Wayne G. Shreffler
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Division Chief
Also affiliated: Broad Institute (2019–2025); Northwestern University (2010); University of North Carolina at Chapel Hill (2022–2023); Universidade Federal do Rio de Janeiro (1994); Center for Infectious Disease Research (1992–1993); National Institutes of Health (2024); Mount Sinai Health System (2004); Mount Sinai Hospital (2004–2010); Children's Hospital of Philadelphia (2021); Harvard University (2011–2026); Johns Hopkins University (2024); Duke University (2004); Hebrew University of Jerusalem (2021–2026); Johns Hopkins Medicine (2024); NYU Langone Health (1993–1997); Massachusetts General Hospital (2010–2026); Children's Hospital Colorado (2021); National Institute of Allergy and Infectious Diseases (2024); Johns Hopkins Hospital (2024); Arkansas Children's Research Institute (2026); New York University (1993–1997); Massachusetts Institute of Technology (2019–2025); Charité - Universitätsmedizin Berlin (2004); Icahn School of Medicine at Mount Sinai (2004–2024)
Biomedical Subjects
Links
Biography and Research Information
Metrics
- h-index: 60
- Publications: 361
- Citations: 13,408
Positions
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Division Chief 2009–presentMassachusetts General Hospital Pediatric Allergy / Immunology ORCID
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Division Chief publications 2026University of Arkansas for Medical Sciences ORCID
Selected Publications
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Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis (2026)
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Management of Gastrointestinal Symptoms During Oral Immunotherapy: Guidance from OUtMATCH Investigators (2026)
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Exploratory analyses of predictors and correlates of response to omalizumab therapy in patients with multiple food allergies (2025)
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Multiomics approach to evaluating personalized biomarkers of allergen immunotherapy (2025)
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Germline-encoded recognition of peanut underlies development of convergent antibodies in humans (2025)
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Introduction of allergenic foods after treatment with omalizumab (2025)
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Biomarker-driven drug development for allergic diseases and asthma: An FDA public workshop (2025)
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Dietary plant diversity predicts early life microbiome maturation (2025)
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Long-Term Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: An Open-Label Active Treatment (REALISE Study) (2025)
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Moving Beyond Desensitization to Tolerance in Food Allergy (2025)
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Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis (2025)
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First-in-human VLP Peanut Vaccine Candidate: Safety and Tolerability Data from on-going Phase I/IIa Clinical Trial (2025)
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Treatment of Multi-Food Allergy with Omalizumab Compared to Omalizumab-Facilitated Multi-Allergen OIT (2025)
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A molecular basis for milk allergen immune recognition in eosinophilic esophagitis (2025)
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Interferon-γ Signaling in Eosinophilic Esophagitis Affects Epithelial Barrier Function and Programmed Cell Death (2025)
Collaboration Network
Top Collaborators
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- Tolerance to extensively heated milk in children with cow's milk allergy
- Immunologic changes in children with egg allergy ingesting extensively heated egg
- Oral peanut immunotherapy in children with peanut anaphylaxis
- Microarray immunoassay: Association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes
Showing 5 of 41 shared publications
- Prospective Assessment of Pediatrician-Diagnosed Food Protein–Induced Allergic Proctocolitis by Gross or Occult Blood
- Early decrease in basophil sensitivity to Ara h 2 precedes sustained unresponsiveness after peanut oral immunotherapy
- Food aversion and poor weight gain in food protein–induced enterocolitis syndrome: A retrospective study
- Expansion of the CD4+ effector T-cell repertoire characterizes peanut-allergic patients with heightened clinical sensitivity
- Increased IgE-Mediated Food Allergy With Food Protein-Induced Allergic Proctocolitis
Showing 5 of 28 shared publications
- The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease
- Sialylation of immunoglobulin E is a determinant of allergic pathogenicity
- Peanut oral immunotherapy transiently expands circulating Ara h 2–specific B cells with a homologous repertoire in unrelated subjects
- Early decrease in basophil sensitivity to Ara h 2 precedes sustained unresponsiveness after peanut oral immunotherapy
- Human BCR analysis of single-sorted, putative IgE+ memory B cells in food allergy
Showing 5 of 26 shared publications
- Clinical efficacy and immune regulation with peanut oral immunotherapy
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- Omalizumab for the Treatment of Multiple Food Allergies
- Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy
- Evidence of pathway‐specific basophil anergy induced by peanut oral immunotherapy in peanut‐allergic children
Showing 5 of 25 shared publications
- Clonally expanded, GPR15-expressing pathogenic effector T H 2 cells are associated with eosinophilic esophagitis
- Prospective Assessment of Pediatrician-Diagnosed Food Protein–Induced Allergic Proctocolitis by Gross or Occult Blood
- Cesarean section and antibiotic use found to be associated with eosinophilic esophagitis
- Tolerance of baked milk in patients with cow's milk–mediated eosinophilic esophagitis
- Food aversion and poor weight gain in food protein–induced enterocolitis syndrome: A retrospective study
Showing 5 of 23 shared publications
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- Tolerance to extensively heated milk in children with cow's milk allergy
- Immunologic changes in children with egg allergy ingesting extensively heated egg
- Omalizumab for the Treatment of Multiple Food Allergies
- Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy
Showing 5 of 21 shared publications
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- Omalizumab for the Treatment of Multiple Food Allergies
- Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy
- The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population
- Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy
Showing 5 of 20 shared publications
- Clinical efficacy and immune regulation with peanut oral immunotherapy
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- Sublingual immunotherapy for peanut allergy: Clinical and immunologic evidence of desensitization
- Omalizumab for the Treatment of Multiple Food Allergies
- Evidence of pathway‐specific basophil anergy induced by peanut oral immunotherapy in peanut‐allergic children
Showing 5 of 20 shared publications
- Omalizumab for the Treatment of Multiple Food Allergies
- Prospective Assessment of Pediatrician-Diagnosed Food Protein–Induced Allergic Proctocolitis by Gross or Occult Blood
- Cesarean section and antibiotic use found to be associated with eosinophilic esophagitis
- Age and eczema severity, but not family history, are major risk factors for peanut allergy in infancy
- Ara h 2–specific IgE is superior to whole peanut extract–based serology or skin prick test for diagnosis of peanut allergy in infancy
Showing 5 of 19 shared publications
- TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures
- Peanut oral immunotherapy transiently expands circulating Ara h 2–specific B cells with a homologous repertoire in unrelated subjects
- Clonally expanded, GPR15-expressing pathogenic effector T H 2 cells are associated with eosinophilic esophagitis
- Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells
- The role of dendritic cells in food allergy
Showing 5 of 17 shared publications
- Sublingual immunotherapy for peanut allergy: Clinical and immunologic evidence of desensitization
- Omalizumab for the Treatment of Multiple Food Allergies
- Long-term, open-label extension study of the efficacy and safety of epicutaneous immunotherapy for peanut allergy in children: PEOPLE 3-year results
- Updating the CoFAR Grading Scale for Systemic Allergic Reactions in Food Allergy
- Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results
Showing 5 of 17 shared publications
- Clinical efficacy and immune regulation with peanut oral immunotherapy
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- Sublingual immunotherapy for peanut allergy: Clinical and immunologic evidence of desensitization
- Microarray immunoassay: Association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes
- The Major Glycoprotein Allergen from Arachis hypogaea, Ara h 1, Is a Ligand of Dendritic Cell-Specific ICAM-Grabbing Nonintegrin and Acts as a Th2 Adjuvant In Vitro
Showing 5 of 16 shared publications
- Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy
- Long-term, open-label extension study of the efficacy and safety of epicutaneous immunotherapy for peanut allergy in children: PEOPLE 3-year results
- Updating the CoFAR Grading Scale for Systemic Allergic Reactions in Food Allergy
- Consensus report from the Food Allergy Research & Education (FARE) 2019 Oral Immunotherapy for Food Allergy Summit
- Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results
Showing 5 of 14 shared publications
- Prospective Assessment of Pediatrician-Diagnosed Food Protein–Induced Allergic Proctocolitis by Gross or Occult Blood
- Food aversion and poor weight gain in food protein–induced enterocolitis syndrome: A retrospective study
- Increased IgE-Mediated Food Allergy With Food Protein-Induced Allergic Proctocolitis
- Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis
- Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens
Showing 5 of 14 shared publications
- Tolerance to extensively heated milk in children with cow's milk allergy
- Immunologic changes in children with egg allergy ingesting extensively heated egg
- Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy
- Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein
- Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergy
Showing 5 of 13 shared publications