Chandrabose Karthikeyan
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Associate Staff Scientist
Also affiliated: Rajiv Gandhi Technical University (2007–2020); Health Sciences North (2021); Indira Gandhi National Tribal University (2018–2026); Bentham Science Publishers (United Arab Emirates) (2014); Shri Govindram Seksaria Institute of Technology and Science (2004–2006); University of Benin (2009); Bharati Vidyapeeth (Deemed to be University) (2021)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Chandrabose Karthikeyan's research focuses on the development and application of nanomaterials for targeted drug delivery, particularly in cancer therapy. He investigates the functionalization of materials such as multi-walled carbon nanotubes and graphene quantum dots with specific ligands to enhance their efficacy in delivering chemotherapeutic agents like doxorubicin to cancer cells. His work also addresses the inherent toxicity of carbon nanotubes, exploring methods like curcumin coating to mitigate these effects.
His research extends to exploring novel nanocarriers for drug delivery, including lysinated multiwalled carbon nanotubes conjugated with carbohydrate ligands for targeted delivery to breast cancer cells, and multifunctional graphene quantum dots for receptor targeting, drug delivery, and bioimaging in pancreatic cancer. Karthikeyan also has an interest in applying computational methods, such as quantitative structure-activity relationship (QSAR) modeling, to drug design and prediction. He has explored the use of deep learning for predicting disease stages, as seen in his work on diabetic retinopathy.
Karthikeyan's publication record includes studies on the pharmacological effects of various agents, the molecular mechanisms of diseases, and the synthesis and application of nanomaterials. His work has been cited over 2,400 times, contributing to a body of knowledge in nanomedicine and cancer therapeutics. He has collaborated with researchers at the University of Arkansas for Medical Sciences on several projects.
Metrics
- h-index: 27
- Publications: 137
- Citations: 2,286
Positions
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Associate Staff Scientist 2024–presentUniversity of Arkansas for Medical Sciences College of Pharmacy ORCID
Selected Publications
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Oxcarbazepine (2026)
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Vacuolization as a Novel Approach to Cancer Therapy (2026)
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Abstract LB315: Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer (2026)
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The Therapeutic Promise of Kojic Acid: A Comprehensive Review (2026)
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Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases (2025)
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Patent landscape in hydroxamic acid-based HDAC inhibitors (2020–2024): structure–activity relationships and mechanistic insights (2025)
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The hidden hand of endoplasmic reticulum stress in anticancer drug resistance (2025)
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Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells (2025)
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Thienopyrimidine derivatives TPH104c and TPH104m induce JNK/BNIP3-mediated mitochondrial dysfunction and promotes mitophagy in triple-negative breast cancer (2025)
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Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases (2025)
Collaboration Network
Top Collaborators
- The hidden hand of endoplasmic reticulum stress in anticancer drug resistance
- Thienopyrimidine derivatives TPH104c and TPH104m induce JNK/BNIP3-mediated mitochondrial dysfunction and promotes mitophagy in triple-negative breast cancer
- Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
- Vacuolization as a Novel Approach to Cancer Therapy
- Thienopyrimidine derivatives TPH104c and TPH104m induce JNK/BNIP3-mediated mitochondrial dysfunction and promotes mitophagy in triple-negative breast cancer
- Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
- Patent landscape in hydroxamic acid-based HDAC inhibitors (2020–2024): structure–activity relationships and mechanistic insights
- The hidden hand of endoplasmic reticulum stress in anticancer drug resistance
- Abstract LB315: Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer
- Vacuolization as a Novel Approach to Cancer Therapy
- The hidden hand of endoplasmic reticulum stress in anticancer drug resistance
- Abstract LB315: Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer
- Vacuolization as a Novel Approach to Cancer Therapy
- Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Thienopyrimidine derivatives TPH104c and TPH104m induce JNK/BNIP3-mediated mitochondrial dysfunction and promotes mitophagy in triple-negative breast cancer
- Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
- Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
- Vacuolization as a Novel Approach to Cancer Therapy
- The hidden hand of endoplasmic reticulum stress in anticancer drug resistance
- Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
- Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells
- Vacuolization as a Novel Approach to Cancer Therapy
- The hidden hand of endoplasmic reticulum stress in anticancer drug resistance
- Vacuolization as a Novel Approach to Cancer Therapy
- Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
- Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases
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