Gunaganti Naresh
Postdoctoral research associate
University of Arkansas for Medical Sciences
postdoc
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Biography and Research Information
OverviewAI-generated summary
Gunaganti Naresh's research focuses on the discovery and optimization of novel drug candidates. His work has led to the identification of compounds with potent inhibitory effects against specific cancer-related targets. Notably, his publications describe the chemical optimization of a compound for Human African Trypanosomiasis drug discovery and the development of an imidazo[1,2-a]pyridine-pyridine derivative that inhibits FLT3-ITD mutations, including those resistant to existing therapies. Further research includes the discovery of an orally active selective aurora kinase B inhibitor. Naresh has a h-index of 13 with 30 publications and 558 citations. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Xiuqi Wang and Phuc Tran.
Metrics
- h-index: 13
- Publications: 30
- Citations: 558
Selected Publications
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor (2025) DOI
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L (2023) DOI
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