Jiali Li
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
Also affiliated: Rutgers, The State University of New Jersey (2009–2010); Harvard University (2002–2004); Ulsan National Institute of Science and Technology (2017); Yangzhou University (2021)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jiali Li's research focuses on the application of nanotechnology, particularly solid-state nanopore sensors, for characterizing biomolecules. Her work investigates the size and shape of protein oligomers in solution, including alpha-synuclein and beta-lactoglobulin, contributing to the understanding of protein aggregation mechanisms relevant to various diseases. Li also studies the aggregation and conformational changes of tau and tubulin proteins using nanopore methods in conjunction with atomic force microscopy. Her lab has developed and functionally characterized immortalized rabbit dermal papilla cell lines. Further research explores the amplification mechanisms of bent DNA sensors through all-atom molecular dynamics simulations and the sensing of RNA stability using silicon nitride nanopore devices.
Metrics
- h-index: 23
- Publications: 57
- Citations: 5,232
Positions
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Professor 2016–presentUniversity of Arkansas Department of Physics ORCID
Selected Publications
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Tracking single-molecule ferritin reassembly and disassembly using polymer-coated nanopores (2025)
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Understanding the Mechanism of Bent DNA Amplifying Sensors Using All-Atom Molecular Dynamics Simulations (2025)
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BPS2025 - Sensing RNA stability by a silicon nitride nanopore device (2025)
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Dependence of protein shape and stability on electric field strength and solution environment (2024)
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Probing heat shock protein-coding RNA of Sulfolobus solfataricus P2 through a solid-state nanopore under different pH and temperature (2024)
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Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor (2023)
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Detecting DNA-Binding Sites of Regulation Proteins with Ion Beam Sculpted Silicon Nitride Nanopores (2023)
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Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution (2023)
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Aggregation and Oligomerization Characterization of ß-lactoglobulin Protein by a Solid State Nanopore Sensor (2023)
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Tau and tubulin protein aggregation characterization by solid-state nanopore method and atomic force microscopy (2023)
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Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution (2023)
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Fluid surface coatings for solid-state nanopores: comparison of phospholipid bilayers and archaea-inspired lipid monolayers (2019)
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Estimation of Shape, Volume, and Dipole Moment of Individual Proteins Freely Transiting a Synthetic Nanopore (2019)
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Estimating RNA Polymerase Protein Binding Sites on λ DNA Using Solid-State Nanopores (2018)
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A tip-attached tuning fork sensor for the control of DNA translocation through a nanopore (2017)
Collaboration Network
Top Collaborators
- Controlling protein translocation through nanopores with bio-inspired fluid walls
- Real-time shape approximation and fingerprinting of single proteins using a nanopore
- Single-Particle Characterization of Aβ Oligomers in Solution
- Characterization of Protein Unfolding with Solid-state Nanopores
- Probing Access Resistance of Solid‐State Nanopores with a Scanning‐Probe Microscope Tip
Showing 5 of 13 shared publications
- Controlling protein translocation through nanopores with bio-inspired fluid walls
- Estimation of Shape, Volume, and Dipole Moment of Individual Proteins Freely Transiting a Synthetic Nanopore
- Single-Particle Characterization of Aβ Oligomers in Solution
- Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution
- Fluid surface coatings for solid-state nanopores: comparison of phospholipid bilayers and archaea-inspired lipid monolayers
Showing 5 of 9 shared publications
- Slowing DNA Translocation in a Solid-State Nanopore
- Detecting Single Stranded DNA with a Solid State Nanopore
- Electrical characterization of protein molecules by a solid-state nanopore
- K + , N a + , and M g 2+ on DNA translocation in silicon nitride nanopores
- Estimating RNA Polymerase Protein Binding Sites on λ DNA Using Solid-State Nanopores
Showing 5 of 8 shared publications
- Detecting Single Stranded DNA with a Solid State Nanopore
- Electrical characterization of protein molecules by a solid-state nanopore
- Nanopore sculpting with noble gas ions
- Characterization of Protein Unfolding with Solid-state Nanopores
- Sensing Single Protein Molecules with Solid-State Nanopores
Showing 5 of 7 shared publications
- Slowing DNA Translocation in a Solid-State Nanopore
- Detecting Single Stranded DNA with a Solid State Nanopore
- Electrical characterization of protein molecules by a solid-state nanopore
- DNA conformation and base number simultaneously determined in a nanopore
- Characterization of Protein Unfolding with Solid-state Nanopores
Showing 5 of 7 shared publications
- Real-time shape approximation and fingerprinting of single proteins using a nanopore
- Estimation of Shape, Volume, and Dipole Moment of Individual Proteins Freely Transiting a Synthetic Nanopore
- Estimating RNA Polymerase Protein Binding Sites on λ DNA Using Solid-State Nanopores
- The effects of geometry and stability of solid-state nanopores on detecting single DNA molecules
- Nanoparticle Shape and Size Characterization with Solid State Nanopores
Showing 5 of 7 shared publications
- Directly Observing the Motion of DNA Molecules near Solid-State Nanopores
- Probing Access Resistance of Solid‐State Nanopores with a Scanning‐Probe Microscope Tip
- Threading Immobilized DNA Molecules through a Solid-State Nanopore at >100 μs per Base Rate
- DNA motion induced by electrokinetic flow near an Au coated nanopore surface as voltage controlled gate
- A tip-attached tuning fork sensor for the control of DNA translocation through a nanopore
Showing 5 of 7 shared publications
- Single-Molecule Protein Unfolding in Solid State Nanopores
- The distribution of DNA translocation times in solid-state nanopores
- Sensing Single Protein Molecules with Solid-State Nanopores
- Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor
- Corrigendum: The distribution of DNA translocation times in solid-state nanopores
Showing 5 of 6 shared publications
- Threading Immobilized DNA Molecules through a Solid-State Nanopore at >100 μs per Base Rate
- Estimating RNA Polymerase Protein Binding Sites on λ DNA Using Solid-State Nanopores
- A tip-attached tuning fork sensor for the control of DNA translocation through a nanopore
- Threading Immobilized DNA Molecules Through Solid-State Nanopores
- Sensing the Binding Sites of RNAP Holoenzyme on λ DNA Attached to a Probe Tip with Solid State Nanopores
Showing 5 of 6 shared publications
- Controlling protein translocation through nanopores with bio-inspired fluid walls
- Real-time shape approximation and fingerprinting of single proteins using a nanopore
- Single-Particle Characterization of Aβ Oligomers in Solution
- Lipid Bilayers in Nanopores to Vary their Diameter, Characterize Amyloid-β Aggregates and Monitor the Activity of Membrane-Active Enzymes
- Nanopores with Fluid Walls for Determining the Shape, Dipole Moment, and Rotational Diffusion Coefficient of Non-Spherical Proteins
Showing 5 of 6 shared publications
- Detecting Single Stranded DNA with a Solid State Nanopore
- Nanopore sculpting with noble gas ions
- Feedback-controlled ion beam sculpting apparatus
- Nanopore fabrication in amorphous Si: Viscous flow model and comparison to experiment
- Solid-State Nanopore for Detecting Individual Biopolymers
- Estimation of Shape, Volume, and Dipole Moment of Individual Proteins Freely Transiting a Synthetic Nanopore
- Estimating RNA Polymerase Protein Binding Sites on λ DNA Using Solid-State Nanopores
- Tau and tubulin protein aggregation characterization by solid-state nanopore method and atomic force microscopy
- Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor
- Aggregation and Oligomerization Characterization of ß-lactoglobulin Protein by a Solid State Nanopore Sensor
- Estimation of Shape, Volume, and Dipole Moment of Individual Proteins Freely Transiting a Synthetic Nanopore
- Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution
- Fluid surface coatings for solid-state nanopores: comparison of phospholipid bilayers and archaea-inspired lipid monolayers
- Tracking single-molecule ferritin reassembly and disassembly using polymer-coated nanopores
- Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution
- Slowing DNA Translocation in a Solid-State Nanopore
- K + , N a + , and M g 2+ on DNA translocation in silicon nitride nanopores
- Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor
- Aggregation and Oligomerization Characterization of ß-lactoglobulin Protein by a Solid State Nanopore Sensor
- Real-time shape approximation and fingerprinting of single proteins using a nanopore
- Single-Particle Characterization of Aβ Oligomers in Solution
- Nanopores with Fluid Walls for Determining the Shape, Dipole Moment, and Rotational Diffusion Coefficient of Non-Spherical Proteins
- Characterizing Shape, Dipole Moment, and Rotation of Single Proteins in Nanopores
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