Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
J
Jeannine Marie Durdik
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Professor
Also affiliated: Tufts University (1990–1992); Johns Hopkins University (1977); University of Washington (1980); Purdue University West Lafayette (1978); MedStar Good Samaritan Hospital (1977); Fred Hutch Cancer Center (1980–1981); National Institute of Immunology (1997–2002); University of Colorado Anschutz (1994); Brandeis University (1984–2002); University of Pennsylvania (1994); University of Colorado Denver (1994)
23 h-index
64 pubs
1,835 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jeannine Marie Durdik's research program focuses on the study of immune cell function, particularly T-lymphocytes and B-lymphocytes, and their genetic regulation. Her work has investigated mechanisms of gene rearrangement in immunoglobulin light chains, including novel kappa light-chain gene rearrangements and intrachromosomal DNA recombinations in lambda light chain-producing B cells. Durdik has also explored the role of inducible nitric oxide synthase in T cells, examining its regulation of T cell death and the development of immune memory. Further research has examined T cell aging, considering its effects on T cell development, survival, and function.
Durdik's publications also include work on cell surface markers, such as the identification of ganglio-N-tetraosylceramide as a marker for murine natural killer (NK) cells, and the investigation of glycolipid expression in lymphoma cell variants and their susceptibility to NK cells. Her research has been supported by various grants, and she has collaborated with researchers at the University of Arkansas at Fayetteville. She leads a research group and has a notable publication record with an h-index of 23 and over 1,800 citations.
Metrics
- h-index: 23
- Publications: 64
- Citations: 1,835
Positions
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Professor 2004–presentUniversity of Arkansas Department of Biological Sciences ORCID
Selected Publications
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Fever temperature alters metabolic and cytokine activities in activated macrophages in mice, chickens and fish 2266416 (2026)
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Effects of fever temperatures on metabolic changes and gene expression in activated monocytic cells from mouse, chicken and rainbow trout sources (2026)
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The Effects of Fever on Macrophage Metabolism and Function in Young and Aged Cells (2023)
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Effect of temperature on functional activity of macrophages in three different species (2020)
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Febrile temperature change modulates CD4 T cell differentiation via a TRPV channel-regulated Notch-dependent pathway (2020)
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Investigation on the role of temperature in macrophage responses (2019)
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Functionally significant metabolic differences between B and T lymphocyte lineages (2019)
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Comparison of Polyvinyl Alcohol (PVA) vs Collagen Sponges to Assess Macrophage Activation Patterns in Rats (2018)
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Correlation of cell‐surface CD 8 levels with function, phenotype and transcriptome of naive CD 8 T cells (2018)
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Iloprost Affects Macrophage Activation and CCL2 Concentrations in a Microdialysis Model in Rats (2018)
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Abstract A80: Functionally significant heterogeneity in apparently homogenous naive CD8 T cell populations (2017)
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A role for MHC-mediated signalling in the functional and phenotypic heterogeneity of naive T cells (IRC8P.454) (2015)
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Effects of delayed delivery of dexamethasone-21-phosphate via subcutaneous microdialysis implants on macrophage activation in rats (2015)
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Localized delivery of dexamethasone-21-phosphate via microdialysis implants in rat induces M(GC) macrophage polarization and alters CCL2 concentrations (2014)
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Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function (2014)
Collaboration Network
Top Collaborators
Satyajit Rath
National Institute of Immunology (IN)
21 shared publications
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
- Febrile temperature change modulates CD4 T cell differentiation via a TRPV channel-regulated Notch-dependent pathway
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- Functionally significant metabolic differences between B and T lymphocyte lineages
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
Showing 5 of 21 shared publications
Anna George
National Institute of Immunology (IN)
17 shared publications
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
- Febrile temperature change modulates CD4 T cell differentiation via a TRPV channel-regulated Notch-dependent pathway
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- Functionally significant metabolic differences between B and T lymphocyte lineages
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
Showing 5 of 17 shared publications
Vineeta Bal
National Institute of Immunology (IN)
17 shared publications
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
- Febrile temperature change modulates CD4 T cell differentiation via a TRPV channel-regulated Notch-dependent pathway
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- Functionally significant metabolic differences between B and T lymphocyte lineages
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
Showing 5 of 17 shared publications
Matthew F Faulkner
University of Arkansas at Fayetteville (US)
5 shared publications
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- Increase in double-stranded DNA break-related foci in early-stage thymocytes of aged mice
- Age-associated defects in Tcell metabolism (46.10)
- Age‐related defects in T‐cell metabolism
- Enumeration of double stranded DNA breaks in developing thymocytes in young and aged mice (B1)
Hamid Mattoo
National Institute of Immunology (IN)
5 shared publications
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- A role for apoptosis-inducing factor in T cell development
- Role of apoptosis-inducing factor (Aif) in the T cell lineage.
- Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function
- A role for MHC-mediated signalling in the functional and phenotypic heterogeneity of naive T cells (IRC8P.454)
Julie A. Stenken
University of Arkansas at Fayetteville
5 shared publications
In database
- Localized delivery of dexamethasone-21-phosphate via microdialysis implants in rat induces M(GC) macrophage polarization and alters CCL2 concentrations
- Comparison of microdialysis sampling perfusion fluid components on the foreign body reaction in rat subcutaneous tissue
- Effects of delayed delivery of dexamethasone-21-phosphate via subcutaneous microdialysis implants on macrophage activation in rats
- Iloprost Affects Macrophage Activation and CCL2 Concentrations in a Microdialysis Model in Rats
- Comparison of Polyvinyl Alcohol (PVA) vs Collagen Sponges to Assess Macrophage Activation Patterns in Rats
Ranjan Sen
Brandeis University (US)
4 shared publications
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
- Commitment of Activated T Cells to Secondary Responsiveness Is Enhanced by Signals Mediated by cAMP-Dependent Protein Kinase A-I
- Presence of Pentoxifylline During T Cell Priming Increases Clonal Frequencies in Secondary Proliferative Responses and Inhibits Apoptosis
- Pentoxifylline Inhibits Ig κ Gene Transcription and Rearrangements in Pre-B Cells
Savit B. Prabhu
Christian Medical College, Vellore (IN)
4 shared publications
- Functionally significant metabolic differences between B and T lymphocyte lineages
- Role of apoptosis-inducing factor (Aif) in the T cell lineage.
- Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function
- A role for MHC-mediated signalling in the functional and phenotypic heterogeneity of naive T cells (IRC8P.454)
Monika Vig
National Institute of Immunology (IN)
4 shared publications
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
- Commitment of Activated T Cells to Secondary Responsiveness Is Enhanced by Signals Mediated by cAMP-Dependent Protein Kinase A-I
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
Smita Srivastava
National Institute of Immunology (IN)
4 shared publications
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
- Apoptosis-Inducing Factor Regulates Death in Peripheral T Cells
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
Usha Kandpal
National Institute of Immunology (IN)
4 shared publications
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death
- Inducible nitric oxide synthase in T cells regulates T cell death and immune memory
Hridesh Banerjee
National Institute of Immunology (IN)
4 shared publications
- Functionally significant metabolic differences between B and T lymphocyte lineages
- A role for apoptosis-inducing factor in T cell development
- Apoptosis-Inducing Factor Regulates Death in Peripheral T Cells
- Role of apoptosis-inducing factor (Aif) in the T cell lineage.
Jasneet Kaur Khalsa
National Institute of Immunology (IN)
4 shared publications
- Functionally significant metabolic differences between B and T lymphocyte lineages
- A role for apoptosis-inducing factor in T cell development
- Role of apoptosis-inducing factor (Aif) in the T cell lineage.
- A role for MHC-mediated signalling in the functional and phenotypic heterogeneity of naive T cells (IRC8P.454)
Sanket Rane
National Institute of Immunology (IN)
3 shared publications
- Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function
- Correlation of cell‐surface CD 8 levels with function, phenotype and transcriptome of naive CD 8 T cells
- A role for MHC-mediated signalling in the functional and phenotypic heterogeneity of naive T cells (IRC8P.454)
Rituparna Das
National Institute of Immunology (IN)
3 shared publications
- Naive CD4 T cells from aged mice show enhanced death upon primary activation
- Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function
- A role for MHC-mediated signalling in the functional and phenotypic heterogeneity of naive T cells (IRC8P.454)
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