Cancer Cells And Metastasis
204 researchers across 11 institutions
Research in cancer cells and metastasis investigates the fundamental biological processes that drive cancer growth, spread, and resistance to therapy. Scientists examine the molecular and cellular mechanisms underlying tumor initiation, progression, and the complex journey of cancer cells from primary sites to distant organs. This work employs a range of techniques, including advanced microscopy, genomic and proteomic analyses, and the development of sophisticated cellular and animal models to understand how cancer cells evade detection, invade tissues, and establish secondary tumors. Key areas of focus include identifying the genetic mutations that fuel cancer, understanding the tumor microenvironment’s role in metastasis, and exploring the signaling pathways that control cell proliferation and survival.
This research holds significant relevance for Arkansas, a state with a notable cancer burden. Understanding metastasis is critical for improving cancer prevention strategies, developing more effective diagnostic tools, and designing targeted therapies that can reduce mortality rates. The work directly informs the state’s growing biomedical sector and has implications for public health initiatives aimed at addressing cancer disparities. By elucidating the specific vulnerabilities of cancer cells, this research contributes to the development of novel treatments and interventions tailored to patient populations within Arkansas and beyond.
The study of cancer cells and metastasis is inherently interdisciplinary, drawing upon expertise from molecular biology, genetics, immunology, and pharmacology. This research is conducted across multiple institutions in Arkansas, fostering collaboration and a broad base of scientific inquiry. Connections to disease mechanisms, molecular biology techniques, cancer treatment, and immune response research are central to advancing our understanding and control of cancer.
Top Researchers
| Name | Institution | h-index | Citations | Career Stage | Badges |
|---|---|---|---|---|---|
| David M. Parham | UAMS | 81 | 21,118 | High Impact | |
| Michael J. Potter | University of Arkansas | 67 | 15,471 | Postdoctoral | |
| Vladimir P. Zharov | UAMS | 55 | 12,417 | High Impact | |
| Alan J. Tackett | UAMS | 52 | 10,768 | ARA Grant PI High Impact | |
| Soheila Korourian | UAMS | 46 | 5,712 | Faculty | High Impact |
| Dan A. Dixon | UAMS | 46 | 8,586 | Faculty | High Impact |
| Shmuel Yaccoby | UAMS | 46 | 8,239 | Faculty | High Impact |
| Shi‐Ming Tu | UAMS | 45 | 8,071 | Faculty | High Impact |
| Ekaterina I. Galanzha | UAMS | 45 | 7,250 | High Impact | |
| Jingying Zhang | University of Arkansas | 42 | 6,330 | Postdoctoral | High Impact |
| Si Chen | NCTR | 40 | 4,885 | High Impact | |
| James Y. Suen | UAMS | 40 | 5,108 | Faculty | High Impact |
| Charles Matthew Quick | UAMS | 35 | 3,973 | Faculty | High Impact |
| Ren Xu | UAMS | 34 | 5,357 | Faculty | ARA Grant PI |
| Benjamin J. Swanson | University of Arkansas | 32 | 6,333 | High Impact | |
| Isabelle Racine Miousse | UAMS | 30 | 3,095 | Faculty | Grant PI High Impact |
| Magda O. El-Shenawee | University of Arkansas | 28 | 2,770 | Faculty | Grant PI High Impact |
| Zeid A. Nima | UA Little Rock | 28 | 2,166 | ||
| Michael Birrer | UAMS | 27 | 20,276 | Faculty | High Impact |
| Issam Makhoul | UAMS | 27 | 2,138 | Faculty |
Related Research Areas
Strategic Outlook
Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW
Top US institutions in this area
- 1 The University of Texas MD Anderson Cancer Center 3,994
- 2 Harvard University 3,255
- 3 National Cancer Institute 2,643
- 4 National Institutes of Health 2,256
- 5 University of Michigan 1,848
Cross-Institution Connections
Researchers at different institutions with overlapping expertise in Cancer Cells And Metastasis.