Biography and Research Information
OverviewAI-generated summary
Chhanda Bose investigates the molecular mechanisms underlying Alzheimer's disease, focusing on the roles of oxidative stress, mitochondrial dysfunction, and specific signaling pathways. Her recent publications explore the protective effects of small molecule inhibitors, such as DDQ, against amyloid beta and tau pathologies in Alzheimer's disease models. Bose's work also examines the function of the RALBP1 (RLIP76) protein in relation to oxidative stress and mitochondrial dysfunction in the context of Alzheimer's disease, with studies investigating its role in autopsy brains from affected patients.
Her research utilizes animal models, including transgenic tau mice, and human brain tissue to understand disease progression and identify potential therapeutic targets. Bose has also published on the impact of synaptosome microRNAs on synapse functions in Alzheimer's disease. Her scholarship metrics include an h-index of 20, with over 1,000 citations across 63 publications, and she is recognized as a highly cited researcher. Key collaborators include Sharda P. Singh, Philip Palade, Oleg Karaduta, and Sudhir V. Shah, all affiliated with the University of Arkansas for Medical Sciences.
Metrics
- h-index: 20
- Publications: 63
- Citations: 1,078
Selected Publications
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Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging (2025)
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Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site (2019)
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P2‐181: IL‐1β INFLUENCES AUTOPHAGY BY MEDIATING UPREGULATION OF PARKIN AND PARKIN NEDDYLATION IN CELL CULTURE AND ANIMAL MODELS, AND MIMICS THE PATTERN SEEN IN AD BRAIN (2018)
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Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model (2018)
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A New Derivatization Reagent for HPLC–MS Analysis of Biological Organic Acids (2017)
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Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury (2016)
Collaboration Network
Top Collaborators
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
- Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging
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