Abigail L Zirbel
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Researcher
Also affiliated: Clemson University (2024)
Graduate Student Researcher
Research Areas
Biography and Research Information
OverviewAI-generated summary
Abigail L Zirbel's research investigates the impact of nutrient deficiencies on cellular energy metabolism, with a particular focus on mitochondrial function in muscle cells. Her work has explored how iron depletion affects the activity of mitochondrial complexes, specifically Complex I, and the protein levels of key components like NDUFB8 and ISCU. Zirbel has also examined the consequences of combined folate deficiency and the loss of the SHMT2 gene on protein expression related to oxidative phosphorylation, folate transport, and mitochondrial dynamics in mouse C2C12 myoblast cells. Her recent publications include studies on energy metabolism under iron-limited conditions and the molecular mechanisms underlying these changes. Zirbel collaborates with Joanna Fiddler and Makenzie A Tharpe at the University of Arkansas at Fayetteville on these research endeavors.
Metrics
- h-index: 1
- Publications: 3
- Citations: 1
Selected Publications
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Transient MYC Mimicking the Exercise Response Orchestrates Multifaceted Skeletal Muscle Adaptations (2026)
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Loss of SHMT2 and Folate Deficiency Impair Protein Levels Involved in Oxidative Phosphorylation, Folate Transport, and Mitochondrial Dynamics in Mouse C2C12 Myoblast Cells (2025)
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Marginal Iron Depletion Impairs Mitochondrial Complex I Activity and Reduces NDUFB8 and ISCU Protein Levels in Mouse C2C12 Myoblast Cells (2025)
Collaboration Network
Top Collaborators
- Marginal Iron Depletion Impairs Mitochondrial Complex I Activity and Reduces NDUFB8 and ISCU Protein Levels in Mouse C2C12 Myoblast Cells
- Loss of SHMT2 and Folate Deficiency Impair Protein Levels Involved in Oxidative Phosphorylation, Folate Transport, and Mitochondrial Dynamics in Mouse C2C12 Myoblast Cells
- Marginal Iron Depletion Impairs Mitochondrial Complex I Activity and Reduces NDUFB8 and ISCU Protein Levels in Mouse C2C12 Myoblast Cells
- Loss of SHMT2 and Folate Deficiency Impair Protein Levels Involved in Oxidative Phosphorylation, Folate Transport, and Mitochondrial Dynamics in Mouse C2C12 Myoblast Cells
- Marginal Iron Depletion Impairs Mitochondrial Complex I Activity and Reduces NDUFB8 and ISCU Protein Levels in Mouse C2C12 Myoblast Cells
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