Marcelo Bigarella Institution Verified

OverviewAI-generated summary

Marcelo Bigarella's research focuses on the diagnosis and understanding of prostate cancer, particularly utilizing advanced imaging and molecular techniques. He has investigated the role of prostate zonal impact and 5α-reductase inhibitors on multiparametric MRI characteristics for cancer detection. His work also explores the utility of PSMA PET/MRI in improving the accuracy of detecting clinically significant prostate cancer in men on active surveillance, as evidenced by results from Phase II diagnostic trials. Bigarella has also contributed to understanding circulating tumor cells, specifically developing multiplex assays to assess activated p300/CBP and identifying alterations in SIRT2-H3K18Ac in patients with castration-resistant prostate cancer. His research interests extend to the stem cell origin of cancer and strategies for chemoprevention and maintenance therapy.

Metrics

• h-index: 2
• Publications: 18
• Citations: 12