Biography and Research Information
OverviewAI-generated summary
Gunaganti Naresh's research focuses on the discovery and chemical optimization of novel therapeutic agents. His work has involved the development of compounds targeting specific molecular pathways implicated in disease. He has investigated potential treatments for Human African Trypanosomiasis and explored inhibitors for FLT3-ITD, including those resistant to existing therapies. His publications also detail the discovery of orally active selective aurora kinase B inhibitors.
Naresh collaborates with researchers at the University of Arkansas for Medical Sciences, including Xiuqi Wang and Phuc Tran. His scholarship metrics include an h-index of 13, with 30 total publications and 563 citations. He is actively publishing, with his most recent work in 2025.
Metrics
- h-index: 13
- Publications: 30
- Citations: 571
Selected Publications
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Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor (2025)
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An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L (2023)
Collaboration Network
Top Collaborators
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
- An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L
- Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
- Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery
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