Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
J
Jeffrey C. Wolchok
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
Professor/ DepartmentChairperson
Also affiliated: University of Utah (2008–2010); David Grant USAF Medical Center (1998); Plano Orthopedic Sports Medicine & Spine Center (2001); University of California, Davis (1998); The University of Texas Southwestern Medical Center (2001)
17 h-index
54 pubs
803 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jeffrey C. Wolchok's research program focuses on tissue engineering, with a specific emphasis on skeletal muscle regeneration and the development of biological scaffolds. He has investigated methods for improving recovery from volumetric muscle loss injuries in animal models, comparing outcomes in young versus aged rats. His work also explores the mechanical properties of tissues, including comparative analyses of human and porcine colon tissue.
Wolchok has secured federal funding for his research, including grants from the National Institutes of Health (NIH) and the National Science Foundation (NSF). These grants support instrumentation for single-cell RNA sequencing and the engineering of cell-derived extracellular matrix (ECM) biolfibers. He also co-PI'd an NSF grant focused on training in biomedical optics and imaging.
His publications include studies on the effects of bioreactor-induced vibrational stimulation on fibroblast ECM production and the isolation of cell-derived ECM constructs using sacrificial foams. Wolchok's work contributes to the broader fields of regenerative medicine and biomaterials science. He maintains an active research group at the University of Arkansas at Fayetteville and collaborates with several colleagues within the institution.
Metrics
- h-index: 17
- Publications: 54
- Citations: 803
Positions
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Professor/ DepartmentChairperson 2024–presentUniversity of Arkansas Department of Biomedical Engineering ORCID
Selected Publications
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Biological Sex Modulates Inflammatory Gene Expression After Minced Muscle Repair And High Intensity Exercise Following Vml (2026)
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Combined High-Intensity Exercise and Autologous Muscle Grafting Differentially Modulate Myogenesis and Extracellular Matrix Remodeling by Sex in VML-Injured Muscle (2026)
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Exercise Intensities Modulates Inflammatory Gene Expression to Minced Muscle Repair Following Volumetric Muscle Loss (2026)
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Aerobic Exercise Training Does Not Attenuate Fibrosis In Autologous Repaired Vml-injured Skeletal Muscle (2025)
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BOARD # 307: University of Arkansas Biomedical Engineering REU Site: Training in Emerging Biomedical Optics and Imaging Approaches (2025)
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Board 107: Work in Progress: Development of an Innovation Corps-Modeled Bioengineering Course to Promote Entrepreneurial Engagement among Undergraduate Students. (2024)
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In vivo measurement of NADH fluorescence lifetime in skeletal muscle via fiber-coupled time-correlated single photon counting (2023)
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Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss (2023)
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Transcriptome profiling of a synergistic volumetric muscle loss repair strategy (2023)
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Prescribing reduced physical activity following volumetric muscle loss not really a good idea (2023)
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Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury (2023)
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Transcriptome profiling of a synergistic volumetric muscle loss repair strategy (2023)
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Delivery of a tissue derived extracellular matrix gel modulates early fibro-adipogenic cell behavior and improves recovery following both acute and chronic atrophy muscle injury (2022)
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Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury (2022)
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Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury In vivo (2022)
Federal Grants 3 $1,058,421 total
NIH
Contact PI
Jul 2022 - Jun 2023
NSF
PI
Aug 2023 - Jul 2027
NSF
Co-PI
May 2023 - Apr 2027
REU Site: Training in Emerging Biomedical Optics and Imaging Approaches
Collaboration Network
Top Collaborators
Tyrone A. Washington
University of Arkansas at Fayetteville
12 shared publications
In database
- Codelivery of Infusion Decellularized Skeletal Muscle with Minced Muscle Autografts Improved Recovery from Volumetric Muscle Loss Injury in a Rat Model
- Recovery from volumetric muscle loss injury: A comparison between young and aged rats
- Graft alignment impacts the regenerative response of skeletal muscle after volumetric muscle loss in a rat model
- Regenerative Repair of Volumetric Muscle Loss Injury is Sensitive to Age
- Development of an infusion bioreactor for the accelerated preparation of decellularized skeletal muscle scaffolds
Showing 5 of 12 shared publications
Kevin Roberts
University of Arkansas at Fayetteville
8 shared publications
In database
- The characterization of decellularized human skeletal muscle as a blueprint for mimetic scaffolds
- Graft alignment impacts the regenerative response of skeletal muscle after volumetric muscle loss in a rat model
- Cell derived extracellular matrix fibers synthesized using sacrificial hollow fiber membranes
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury
Showing 5 of 8 shared publications
Grady Dunlap
University of Arkansas at Fayetteville
7 shared publications
In database
- Graft alignment impacts the regenerative response of skeletal muscle after volumetric muscle loss in a rat model
- Regenerative Repair of Volumetric Muscle Loss Injury is Sensitive to Age
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury
- In vivo testing of an injectable matrix gel for the treatment of shoulder cuff muscle fatty degeneration
Showing 5 of 7 shared publications
Tai Huynh
University of Arkansas at Fayetteville
7 shared publications
In database
- Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury
- Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- In vivo testing of an injectable matrix gel for the treatment of shoulder cuff muscle fatty degeneration
- Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury
Showing 5 of 7 shared publications
Jamie Hestekin
University of Arkansas at Fayetteville
6 shared publications
In database
- Cell derived extracellular matrix fibers synthesized using sacrificial hollow fiber membranes
- Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- Production of Extracellular Matrix Fibers via Sacrificial Hollow Fiber Membrane Cell Culture
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
Showing 5 of 6 shared publications
John T. Kim
University of Arkansas at Fayetteville
5 shared publications
In database
- Recovery from volumetric muscle loss injury: A comparison between young and aged rats
- Regenerative Repair of Volumetric Muscle Loss Injury is Sensitive to Age
- Development of an infusion bioreactor for the accelerated preparation of decellularized skeletal muscle scaffolds
- The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss
- Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury
Lemuel A. Brown
University of Arkansas at Fayetteville
5 shared publications
In database
- Codelivery of Infusion Decellularized Skeletal Muscle with Minced Muscle Autografts Improved Recovery from Volumetric Muscle Loss Injury in a Rat Model
- Recovery from volumetric muscle loss injury: A comparison between young and aged rats
- Graft alignment impacts the regenerative response of skeletal muscle after volumetric muscle loss in a rat model
- Moderators of skeletal muscle maintenance are compromised in sarcopenic obese mice
- Graft Alignment Impacts the Regenerative Response of Skeletal Muscle after Volumetric Muscle Loss in a Rat Model
Kartik Balachandran
University of Arkansas at Fayetteville
5 shared publications
In database
- Acetazolamide Mitigates Astrocyte Cellular Edema Following Mild Traumatic Brain Injury
- Valve interstitial cell shape modulates cell contractility independent of cell phenotype
- Blood–Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury
- Repeated In Vitro Impact Conditioning of Astrocytes Decreases the Expression and Accumulation of Extracellular Matrix
- Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury In vivo
Jacob Schluns
University of Arkansas at Fayetteville
5 shared publications
In database
- Cell derived extracellular matrix fibers synthesized using sacrificial hollow fiber membranes
- Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- In vivo measurement of NADH fluorescence lifetime in skeletal muscle via fiber-coupled time-correlated single photon counting
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
John Taehwan Kim
University of Arkansas at Fayetteville
5 shared publications
In database
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- In vivo testing of an injectable matrix gel for the treatment of shoulder cuff muscle fatty degeneration
- Production of Extracellular Matrix Fibers via Sacrificial Hollow Fiber Membrane Cell Culture
- Transcriptome profiling of a synergistic volumetric muscle loss repair strategy
- Production of Extracellular Matrix Fibers via Sacrificial Hollow Fiber Membrane Cell Culture
Richard Perry
University of Arkansas at Fayetteville (US)
5 shared publications
- Regenerative Repair of Volumetric Muscle Loss Injury is Sensitive to Age
- Moderators of skeletal muscle maintenance are compromised in sarcopenic obese mice
- The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss
- Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury
- The Effects of Physical Activity On Force Recovery From Volumetric Muscle Loss With Autograph Incorporation
Benjamin Kasukonis
University of Arkansas at Fayetteville
4 shared publications
In database
- Codelivery of Infusion Decellularized Skeletal Muscle with Minced Muscle Autografts Improved Recovery from Volumetric Muscle Loss Injury in a Rat Model
- Recovery from volumetric muscle loss injury: A comparison between young and aged rats
- Regenerative Repair of Volumetric Muscle Loss Injury is Sensitive to Age
- Development of an infusion bioreactor for the accelerated preparation of decellularized skeletal muscle scaffolds
Timothy J. Muldoon
University of Arkansas at Fayetteville
4 shared publications
In database
- In vivo measurement of NADH fluorescence lifetime in skeletal muscle via fiber-coupled time-correlated single photon counting
- Impact and Delivery of an Engineering Service Learning Course in a Remote Environment
- Board 107: Work in Progress: Development of an Innovation Corps-Modeled Bioengineering Course to Promote Entrepreneurial Engagement among Undergraduate Students.
- BOARD # 307: University of Arkansas Biomedical Engineering REU Site: Training in Emerging Biomedical Optics and Imaging Approaches
Sepideh Shakeri
University of Arkansas at Fayetteville
4 shared publications
In database
- Aerobic Exercise Training Does Not Attenuate Fibrosis In Autologous Repaired Vml-injured Skeletal Muscle
- Exercise Intensities Modulates Inflammatory Gene Expression to Minced Muscle Repair Following Volumetric Muscle Loss
- Combined High-Intensity Exercise and Autologous Muscle Grafting Differentially Modulate Myogenesis and Extracellular Matrix Remodeling by Sex in VML-Injured Muscle
- Biological Sex Modulates Inflammatory Gene Expression After Minced Muscle Repair And High Intensity Exercise Following Vml
Joseph Wyatt
University of Arkansas at Fayetteville
3 shared publications
In database
- Repeated In Vitro Impact Conditioning of Astrocytes Decreases the Expression and Accumulation of Extracellular Matrix
- An In Vitro Impact Model for the Study of Central Nervous System Cell Mechanobiology
- Development of a Traumatic Brain Injury Bioreactor
Similar Researchers
Based on overlapping research topics
Jacob Schluns
University of Arkansas at Fayetteville
Tissue Engineering and Regenerative Medicine
Muscle Physiology and Disorders
Extracellular Matrix
Kevin W. S. Roberts
University of Arkansas at Fayetteville
Tissue Engineering and Regenerative Medicine
Muscle Physiology and Disorders
Animal, Disease Models
Tai Huynh
University of Arkansas at Fayetteville
Tissue Engineering and Regenerative Medicine
Muscle Physiology and Disorders
Extracellular Matrix
Payton Phelps
University of Arkansas at Fayetteville
Tissue Engineering and Regenerative Medicine
Muscle Physiology and Disorders
Extracellular Matrix
Bandy William
University of Central Arkansas
Muscle Physiology and Disorders
Medical Research
Biomedical and Engineering Education
John T. Kim
University of Arkansas at Fayetteville
Tissue Engineering and Regenerative Medicine
Muscle Physiology and Disorders
Extracellular Matrix