Eric R. Siegel

High Impact

Research Associate

UAMS primary UA Little Rock NCTR

Also affiliated: Tufts University (1981); University of Maryland, Baltimore (2018); Grant Medical Center (2002); Greater Baltimore Medical Center (2018); St. Michael's Hospital (2012); Arkansas Children's Hospital (2026); University Health Network (2012); Charleston Area Medical Center (2011); Johns Hopkins University (2018); New York Hall of Science (1998); University of Arkansas Medical Center (2024); Medical Protective (2026); Cancer Institute (WIA) (2025); Princess Margaret Cancer Centre (2012); Central Arkansas Veterans Healthcare System (2001–2017); Cancer Research And Biostatistics (2005–2023); Maryland Department of Natural Resources (2007); L. A. Orbeli Institute of Physiology NAS RA (2026); Machine Science (2023); Cancer Research Center (2007); Winthrop Rockefeller Foundation (2009–2025); Hôpital d'Hautepierre (2020); Biostatistical Consulting (United States) (2005–2006); Predictive Science (United States) (2020); Arkansas Department of Agriculture (2014–2015); University of Virginia (2023); University of Brescia (2006); University of Oklahoma (2003)

Postdoc Researcher

50 h-index 426 pubs 9,931 cited

Research Areas

Biomedical Subjects

Links

ORCID Google Scholar Research Group

OverviewAI-generated summary

Eric R. Siegel's research focuses on cancer treatment and outcomes, with a particular emphasis on gynecologic malignancies and hematologic cancers. He has investigated the efficacy of various therapeutic agents, including pembrolizumab, trastuzumab, and sacituzumab govitecan-hziy, in patients with recurrent or advanced endometrial and uterine serous carcinomas. His work also extends to understanding the tumor microenvironment and identifying potential therapeutic targets in multiple myeloma and its precursor stages.

Siegel has contributed to studies evaluating novel immunotherapies, such as bispecific BCMA/CD24 CAR-T cells for multiple myeloma, and has explored dietary interventions, like methionine restriction, to enhance response to immune checkpoint inhibitors in colorectal cancer models. Additionally, his research has touched upon patient-centered outcomes, including the social needs of individuals undergoing orthopedic surgery.

With a substantial publication record (418 publications) and a high citation count (9,872 citations), Siegel is recognized as a highly cited researcher. He collaborates with several researchers at the University of Arkansas for Medical Sciences, including Simon C. Mears, Fenghuang Zhan, John D. Shaughnessy, and Guido Tricot, and leads a research group.

Metrics

h-index: 50
Publications: 426
Citations: 9,931

Selected Publications

Long-Term Follow-Up of Patients With Multiple Myeloma Treated on Earlier Total Therapy Protocols (2025)

JAMA Oncology 6 citations DOI OpenAlex
A phase 2 trial of pembrolizumab for recurrent Lynch-like versus sporadic endometrial cancers with microsatellite instability (NCT02899793): Updated survival and response analyses (2025)

2 citations DOI OpenAlex
Does Patient Health Literacy Affect Patient Reported Outcome Measure Completion Method in Orthopaedic Patients? (2025)

Geriatric Orthopaedic Surgery & Rehabilitation 6 citations DOI OpenAlex
A customized bed based stand alone array of optically pumped magnetometers for fetal magnetocardiography measurements (2025)

Scientific Reports 8 citations DOI OpenAlex
Prior exposure to belantamab mafodotin influences outcomes with idecabtagene vicleucel in patients with multiple myeloma (2025)

4 citations DOI OpenAlex
N-acetylcysteine (NAC) supplementation improves dyspnea and may normalize von Willebrand plasma levels in gynecologic patients with Post-Acute-COVID-Sequela (PASC)/Long COVID (2025)

3 citations DOI OpenAlex
Long-term follow-up of Total Therapy IV: a phase 3 clinical trial for standard-risk multiple myeloma (2024)

Blood Advances 6 citations DOI OpenAlex
Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages (2024)

Blood Cancer Journal 35 citations DOI OpenAlex
Does Body Mass Index Affect the Success of Two-Stage Management of Periprosthetic Joint Infection? (2024)

2 citations DOI OpenAlex
Younger and rural children are more likely to be hospitalized for SARS-CoV-2 infections (2024)

3 citations DOI OpenAlex
Pediatric Off-Road Vehicle Injuries (2024)

2 citations DOI OpenAlex
CB-839 induces reversible dormancy in lung tumor-cells (2024)

European Journal of Pharmacology 8 citations DOI OpenAlex
Correlating maternal and cord-blood inflammatory markers and BDNF with human fetal brain activity recorded by magnetoencephalography: An exploratory study (2024)

3 citations DOI OpenAlex
Fetal magnetocardiographic recordings with a prototype bed-based array system of optically-pumped magnetometers (2024)

Medical Engineering & Physics 9 citations DOI OpenAlex
Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix (2024)

Proceedings of the National Academy of Sciences 18 citations DOI OpenAlex