Match tier
Institution-verified
Presence
Current · Arkansas
Last published
2026
Sources
Institutional record
Refreshed
2026-08-15
G
Gohar Azhar
Sourced from institutional research profiles (UAMS TRI or ARA).
High Impact
Researcher
Also affiliated: State University of Malang (2024–2025); Beth Israel Deaconess Medical Center (1997–2002); Harvard University (1996–2001); The University of Texas at San Antonio Health Science Center (2012); University of Arkansas Medical Center (2014–2026); Beth Israel Deaconess Hospital (1996–1997); Central Arkansas Veterans Healthcare System (2004–2019); Geriatric Research Education and Clinical Center (2004–2015); Institute on Aging (2010–2026); Scripps MD Anderson Cancer Center (2024); Riddet Institute (2020); Massey University (2020); Quest Diagnostics (United States) (1999)
Faculty Researcher
33 h-index
533 pubs
3,181 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Gohar Azhar's research group at the University of Arkansas for Medical Sciences investigates the molecular mechanisms underlying aging and age-related diseases. This work includes studies on mitochondrial function and its role in cellular aging, as well as the impact of oxidative stress on biological systems. Recent publications from the group have explored how specific amino acids can improve mitochondrial function and protect against oxidative damage, and how dietary supplements may enhance physical performance in older adults.
Further research extends to neuroinflammation and the effects of microbial components, such as lipopolysaccharide from *P. gingivalis*, on mitochondrial dysfunction. The group also examines the influence of transcription factors like Serum Response Factor (SRF) on mitochondrial processes and the implications of alternative splicing for gene family diversity and protein function. Collaborations within the University of Arkansas for Medical Sciences, including with Jeanne Y. Wei, Pankaj Patyal, Ambika Verma, and Shakshi Sharma, contribute to the breadth of this research, which is supported by Azhar's extensive publication record and high citation count.
Metrics
- h-index: 33
- Publications: 533
- Citations: 3,181
Selected Publications
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Biology of Aging I Antisense Oligonucleotide-Mediated SRF Reduction Ameliorates Mitochondrial Dysfunction in Cardiac Aging (2025)
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Dysregulation of SRF-Regulated Genes Accelerates the Development of Myocardial Aging (2025)
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Assessment of Caregiver Stress Across Dementia and Non-Dementia Groups (2025)
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Isoform-specific roles of SIRT2 in regulating mitochondrial gene expression (2025)
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P. gingivalis-LPS Activates the Alzheimer’s Disease-Associated Amyloid Secretase Pathway via Caspase-4 (2025)
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Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas (2025)
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RETRACTED: Duloxetine, an SNRI, Targets pSTAT3 Signaling: In-Silico, RNA-Seq and In-Vitro Evidence for a Pleiotropic Mechanism of Pain Relief (2025)
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Mitochondrial Dynamics in Aging Heart (2025)
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Assessment of electrolyte abnormalities in older adults with COVID-19 and delirium (2025)
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Alternative Splicing of Serum Response Factor Reveals Isoform-Specific Remodeling in Cardiac Diseases (2025)
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Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases (2025)
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Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer’s Disease Pathologies (2025)
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Cardiac-specific overexpression of serum response factor regulates age-associated decline in mitochondrial function (2025)
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KNOWLEDGE GAPS REGARDING NALOXONE USE AMONG OLDER ADULTS IN HIGH OPIOID PRESCRIBING REGIONS IN SOUTHERN USA (2024)
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DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Arkansas Claude Pepper Older Americans Independence Center at UAMS NIH
- State Targeted Response (STR) No-Cost Extension AR Dept of Human Services/Division of Aging and Adult Services
- Consortium w/Essential: Nutritional Therapy in the Elderly with Heart Failure- Resubmission NIH/Nat. Inst. on Aging via Essential Blends, LLC
- Wolfe-FORTE: Effects of Fortetropin on Skeletal Muscle Protein Fractional Synthetic Rate in Older Men and Women MYOS RENS via University of California, Berkeley
- TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine NIH
- Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, & tolerability of AVP-786 (deudextromethorphan hydrobromide/quinidine sulfate) for agitation treatment in patients w/ dementia of the Alzheimer's type Avanir Pharmaceuticals
- Advancing Health Disparities Research in Aging: The Aging Research in Criminal Justice & Health (ARCH) Network NIH
- Overcoming TWEAK Signaling to Restore Muscle and Mobility Function after Joint Replacement - Continuation - Continuation NIH/National Institutes of Health via University of Alabama at Birmingham
- Ferrando - D.E.B. Dairy - Effect of Dietary Protein Intake Distribution on Protein Metabolism and Skeletal Muscle National Dairy Council
- Ferrando - Dairy Macronutrient Effects on the Metabolic System The Dairy Research Institute
- Arkansas DHS State Opioid Response Grant Supplement SAMHSA
- Subcontract w/Essential Blends, LLC: UpBeat Phase 2 NIH/Nat. Inst. on Aging via Essential Blends, LLC
- PRagmatic EValuation of evENTS And Benefits of Lipid-lowering in oldEr adults (PREVENTABLE) (IRB 274254) NIH/Nat. Inst. on Aging via Duke University
- Transcription Regulation in the Aging Heart NIH
- DAABHS SOR III OPAL Narcan Drug Project Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services
- State Opioid Response Grant Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services
- Care Coordination and Home Telehealth Program for Older Adults with Cardiovascular Disease NIH/Nat. Inst. on Aging via Environment and Health Group, Inc.
Collaboration Network
Top Collaborators
Jeanne Y. Wei
University of Arkansas for Medical Sciences
44 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning
- Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
Showing 5 of 44 shared publications
Xiaomin Zhang
Institute on Aging (US)
21 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
Showing 5 of 21 shared publications
Pankaj Patyal
University of Arkansas for Medical Sciences
21 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 21 shared publications
Ambika Verma
University of Arkansas for Medical Sciences
20 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 20 shared publications
Shakshi Sharma
Institute on Aging
13 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Mitochondrial Dynamics in Aging Heart
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
Showing 5 of 13 shared publications
Amanda Pangle
Institute on Aging
9 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Disparity and Multimorbidity in Heart Failure Patients Over the Age of 80
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
Showing 5 of 9 shared publications
Karen Coker
University of Arkansas for Medical Sciences
6 shared publications
In database
- Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
- A Response to: Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic [Response to Letter]
Showing 5 of 6 shared publications
Robert R. Wolfe
Institute on Aging
6 shared publications
In database
- Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
Showing 5 of 6 shared publications
Fathima S. Ameer
Institute on Aging
5 shared publications
In database
- Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Sirtuin gene isoforms and genomic sequences of mouse and humans: Divergence across species
- SIRTUIN 1 ISOFORMS DIFFERENTIALLY IMPACT MITOCHONDRIAL GENE EXPRESSION AND FUNCTION IN MUSCLE CELLS
Priya Mendiratta
University of Arkansas for Medical Sciences (US)
4 shared publications
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- The PBAR Protocol: Antipsychotic Medication Reduction in the Nursing Home
- HEALTHCARE DISPARITY IN THE ASSESSMENT OF DEMENTIA IN THE PRIMARY CARE SETTING
- A Response to: Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic [Response to Letter]
Wei Zhang
University of Arkansas at Little Rock
4 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Neutrophil Biomarkers Can Predict Cardiotoxicity of Anthracyclines in Breast Cancer
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
- Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases
Yingni Che
University of Arkansas for Medical Sciences
4 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Neutrophil Biomarkers Can Predict Cardiotoxicity of Anthracyclines in Breast Cancer
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
Sayed Aliul Hasan Abdi
University of Arkansas for Medical Sciences
4 shared publications
In database
- Mitochondrial Dynamics in Aging Heart
- The Long-Term Cardiovascular Risks of Duloxetine Use in Older Adults: A Retrospective Medical Record-Based Adverse Drug Reaction Assessment
- Alternative Splicing of Serum Response Factor Reveals Isoform-Specific Remodeling in Cardiac Diseases
- Duloxetine, an SNRI, Targets pSTAT3 Signaling: In-Silico, RNA-Seq and In-Vitro Evidence for a Pleiotropic Mechanism of Pain Relief
Arny A. Ferrando
Institute on Aging
3 shared publications
In database
- Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning
- The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial
- Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial
Grishma KC
Institute on Aging
3 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
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