Gene Expression And Cancer Classification
85 researchers across 9 institutions
Scientists investigate how genes are activated and deactivated to understand the development and progression of cancer. This research involves analyzing gene expression patterns in various cancer types to identify molecular signatures that can distinguish between different subtypes. Methodologies include advanced genomic sequencing, bioinformatics, and the development of computational models to interpret complex biological data. Studies also explore how alterations in gene expression contribute to cancer cell growth, survival, and the ability of cancer to spread (metastasis).
This work is relevant to Arkansas's public health landscape by seeking to improve cancer diagnosis and treatment strategies. Understanding specific gene expression profiles can lead to more precise classification of cancers, enabling personalized medicine approaches tailored to individual patient needs. This research also has potential implications for the state's bioscience industry, fostering innovation in diagnostic tools and therapeutic development.
This area of study draws upon expertise in molecular biology, genomics, and computational science. Collaboration among researchers at multiple Arkansas institutions strengthens the collective capacity to address complex questions in cancer biology and classification.
Top Researchers
| Name | Institution | h-index | Citations | Career Stage | Badges |
|---|---|---|---|---|---|
| John D. Shaughnessy | UAMS | 89 | 31,735 | Faculty | High Impact |
| Frits van Rhee | UAMS | 83 | 27,050 | Faculty | High Impact |
| Fenghuang Zhan | UAMS | 68 | 19,565 | Faculty | Grant PI High Impact |
| Andy Pereira | University of Arkansas | 52 | 12,819 | Faculty | High Impact |
| Dan A. Dixon | UAMS | 46 | 8,586 | Faculty | High Impact |
| Volodymyr Tryndyak | NCTR | 44 | 7,008 | High Impact | |
| Erming Tian | UAMS | 32 | 5,650 | High Impact | |
| Mary Qu Yang | UA Little Rock | 31 | 5,288 | Faculty | ARA High Impact |
| Christian K. Tipsmark | University of Arkansas | 30 | 2,396 | High Impact | |
| Kyounghyun Kim | UAMS | 29 | 5,555 | Faculty | High Impact |
| Rosalia C. M. Simmen | UAMS | 29 | 2,514 | High Impact | |
| Michael P. Popp | University of Arkansas | 24 | 1,729 | Faculty | High Impact Grants |
| Lawrence E. Cornett | UAMS | 24 | 1,626 | Faculty | Grant PI High Impact |
| Horacio Gómez-Acevedo | UAMS | 18 | 1,369 | Faculty | |
| Bailu Peng | UAMS | 18 | 2,512 | ||
| Mohammad Alinoor Rahman | UAMS | 17 | 1,247 | Faculty | Grant PI |
| Samantha L. Kendrick | UAMS | 17 | 1,902 | Faculty | Grant PI |
| Sayem Miah | UAMS | 15 | 539 | Faculty | |
| Sara K Orlowski | University of Arkansas | 15 | 830 | ||
| Andrea M. Moerman-Herzog | UAMS | 14 | 605 | Postdoctoral |
Related Research Areas
Strategic Outlook
Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW
Top US institutions in this area
- 1 Harvard University 2,080
- 2 Stanford University 1,470
- 3 National Institutes of Health 1,181
- 4 University of Michigan 1,149
- 5 Johns Hopkins University 1,107
Cross-Institution Connections
Researchers at different institutions with overlapping expertise in Gene Expression And Cancer Classification.