo platelet concentrates (2023) DOI
- Prediction and Experimental Evaluation of the hERG Blocking Potentialof Drugs Showing Clinical Signs of Cardiotoxicity (2022) DOI
- Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management (2022) DOI
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs (2022) DOI
- Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice (2022) DOI
- Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC) (2022) DOI
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy (2021) DOI
- Identification of structural factors that affect binding to cannabinoid receptor type 1 (2021) DOI
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