Chia Y. Lee

Federal Grant PI High Impact

Professor

University of Arkansas for Medical Sciences

faculty

Microbiology & Immunology, College of Medicine

36 h-index 60 pubs 4,597 cited

Research Areas

Links

ORCID Lab Website Research Group UAMS TRI Profile

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OverviewAI-generated summary

Chia Y. Lee, Professor in the Department of Microbiology & Immunology at the University of Arkansas for Medical Sciences, investigates bacterial pathogenesis, with a focus on *Staphylococcus aureus*. Her research group studies the surface polysaccharides and regulatory mechanisms of this bacterium. Current federal funding includes two grants from the NIH/National Institute of Allergy and Infectious Diseases, totaling $457,500, for projects investigating a novel *S. aureus* biofilm polysaccharide and the modulation of the Agr system by the ClpC chaperone.

Dr. Lee's work has resulted in 60 publications with over 4,500 citations, and she holds an h-index of 36. Her recent publications explore the characterization of a specific *N*-acetylgalactosamine-containing surface polysaccharide in *S. aureus*, the regulation of the staphylococcal capsule by SarZ, and the development of a rat model for orthopedic implant-associated infections to identify staphylococcal biofilm proteins. She collaborates with researchers within the University of Arkansas for Medical Sciences, including Matthew A. Jorgenson.

Metrics

h-index: 36
Publications: 60
Citations: 4,597

Selected Publications

Characterization of Ssc, an <i>N</i> -acetylgalactosamine-containing <i>Staphylococcus aureus</i> surface polysaccharide (2024) DOI
Regulation of Staphylococcal Capsule by SarZ is SigA-Dependent (2022) DOI
A Rat Model of Orthopedic Implant-Associated Infection for Identification of Staphylococcal Biofilm Proteins (2021) DOI

Federal Grants 2 $457,500 total

NIH/National Institute of Allergy and Infectious Diseases Contact PI Mar 2023 - Feb 2026

Modulation of Agr system by ClpC chaperone in S. aureus

National Institute of Allergy and Infectious Diseases $229,500 R21

NIH/National Institute of Allergy and Infectious Diseases Contact PI Mar 2021 - Feb 2024

Characterization of a novel S. aureus biofilm polysaccharide

National Institute of Allergy and Infectious Diseases $228,000 R21

Grants & Funding

Regulation of biofilm formation in clinical isolates of Staphylococcus aureus NIH Co-Investigator
Proteomic analysis of S aureus biofilm in vivo NIH Principal Investigator
Regulation of biofilm formation in clinical isolates of Staphylococcus aureus NIH Co-Investigator
STAPHYLOCOCCAL CAPSULE AND VIRULENCE NIH Principal Investigator
Global regulation by mgr in S. aureus NIH Principal Investigator
Virulence gene regulation in Staphylococcus aureus NIH Select
Virulence gene regulation in Staphylococcus aureus NIH Principal Investigator
Capsule regulatory network in S. aureus pathogenesis NIH Principal Investigator