Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-06
J
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
John E. George's research has focused on the mechanisms of disease and potential therapeutic interventions, particularly in the context of pancreatitis and cancer. He has investigated the role of pirfenidone, a drug known for its anti-fibrotic properties, in ameliorating both acute and chronic pancreatitis in murine models. His work in this area has explored the drug's impact on immune responses and cytokine modulation, specifically highlighting the requirement of IL-10 for pirfenidone's beneficial effects in chronic pancreatitis models. Additionally, George has examined the influence of heat shock protein 70 (Hsp70) on immune responses in pancreatic cancer, with a particular focus on its interaction with dendritic cells.
Metrics
- h-index: 38
- Publications: 200
- Citations: 4,678
Selected Publications
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Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis Prophylaxis: Does the Choice of Crystalloid Fluid Matter? A Systematic Review and Meta-analysis of Randomized Controlled Trials (2025)
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S2729 Magnetically Guided Capsule Endoscopy for Detecting Esophageal Varices: Systematic Review and Meta-Analysis (2025)
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Efficacy and safety of pregabalin in managing pain of chronic pancreatitis: A systematic review and meta-analysis of randomized controlled trials (2025)
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S963 Pooled Diagnostic Accuracy of Methylated DNA Biomarker Panels from Nonendoscopic Cell Collection Devices for Barrett’s Esophagus and Neoplasia Detection (2025)
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Impact of pancreatic steatosis on risk of Post-ERCP pancreatitis: Systematic review and meta-analysis (2025)
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Atrial Fibrillation Burden Predicts Increased HeartLogic Index and Risk of Heart Failure Decompensation in Patients With Cardiac Implantable Electronic Devices (2025)
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Innovative Technologies for Non-Intrusive Aflatoxin Detection in Pistachios (2025)
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Advancing post ERCP pancreatitis prevention—insights from pharmacokinetics of rectal NSAIDs (2025)
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Postoperative Nausea and Vomiting Management for Adults in the Ambulatory Surgical Setting (2024)
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ASO Visual Abstract: The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review From the Society for Ambulatory Anesthesia (SAMBA) (2022)
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Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation (2022)
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The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review from the Society for Ambulatory Anesthesia (SAMBA) (2022)
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ASO Author Reflections: SAMBA’s Practice Advisory for the Use of Pectoralis Blocks in Breast Surgery: Overview and Lingering Questions (2022)
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Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models (2021)
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Recent Status of Covid-19 Pandemic: A Perspective to Global and Indian Scenario (2021)
Collaboration Network
Top Collaborators
Rajinder Dawra
Sylvester Comprehensive Cancer Center (US)
6 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
- Su303 IL10 IS REQUIRED FOR THE BENEFICIAL EFFECT OF PIRFENIDONE IN MOUSE MODELS OF WELL-ESTABLISHED CHRONIC PANCREATITIS
- Su299 THERAPEUTIC INHIBITION OF ADAM 10&17 AMELIORATES SEVERITY OF ACUTE PANCREATITIS
Showing 5 of 6 shared publications
Ejas Palathingal Bava
University of Alabama at Birmingham (US)
5 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
- Su303 IL10 IS REQUIRED FOR THE BENEFICIAL EFFECT OF PIRFENIDONE IN MOUSE MODELS OF WELL-ESTABLISHED CHRONIC PANCREATITIS
- Su299 THERAPEUTIC INHIBITION OF ADAM 10&17 AMELIORATES SEVERITY OF ACUTE PANCREATITIS
Vikas Dudeja
University of Alabama at Birmingham (US)
5 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
- Su303 IL10 IS REQUIRED FOR THE BENEFICIAL EFFECT OF PIRFENIDONE IN MOUSE MODELS OF WELL-ESTABLISHED CHRONIC PANCREATITIS
- Su299 THERAPEUTIC INHIBITION OF ADAM 10&17 AMELIORATES SEVERITY OF ACUTE PANCREATITIS
Tareq Alsaleh
AdventHealth Orlando (US)
5 shared publications
- Impact of pancreatic steatosis on risk of Post-ERCP pancreatitis: Systematic review and meta-analysis
- S963 Pooled Diagnostic Accuracy of Methylated DNA Biomarker Panels from Nonendoscopic Cell Collection Devices for Barrett’s Esophagus and Neoplasia Detection
- Efficacy and safety of pregabalin in managing pain of chronic pancreatitis: A systematic review and meta-analysis of randomized controlled trials
- S2729 Magnetically Guided Capsule Endoscopy for Detecting Esophageal Varices: Systematic Review and Meta-Analysis
- Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis Prophylaxis: Does the Choice of Crystalloid Fluid Matter? A Systematic Review and Meta-analysis of Randomized Controlled Trials
Srikanth Iyer
University of Alabama at Birmingham (US)
4 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
- Su303 IL10 IS REQUIRED FOR THE BENEFICIAL EFFECT OF PIRFENIDONE IN MOUSE MODELS OF WELL-ESTABLISHED CHRONIC PANCREATITIS
Ashok K. Saluja
University of Miami (US)
4 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
- Su303 IL10 IS REQUIRED FOR THE BENEFICIAL EFFECT OF PIRFENIDONE IN MOUSE MODELS OF WELL-ESTABLISHED CHRONIC PANCREATITIS
Bhuwan Giri
University of Miami (US)
3 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Prateek Sharma
University of Alabama at Birmingham (US)
3 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Tejeshwar Jain
University of Alabama at Birmingham (US)
3 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Utpreksha Vaish
University of Alabama at Birmingham (US)
3 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Preeti Sahay
University of Alabama at Birmingham (US)
3 shared publications
- Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
- Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation
- Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Alberto E. Ardon
Mayo Clinic in Florida (US)
3 shared publications
- The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review from the Society for Ambulatory Anesthesia (SAMBA)
- ASO Author Reflections: SAMBA’s Practice Advisory for the Use of Pectoralis Blocks in Breast Surgery: Overview and Lingering Questions
- ASO Visual Abstract: The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review From the Society for Ambulatory Anesthesia (SAMBA)
Michael O’Rourke
Edward Hines, Jr. VA Hospital (US)
3 shared publications
- The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review from the Society for Ambulatory Anesthesia (SAMBA)
- ASO Author Reflections: SAMBA’s Practice Advisory for the Use of Pectoralis Blocks in Breast Surgery: Overview and Lingering Questions
- ASO Visual Abstract: The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review From the Society for Ambulatory Anesthesia (SAMBA)
Melinda Seering
University of Iowa (US)
3 shared publications
- The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review from the Society for Ambulatory Anesthesia (SAMBA)
- ASO Author Reflections: SAMBA’s Practice Advisory for the Use of Pectoralis Blocks in Breast Surgery: Overview and Lingering Questions
- ASO Visual Abstract: The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review From the Society for Ambulatory Anesthesia (SAMBA)
Hanae K. Tokita
Memorial Sloan Kettering Cancer Center (US)
3 shared publications
- The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review from the Society for Ambulatory Anesthesia (SAMBA)
- ASO Author Reflections: SAMBA’s Practice Advisory for the Use of Pectoralis Blocks in Breast Surgery: Overview and Lingering Questions
- ASO Visual Abstract: The Use of Pectoralis Blocks in Breast Surgery: A Practice Advisory and Narrative Review From the Society for Ambulatory Anesthesia (SAMBA)
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