Zhiqiang Qin
Associate Professor
Also affiliated: Qingdao University (2017–2018); Zhejiang Sci-Tech University (2023); National Institute for Parasitic Diseases (2014); Medical University of South Carolina (2010–2011); Chinese Center For Disease Control and Prevention (2014); MUSC Hollings Cancer Center (2010); Nanjing Maternity and Child Health Care Hospital (2020); Ministry of Education (2012); The People's Hospital of Guangxi Zhuang Autonomous Region (2021–2025); Qingdao Municipal Hospital (2018); Jiangsu Cancer Hospital (2016); Institute of Forensic Science (2021–2023); Jiangsu Province Hospital (2016–2021); Nanjing Jiangning Hospital (2019); Nanjing First Hospital (2018–2023); Zhejiang University (2013); Henan Medical University (2013); Nanjing Medical University (2012–2023)
Pathology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Zhiqiang Qin's research focuses on understanding disease mechanisms and developing targeted therapies. He is currently serving as PI on an NIH/National Institute of Dental and Craniofacial Research grant for $647,465, investigating the transactivation of human endogenous retrovirus (HERV)-K by oncogenic viruses in HIV+ patients and exploring targeted therapeutic strategies. This work aligns with his broader interests in viral infections and their impact on human health.
With 171 publications and 3,809 citations, Qin has established a significant body of work. His research has explored the role of microRNAs in viral pathogenesis, such as Kaposi’s sarcoma-associated herpesvirus (KSHV)-encoded microRNAs inducing cytokine secretion and facilitating viral dissemination. He has also investigated bacterial biofilm formation and interactions, as well as the potential of microRNAs as tumor suppressors in conditions like renal cell carcinoma. His publication record includes meta-analyses, such as one comparing transrectal and transperineal prostate biopsy techniques.
Qin leads a research group at the University of Arkansas for Medical Sciences, where he is an Associate Professor in Pathology. His scholarly contributions have led to his designation as a high-impact researcher. He has a notable h-index of 35, reflecting the consistent output and influence of his research.
Metrics
- h-index: 35
- Publications: 171
- Citations: 3,809
Positions
-
Associate Professor publications 2019–2025University of Arkansas for Medical Sciences Pathology, College of Medicine Institutional directory
Selected Publications
-
Engineering SIM-1 and MZ-1 PROTACs for enhanced target degradation in KSHV-infected immortalized endothelial cells (2026)
-
Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation (2026)
-
KSHV and Human Diseases: Beyond KS, PEL and MCD (2026)
-
Roles of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway in Oncovirus Infection and Virus-Associated Cancers (2025)
-
Recent Advances in Development of Kaposi's Sarcoma‐Associated Herpesvirus‐Latency‐Associated Nuclear Antigen Targeted Therapies (2025)
-
Abstract 2987: Role of EIF4G1 network in non-small cell lung cancers (NSCLC) pathogenesis and development of targeted therapy (2025)
-
Infection of human induced pluripotent stem cells by an oncogenic herpesvirus (2025)
-
Identification of RP‐54745, an IL‐1 Inhibitor Displaying Anticancer Activities for KSHV‐Related Primary Effusion Lymphoma (2025)
-
Alterations in Cellular Gene Expression Due to Co‐Infection With Kaposi's Sarcoma‐Associated Herpesvirus and SARS‐CoV‐2: Implications for Disease Severity (2024)
-
Roles of Human Endogenous Retrovirus-K-Encoded Np9 in Human Diseases: A Small Protein with Big Functions (2024)
-
Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response (2024)
-
Development of human endogenous retrovirus type K‐ related treatments for human diseases (2024)
-
Role of lymphatic endothelium specific hyaluronan receptor 1 in virus infection and associated diseases (2024)
-
P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension (2024)
-
Coinfections with additional oncoviruses in HPV+ individuals: Status, function and potential clinical implications (2024)
Federal Grants 1 $647,465 total
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Seeds of Science Pilot award UAMS Internal Research Awards Principal Investigator
- Development of O'PROTACs-based Novel EIF4G1 Degraders for Treatment of Non-small Cell Lung Cancer US Department of Defense Principal Investigator
- Defining mechanisms of KSHV pathogenesis using MHV68-KSHV chimeric viruses NIH Co-Investigator
- Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's Sarcoma development in HIV + patients - Continuation NIH/Nat. Cancer Institute Principal Investigator
Collaboration Network
Top Collaborators
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
- SARS‐CoV‐2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?
- Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation
- Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG)
- Kaposi Sarcoma–Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation
Showing 5 of 32 shared publications
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
- Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation
- SARS‐CoV‐2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?
- Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation
- Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG)
Showing 5 of 20 shared publications
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
- Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation
- SARS‐CoV‐2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?
- Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation
- Kaposi Sarcoma–Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation
Showing 5 of 18 shared publications
- Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG)
- Ubiquitin Modification of the Epstein-Barr Virus Immediate Early Transactivator Zta
- Role of EIF4G1 network in non‐small cell lung cancers (NSCLC) cell survival and disease progression
- Identification of natural compounds tubercidin and lycorine HCl against small‐cell lung cancer and BCAT1 as a therapeutic target
- Oncolytic strategy using new bifunctional HDACs/BRD4 inhibitors against virus-associated lymphomas
Showing 5 of 9 shared publications
- Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response
- Roles of Human Endogenous Retrovirus-K-Encoded Np9 in Human Diseases: A Small Protein with Big Functions
- Development of human endogenous retrovirus type K‐ related treatments for human diseases
- Roles of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway in Oncovirus Infection and Virus-Associated Cancers
- Alterations in Cellular Gene Expression Due to Co‐Infection With Kaposi's Sarcoma‐Associated Herpesvirus and SARS‐CoV‐2: Implications for Disease Severity
Showing 5 of 9 shared publications
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
- Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation
- Porphyromonas gingivalis coinfects with KSHV in oral cavities of HIV+ patients and induces viral lytic reactivation
- Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis
- Echinomycin as a promising therapeutic agent against KSHV-related malignancies
Showing 5 of 8 shared publications
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
- Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG)
- Kaposi's sarcoma‐associated herpesvirus and extracellular vesicles
- Identification of natural compounds tubercidin and lycorine HCl against small‐cell lung cancer and BCAT1 as a therapeutic target
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
Showing 5 of 8 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- Identification of natural compounds tubercidin and lycorine HCl against small‐cell lung cancer and BCAT1 as a therapeutic target
- Echinomycin as a promising therapeutic agent against KSHV-related malignancies
- Targeting Sphingosine Kinase by ABC294640 against Diffuse Intrinsic Pontine Glioma (DIPG)
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
Showing 5 of 8 shared publications
- Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation
- Role of EIF4G1 network in non‐small cell lung cancers (NSCLC) cell survival and disease progression
- Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis
- Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma
- Abstract 4384: Role of EIF4G1 in non-small cell lung cancer pathogenesis and targeted therapy
- The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways
- Identification of natural compounds tubercidin and lycorine HCl against small‐cell lung cancer and BCAT1 as a therapeutic target
- Oncolytic strategy using new bifunctional HDACs/BRD4 inhibitors against virus-associated lymphomas
- Mechanistic Insights into Chemoresistance Mediated by Oncogenic Viruses in Lymphomas
- SARS‐CoV‐2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?
- Echinomycin as a promising therapeutic agent against KSHV-related malignancies
- Activation of IL1 signaling molecules by Kaposi’s sarcoma-associated herpesvirus
- Role of Histamine and Related Signaling in Kaposi’s Sarcoma-Associated Herpesvirus Pathogenesis and Oncogenesis
- Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation
- Kaposi Sarcoma–Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation
- Role of EIF4G1 network in non‐small cell lung cancers (NSCLC) cell survival and disease progression
- Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation
- Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation
- Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients
- SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
- Echinomycin as a promising therapeutic agent against KSHV-related malignancies
- Activation of IL1 signaling molecules by Kaposi’s sarcoma-associated herpesvirus
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Identification of RP‐54745, an IL‐1 Inhibitor Displaying Anticancer Activities for KSHV‐Related Primary Effusion Lymphoma
Similar Researchers
Based on overlapping research topics