David N. Church
Assistant Professor
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
David N. Church's research focuses on the application of computational methods and molecular insights to understand and improve cancer diagnosis and treatment. He has published work examining the genomic landscape of colorectal cancers and the development of clinical decision support systems that integrate deep learning with pathological markers to optimize adjuvant chemotherapy. His investigations also extend to endometrial cancer, where he has studied the clinical and molecular correlates of p53 immunohistochemistry and the prognostic significance of tertiary lymphoid structures. Furthermore, his work addresses the broader challenges and promises of adoptive T-cell therapies for solid tumors.
With a strong publication record, including a significant number of peer-reviewed articles, Church holds an h-index of 45 and has accumulated over 9,000 citations. His recent publications span diverse areas within oncology, including the genomic underpinnings of colorectal cancers, the role of specific mutations in endometrial cancer, and the potential of advanced computational models for biomarker prediction from histological data. He actively leads a research group and collaborates with researchers at the University of Arkansas for Medical Sciences and the University of Arkansas at Fayetteville, fostering a network of shared scientific inquiry.
His work contributes to the understanding of cancer biology and the development of data-driven approaches in clinical oncology. This includes exploring signatures of mutagenesis and evaluating treatment effects in patient populations with specific genetic profiles, such as those with POLE mutations in endometrial cancer.
Metrics
- h-index: 45
- Publications: 242
- Citations: 9,411
Selected Publications
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Guidelines for replacement of a balloon gastrostomy tube in infants and pediatric patients: The American Society for Parenteral and Enteral Nutrition (2026)
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From Anecdote to Evidence: Dispelling Myths in Bodybuilding and Physique Sports (2026)
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Guidelines for nutrition in adults with head and neck cancer: The American Society for Parenteral and Enteral Nutrition (2026)
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Elevated miR-194-5p Expression during Short-Term Energy Deficit Attenuates Postexercise Muscle Protein Synthesis by Inhibiting Anabolic Signaling (2026)
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Effects of acute essential amino acid intake on post-prandial raw bioimpedance and fluid shifts between healthy young and older adults: An exploratory pilot study (2025)
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The effect of bed rest, unilateral limb immobilization and head‐down tilt on muscle protein synthesis: A systematic review and meta‐analysis (2025)
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Exploring the multifactorial causes and therapeutic strategies for anabolic resistance in sarcopenia: A systems modeling study (2025)
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The Effects of Essential Amino Acid Supplementation on Hippocampal Neurotrophin, Dopaminergic and Serotonergic Changes in an Overtraining Mouse Model (2025)
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Antiaging agents: pharmacological therapy targeted at preserving skeletal muscle size and function in aging adults (2025)
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Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond (2025)
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Effects of exercise with or without a hypocaloric diet on intermuscular and intramuscular fat: a systematic review (2025)
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Muscle Protein Synthesis Response to Whole-Foods and Free-Form Essential Amino Acids: An Exploratory Analysis (2025)
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The effect of nandrolone decanoate administration on fatigue during a volume‐overload stress in male mice (2025)
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The Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta‐Analysis (2025)
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Proximate analysis and concordance with nutritional labeling of most sold protein bars in Santiago, Chile (2025)
Grants & Funding
As listed on this researcher's institutional profile.
- Effects of lean pork loin intake and GLP-1 receptors agonist on protein homeostasis and glucose regulation in prediabetic adults National Pork Board
- Ferrando - Optimizing Performance for Soldiers II (OPS II ) Pennington/USARIEM U.S. Army Research Institute of Environmental Medicine via Pennington Biomedical Research Center
- ABI C. OBrien NIH COBRE FY26 Y4 State of Arkansas
- INVESTIGATING THE ROLE OF SERUM RESPONSE FACTOR IN CARDIAC MITOCHONDRIAL BIOENERGETICS AND FUNCTION IN THE AGING HEART National Pork Board
- Effects of lean pork on protein homeostasis and glucose regulation in prediabetic adults. National Pork Board
Collaboration Network
Top Collaborators
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- The contributory role of vascular health in age‐related anabolic resistance
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
- Whole-body protein kinetic models to quantify the anabolic response to dietary protein consumption
Showing 5 of 26 shared publications
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consideration of the role of protein quality in determining dietary protein recommendations
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
- Whole-body protein kinetic models to quantify the anabolic response to dietary protein consumption
Showing 5 of 17 shared publications
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations
- Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study
- Effects of exercise with or without a hypocaloric diet on intermuscular and intramuscular fat: a systematic review
Showing 5 of 7 shared publications
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations
- Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study
Showing 5 of 7 shared publications
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Continuous oral stable isotope ingestion to measure whole-body protein turnover
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
- 440 Muscle Protein Synthesis and Whole-Body Protein Balance Following Ingestion of Beef or a Soy Protein Based Meat Alternative
Showing 5 of 7 shared publications
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
- 440 Muscle Protein Synthesis and Whole-Body Protein Balance Following Ingestion of Beef or a Soy Protein Based Meat Alternative
- Exploratory Analysis Of Protein Metabolism Sex Difference Following Feeding
- Consideration of the role of protein quality in determining dietary protein recommendations
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
- Whole-body protein kinetic models to quantify the anabolic response to dietary protein consumption
- Muscle Protein Synthesis Response to Whole-Foods and Free-Form Essential Amino Acids: An Exploratory Analysis
- Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations
- Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study
- Testosterone Administration Does Not Affect The Muscle Metabolome During Severe Energy Deficit And Subsequent Recovery
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
- 440 Muscle Protein Synthesis and Whole-Body Protein Balance Following Ingestion of Beef or a Soy Protein Based Meat Alternative
- Exploratory Analysis Of Protein Metabolism Sex Difference Following Feeding
- Understanding Dietary Protein Quality: Digestible Indispensable Amino Acid Scores and Beyond
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
- Muscle Protein Synthesis Response to Whole-Foods and Free-Form Essential Amino Acids: An Exploratory Analysis
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
- Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study
- Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed
- Skeletal Muscle MicroRNA Are Sensitive To Energy But Not Acute Macronutrient Availability During Energy Deficit
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