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Likely match
Presence
Current · Arkansas
Last published
2023
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
M
Meenakshi Upreti
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Also affiliated: University of Kentucky (2012–2017); Jawaharlal Nehru University (2004–2005); University of Arkansas System (2005–2006); Albert B. Chandler Hospital (2016); Markey Cancer Center (2016–2017)
18 h-index
45 pubs
1,041 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Meenakshi Upreti's research focuses on the molecular mechanisms of apoptosis, particularly in response to chemotherapeutic agents. Her work investigates the role of key proteins, such as Bak and Bax, in initiating programmed cell death. Upreti has published research on the activation of Bak and its interaction with Bax in the apoptotic response to vinblastine, a common chemotherapy drug. This research utilizes cell lines and animal models to understand cellular survival and death pathways. Upreti has a publication record of 45 papers, with over 1,000 citations, and an h-index of 18, indicating a consistent output of scholarly work in her field. She has collaborated with researchers Elena Galitovskaya and Timothy C. Chambers at the University of Arkansas for Medical Sciences on multiple publications.
Metrics
- h-index: 18
- Publications: 45
- Citations: 1,041
Selected Publications
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Data from Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine (2023)
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Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells (2012)
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Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth (2012)
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Vascular Disrupting Agent Arsenic Trioxide Enhances Thermoradiotherapy of Solid Tumors (2012)
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Abstract 5288: Tumor-endothelial 3D spheroids for dynamic imaging of cancer progression (2011)
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Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics (2011)
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ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans. (2010)
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Inferring Functional Relationships and Causal Network Structure from Gene Expression Profiles (2010)
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Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling (2010)
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Granger Causality Analysis of Human Cell-Cycle Gene Expression Profiles (2010)
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Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis (2009)
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Cyclin-Dependent Kinase 1-Mediated Bcl-x L /Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis (2009)
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Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans (2009)
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Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine (2008)
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Identifying Non-random Patterns from Gene Expression Profiles (2008)
Collaboration Network
Top Collaborators
Timothy C. Chambers
University of Arkansas for Medical Sciences
9 shared publications
In database
- Cyclin-Dependent Kinase 1-Mediated Bcl-x L /Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis
- Identification of the Major Phosphorylation Site in Bcl-xL Induced by Microtubule Inhibitors and Analysis of Its Functional Significance
- Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
- Vinblastine-induced Apoptosis Is Mediated by Discrete Alterations in Subcellular Location, Oligomeric Structure, and Activation Status of Specific Bcl-2 Family Members
- Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis
Showing 5 of 9 shared publications
Radhakrishnan Nagarajan
University of Arkansas for Medical Sciences (US)
7 shared publications
- Granger Causality Analysis of Human Cell-Cycle Gene Expression Profiles
- Comment on causality and pathway search in microarray time series experiment
- Qualitative assessment of cDNA microarray gene expression data using detrended fluctuation analysis
- Qualitative assessment of gene expression in affymetrix genechip arrays
- Inferring Functional Relationships and Causal Network Structure from Gene Expression Profiles
Showing 5 of 7 shared publications
Elena Galitovskaya
University of Arkansas for Medical Sciences
5 shared publications
In database
- Identification of the Major Phosphorylation Site in Bcl-xL Induced by Microtubule Inhibitors and Analysis of Its Functional Significance
- Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
- Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans
- ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans.
- Data from Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
Robert J. Griffin
University of Arkansas for Medical Sciences
5 shared publications
In database
- Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
- Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling
- Vascular Disrupting Agent Arsenic Trioxide Enhances Thermoradiotherapy of Solid Tumors
- Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth
- Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells
Nathan A. Koonce
University of Arkansas for Medical Sciences
5 shared publications
In database
- Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
- Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling
- Vascular Disrupting Agent Arsenic Trioxide Enhances Thermoradiotherapy of Solid Tumors
- Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth
- Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells
Azemat Jamshidi‐Parsian
University of Arkansas for Medical Sciences
3 shared publications
In database
- Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
- Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth
- Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells
Rong Chu
University of Arkansas for Medical Sciences (US)
3 shared publications
- Identification of the Major Phosphorylation Site in Bcl-xL Induced by Microtubule Inhibitors and Analysis of Its Functional Significance
- Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
- Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis
T. David Bateman
University of Arkansas at Fayetteville (US)
2 shared publications
- Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans
- ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans.
Aarti Joshi
University of Arkansas at Fayetteville (US)
2 shared publications
- Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans
- ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans.
Kwangyul Moon
University of Arkansas at Fayetteville (US)
2 shared publications
- Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans
- ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans.
Matthias C. McIntosh
University of Arkansas at Fayetteville (US)
2 shared publications
- Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans
- ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans.
David Terrano
University of Arkansas for Medical Sciences (US)
2 shared publications
- Cyclin-Dependent Kinase 1-Mediated Bcl-x L /Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis
- Identification of the Major Phosphorylation Site in Bcl-xL Induced by Microtubule Inhibitors and Analysis of Its Functional Significance
Leah Hennings
University of Arkansas for Medical Sciences (US)
2 shared publications
- Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling
- Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth
Jessica Webber
University of Arkansas for Medical Sciences
2 shared publications
In database
- Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
- Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells
Sherri K. Smart
University of Arkansas for Medical Sciences (US)
2 shared publications
- Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
- Data from Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine
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