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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
C
Chhanda Bose
High Impact
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20 h-index
63 pubs
1,078 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Chhanda Bose's research focuses on understanding disease mechanisms, particularly in the context of aging and cancer. Her work has explored the protective effects of sulforaphane, a compound found in cruciferous vegetables, against age-associated cardiac and muscular dysfunction by investigating its influence on Nrf2 signaling. Bose has also examined the potential of sulforaphane to enhance the anticancer efficacy of doxorubicin while mitigating its cardiotoxic side effects in a breast cancer model.
Further investigations by Bose delve into the molecular underpinnings of neurological disorders, specifically Alzheimer's disease, by studying the role of synaptosome microRNAs in regulating synaptic functions. Her earlier work includes contributions to molecular biology techniques, such as improvements to solid phase phosphotriester synthesis of deoxyoligonucleotides and the development of a derivatization reagent for HPLC-MS analysis of biological organic acids. Bose has also published on the chemopreventive properties of diallyl disulfide, a component of garlic, and its role in inducing glutathione transferase in mouse tissues.
Bose's research network includes collaborations with Sharda P. Singh, Philip Palade, Oleg Karaduta, and Sudhir V. Shah, all affiliated with the University of Arkansas for Medical Sciences. Her scholarly output is reflected in an h-index of 20 and over 1,000 citations across 63 publications, designating her as a highly cited researcher.
Metrics
- h-index: 20
- Publications: 63
- Citations: 1,078
Selected Publications
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Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging (2025)
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Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site (2019)
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P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN (2018)
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Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model (2018)
Collaboration Network
Top Collaborators
Sudhir V. Shah
Central Arkansas Veterans Healthcare System
6 shared publications
In database
- Impact of Hydroxychloroquine on Atherosclerosis and Vascular Stiffness in the Presence of Chronic Kidney Disease
- Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury
- Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
- Recent Advances in Understanding the Pathogenesis of Atherosclerosis in CKD Patients
- Gadolinium Contrast Agent-Induced CD163+ Ferroportin+ Osteogenic Cells in Nephrogenic Systemic Fibrosis
Showing 5 of 6 shared publications
Kodetthoor B. Udupa
Central Arkansas Veterans Healthcare System (US)
5 shared publications
- Activation of p-ERK1/2 by nicotine in pancreatic tumor cell line AR42J: effects on proliferation and secretion
- Nicotine‐induced proliferation of isolated rat pancreatic acinar cells: effect on cell signalling and function
- Age-related alteration in hepatic acyl-CoA: cholesterol acyltransferase and its relation to LDL receptor and MAPK
- Altered Mitogen-Activated Protein Kinase Signal Transduction in Human Skin Fibroblasts During In Vitro Aging: Differential Expression of Low-Density Lipoprotein Receptor
- Identification of Erythroid Cell Stimulating Factor as a Unique Protein, Quiescin Q6: Role in Erythropoiesis.
Oleg K. Karaduta
Central Arkansas Veterans Healthcare System
4 shared publications
In database
- Impact of Hydroxychloroquine on Atherosclerosis and Vascular Stiffness in the Presence of Chronic Kidney Disease
- Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury
- Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
Sundararaman Swaminathan
Central Arkansas Veterans Healthcare System (US)
3 shared publications
- Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
- Gadolinium Contrast Agent-Induced CD163+ Ferroportin+ Osteogenic Cells in Nephrogenic Systemic Fibrosis
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
Sharda Prakash Singh
Central Arkansas Veterans Healthcare System
3 shared publications
In database
- Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model
- A New Derivatization Reagent for HPLC–MS Analysis of Biological Organic Acids
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
Judit K. Megyesi
University of Arkansas for Medical Sciences
2 shared publications
In database
- Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
Kim M. Hiatt
University of Arkansas for Medical Sciences (US)
2 shared publications
- Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
- Gadolinium Contrast Agent-Induced CD163+ Ferroportin+ Osteogenic Cells in Nephrogenic Systemic Fibrosis
Kimberly A. Hall
University of Arkansas for Medical Sciences (US)
2 shared publications
- Evidence Suggesting a Role of Iron in a Mouse Model of Nephrogenic Systemic Fibrosis
- Gadolinium Contrast Agent-Induced CD163+ Ferroportin+ Osteogenic Cells in Nephrogenic Systemic Fibrosis
Chidambaram Bhuvaneswaran
2 shared publications
- Age-related alteration in hepatic acyl-CoA: cholesterol acyltransferase and its relation to LDL receptor and MAPK
- Altered Mitogen-Activated Protein Kinase Signal Transduction in Human Skin Fibroblasts During In Vitro Aging: Differential Expression of Low-Density Lipoprotein Receptor
Ashutosh M. Shukla
University of Florida (US)
2 shared publications
- Impact of Hydroxychloroquine on Atherosclerosis and Vascular Stiffness in the Presence of Chronic Kidney Disease
- Recent Advances in Understanding the Pathogenesis of Atherosclerosis in CKD Patients
Gur P. Kaushal
Central Arkansas Veterans Healthcare System (US)
2 shared publications
- Impact of Hydroxychloroquine on Atherosclerosis and Vascular Stiffness in the Presence of Chronic Kidney Disease
- Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury
Paul A. Parcon
University of Arkansas for Medical Sciences (US)
2 shared publications
- Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
- P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN
Meenakshisundaram Balasubramaniam
University of Arkansas for Medical Sciences
2 shared publications
In database
- Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
- P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN
Richard A. Jones
Central Arkansas Veterans Healthcare System (US)
2 shared publications
- Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
- P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN
Martin Rhys Farlow
Indiana University Bloomington (US)
2 shared publications
- Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
- P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN
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