Biography and Research Information

OverviewAI-generated summary

Cassie M. Chandler's research focuses on the neurobiological effects of substance use, particularly during adolescence. Her work investigates how early-life exposure to substances like alcohol and fentanyl influences subsequent behavior and neurochemistry. Publications examine the impact of adolescent intermittent ethanol exposure on drinking escalation, the role of the glucocorticoid receptor in fentanyl self-administration following early-life stress, and the neuroinflammatory consequences of adolescent alcohol consumption.

Her studies also explore potential pharmacological countermeasures for substance-induced effects. This includes investigating the utility of vesicular monoamine transporter-2 inhibitors to prevent methamphetamine toxicity and examining ligands targeting specific receptors, such as the α5GABAA receptor, to modulate relapse-like drinking behaviors. Chandler's work contributes to understanding the long-term consequences of substance use and identifying potential therapeutic targets. She has published 18 papers with 138 citations and an h-index of 7.

Metrics

  • h-index: 7
  • Publications: 18
  • Citations: 138

Selected Publications

  • Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats (2024) DOI
  • The effect of bethanechol on tracheobronchomalacia in infants: A retrospective cohort study (2023) DOI

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