Jeffrey C. Wolchok Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor/ DepartmentChairperson
University of Arkansas at Fayetteville
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Biography and Research Information
OverviewAI-generated summary
Jeffrey C. Wolchok's research investigates mechanisms of tissue repair and regeneration, with a particular focus on volumetric muscle loss and traumatic brain injury models. His work explores how the immune system influences recovery and how biomaterials can enhance repair processes. This includes studying the role of local delivery of immunomodulatory factors, such as IL-10, and evaluating cell-derived extracellular matrix scaffolds for their regenerative potential.
Wolchok's laboratory also examines the neurological consequences of injury, including blood-brain barrier integrity and astrocyte reactivity following repeated traumatic brain injury. His research utilizes advanced techniques, such as NADH fluorescence lifetime measurements in skeletal muscle, to gain a deeper understanding of cellular function and injury response. He has received federal funding from agencies including the NIH and NSF to support instrumentation for single-cell RNA sequencing and biofiber engineering.
His collaborations within the University of Arkansas at Fayetteville include researchers such as Tai Huynh, John Taehwan Kim, Tyrone A. Washington, and Jacob Schluns, with whom he has co-authored multiple publications. Wolchok's scholarship metrics include an h-index of 16 and over 761 citations across his 49 publications.
Metrics
- h-index: 16
- Publications: 49
- Citations: 761
Selected Publications
- Aerobic Exercise Training Does Not Attenuate Fibrosis In Autologous Repaired Vml-injured Skeletal Muscle (2025) DOI
- BOARD # 307: University of Arkansas Biomedical Engineering REU Site: Training in Emerging Biomedical Optics and Imaging Approaches (2025) DOI
- <i>In vivo</i> measurement of NADH fluorescence lifetime in skeletal muscle via fiber-coupled time-correlated single photon counting (2023) DOI
- Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss (2023) DOI
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy (2023) DOI
- Prescribing reduced physical activity following volumetric muscle loss not really a good idea (2023) DOI
- Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury (2023) DOI
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy (2023) DOI
- Delivery of a tissue derived extracellular matrix gel modulates early fibro-adipogenic cell behavior and improves recovery following both acute and chronic atrophy muscle injury (2022) DOI
- Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury (2022) DOI
- Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i> (2022) DOI
- Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury (2022) DOI
- Impact and Delivery of an Engineering Service Learning Course in a Remote Environment (2021) DOI
- Blood–Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury (2021) DOI
- The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss (2021) DOI
Federal Grants 3 $1,058,421 total
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