Biography and Research Information
OverviewAI-generated summary
Richard D. Beger's research program focuses on the application of analytical chemistry techniques, particularly metabolomics and proteomics, within the context of regulatory toxicology and precision medicine. His work investigates the development and implementation of quality assurance and quality control (QA/QC) measures for untargeted metabolic phenotyping. This includes establishing recommendations for analytical quality management and reviewing the use of reference materials for mass spectrometry-based metabolomics and lipidomics.
Beger has contributed to frameworks for reporting transcriptomics and metabolomics data in regulatory toxicology, aligning with emerging technologies in regulatory science. His research also explores the discovery of novel proteomic biomarkers for predicting kidney recovery in patients undergoing dialysis. He has published on the application of UHPLC-MS metabolomics, including tutorials on analysis types and quantification methods, and has explored metabolomics as a translational tool for precision medicine.
His collaborations include work with Lisa Pence, Amy L. Inselman, Kellie A. Woodling, and Gonçalo Gamboa da Costa, all from the National Center for Toxicological Research. Beger's scholarly output is marked by a high impact, evidenced by an h-index of 48 and over 13,000 citations across more than 200 publications.
Metrics
- h-index: 48
- Publications: 220
- Citations: 13,646
Selected Publications
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Biomarker-driven drug development for allergic diseases and asthma: An FDA public workshop (2025)
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Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers (2024)
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The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses (2024)
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Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial (2024)
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Identification of Proteomic Biomarkers of Acetaminophen-Induced Hepatotoxicity Using Stable Isotope Labeling (2024)
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The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model (2024)
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Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples (2023)
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Metabolomics evaluation of the photochemical impact of violet-blue light (405 nm) on ex vivo platelet concentrates (2023)
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Prediction and Experimental Evaluation of the hERG Blocking Potentialof Drugs Showing Clinical Signs of Cardiotoxicity (2022)
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Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management (2022)
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Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs (2022)
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Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice (2022)
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Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC) (2022)
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Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy (2021)
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Identification of structural factors that affect binding to cannabinoid receptor type 1 (2021)
Collaboration Network
Top Collaborators
- Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
- Metabolomics evaluation of the photochemical impact of violet-blue light (405 nm) on ex vivo platelet concentrates
- Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers
Showing 5 of 7 shared publications
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Table 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
Showing 5 of 6 shared publications
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Table 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
Showing 5 of 6 shared publications
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Table 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
Showing 5 of 6 shared publications
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Table 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
Showing 5 of 6 shared publications
- Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
- Untargeted metabolomics and lipidomics in COVID-19 patient plasma reveals disease severity biomarkers
- Identification of Proteomic Biomarkers of Acetaminophen-Induced Hepatotoxicity Using Stable Isotope Labeling
- Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management
- Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
- Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples
- Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial
- Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management
- Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
- Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples
- Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
- Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
- Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs
- Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management
- Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
- Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Table 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Figure 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Data from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Supplementary Table 1 from Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
- Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients
- Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy
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