Biography and Research Information
OverviewAI-generated summary
Chhanda Bose's research investigates molecular mechanisms underlying neurodegenerative diseases, particularly Alzheimer's disease. Her work has explored the role of synaptosome microRNAs in regulating synaptic functions and the protective effects of small molecule inhibitors, such as DDQ, against amyloid beta and tau-induced toxicities. Bose has also studied the involvement of RALBP1 in oxidative stress and mitochondrial dysfunction within the context of Alzheimer's disease, and the potential of Rlip76 as a factor in neurodegeneration. Beyond neurodegeneration, her research has touched upon the anticancer activity of omega-6 fatty acids and the impact of iron chelation on age-related skeletal muscle sarcopenia in aging models.
Bose's scholarly contributions are reflected in her h-index of 20, with over 1,000 citations across 63 publications. She has established collaborations with several researchers at the University of Arkansas for Medical Sciences, including Sharda P. Singh, with whom she shares 19 publications, and Philip Palade, with whom she has 5 shared publications. Her recent activity indicates continued engagement in research, with a publication in 2025.
Metrics
- h-index: 20
- Publications: 63
- Citations: 1,078
Selected Publications
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Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging (2025)
Collaboration Network
Top Collaborators
Sharda P. Singh
Texas Tech University
18 shared publications
In database
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
- The role of RLIP76 in oxidative stress and mitochondrial dysfunction: Evidence based on autopsy brains from Alzheimer's disease patients
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
Showing 5 of 18 shared publications
P. Hemachandra Reddy
Texas Tech University (US)
15 shared publications
- Synaptosome microRNAs regulate synapse functions in Alzheimer’s disease
- Protective effects of a small molecule inhibitor, DDQ against amyloid beta in Alzheimer’s disease
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Anti-brain Aging Effects of Small Molecule Inhibitor DDQ
- Protective effects of a small-molecule inhibitor DDQ against tau-induced toxicities in a transgenic tau mouse model of Alzheimer’s disease
Showing 5 of 15 shared publications
Ashly Hindle
Texas Tech University Health Sciences Center (US)
15 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
- The role of RLIP76 in oxidative stress and mitochondrial dysfunction: Evidence based on autopsy brains from Alzheimer's disease patients
- Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights
Showing 5 of 15 shared publications
Sanjay Awasthi
8 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
- Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Rlip Protein: A Potential Target for COVID-19
Showing 5 of 8 shared publications
Sudhir Kshirsagar
Texas Tech University (US)
8 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
- The role of RLIP76 in oxidative stress and mitochondrial dysfunction: Evidence based on autopsy brains from Alzheimer's disease patients
- Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights
- Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights
Showing 5 of 8 shared publications
Murali Vijayan
Texas Tech University (US)
7 shared publications
- Protective effects of a small molecule inhibitor, DDQ against amyloid beta in Alzheimer’s disease
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Anti-brain Aging Effects of Small Molecule Inhibitor DDQ
- Protective effects of a small-molecule inhibitor DDQ against tau-induced toxicities in a transgenic tau mouse model of Alzheimer’s disease
- Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
Showing 5 of 7 shared publications
Philip Palade
University of Arkansas for Medical Sciences
5 shared publications
In database
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
- Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels
Jangampalli Adi Pradeepkiran
Texas Tech University (US)
5 shared publications
- Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
- Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights
- Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights
- Corrigendum to “Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights” [Biochim. Biophys. Acta Mol. Basis Dis. 2023 Oct;1869(7):166759. doi: 10.1016/j.bbadis.2023.166759. Epub 2023 May 22. PMID: 37225106]
- Correction: Reddy et al. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells 2023, 12, 1646
Jonathan Kopel
4 shared publications
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
- Rlip Protein: A Potential Target for COVID-19
- List of contributors
Arubala P. Reddy
Texas Tech University (US)
4 shared publications
- Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights
- Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights
- Corrigendum to “Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights” [Biochim. Biophys. Acta Mol. Basis Dis. 2023 Oct;1869(7):166759. doi: 10.1016/j.bbadis.2023.166759. Epub 2023 May 22. PMID: 37225106]
- Correction: Reddy et al. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells 2023, 12, 1646
Ji‐Hyun Lee
Texas Tech University (US)
3 shared publications
- Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
- Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels
Rakhshanda Layeequr Rahman
MetroHealth Medical Center (US)
3 shared publications
- Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis
- Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer
- Combination of immune checkpoint inhibition with cryoablation augments T cell activation in the tumor immune microenvironment (TIME) - it is about TIME! 2575
Mathew George
Texas Tech University (US)
3 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Protective effects of a small-molecule inhibitor DDQ against tau-induced toxicities in a transgenic tau mouse model of Alzheimer’s disease
- Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
Lloyd E. Bunquin
Texas Tech University (US)
3 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Protective effects of a small-molecule inhibitor DDQ against tau-induced toxicities in a transgenic tau mouse model of Alzheimer’s disease
- Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
Neha Sawant
Texas Tech University (US)
3 shared publications
- RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
- Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
- Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
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