Fengping Lv

Researcher

University of Arkansas for Medical Sciences

faculty

12 h-index 28 pubs 810 cited

Research Areas

Cancer Treatment and Pharmacology Protein Degradation and Inhibitors Synthesis and biological activity Cancer-related molecular mechanisms research Drug Transport and Resistance Mechanisms Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications

Links

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OverviewAI-generated summary

Fengping Lv's research focuses on the discovery and synthesis of novel small molecules for therapeutic applications, particularly in the area of cancer treatment. A recent publication details the identification of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors, involving their design, synthesis, and biological evaluation. Another study investigates the role of ubiquitination in regulating homologous recombination and therapeutic response through the degradation of TRDMT1. Lv has a publication record of 28 papers, with 810 citations and an h-index of 12. Collaborations include work with Brendan Frett at the University of Arkansas for Medical Sciences, with whom Lv shares one publication.

Metrics

h-index: 12
Publications: 28
Citations: 810

Selected Publications

Ubiquitination-mediated degradation of TRDMT1 regulates homologous recombination and therapeutic response (2021) DOI
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation (2021) DOI