Mei G. Lei
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Research Associate Professor
Also affiliated: University of Toronto (1981); The University of Kansas Cancer Center (1993); University of Kansas Medical Center (1988–2000); Saint Luke's Hospital (2001); University of Missouri–Kansas City (2001–2005)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Mei G. Lei's research has focused on the molecular mechanisms of bacterial infections and host-pathogen interactions, particularly involving *Staphylococcus aureus*. Her work has investigated the genetic regulation of bacterial adhesion and biofilm formation, with publications exploring how specific genes and regulatory proteins influence these processes. Lei has also examined the interaction of bacteria with mammalian cells, including the identification of endotoxin receptors and the binding characteristics of lipopolysaccharides on immune cells.
Her research has explored strategies to attenuate bacterial virulence, including the role of metabolic pathways in *S. aureus* pathogenesis. Beyond bacterial studies, Lei's recent work has touched upon the therapeutic potential of natural compounds, such as algal polysaccharides for atherosclerosis, and the enhancement of antigen-specific tolerance using nanoparticle delivery systems. Her scholarship metrics include an h-index of 25, with 61 total publications and 1,911 total citations. She has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Chia Y. Lee, Ravi Kr. Gupta, Matthew A. Jorgenson, and Emily J. Robbs.
Metrics
- h-index: 23
- Publications: 39
- Citations: 1,602
Positions
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Research Associate Professor publications 2008–2024University of Arkansas for Medical Sciences Institution web page
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Teaching Assistant 2017–2018University of Texas at Austin Biomedical Engineering ORCID
Selected Publications
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Characterization of Ssc, an N -acetylgalactosamine-containing Staphylococcus aureus surface polysaccharide (2024)
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Regulation of Staphylococcal Capsule by SarZ is SigA-Dependent (2022)
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A Rat Model of Orthopedic Implant-Associated Infection for Identification of Staphylococcal Biofilm Proteins (2021)
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MgrA Activates Staphylococcal Capsule via SigA-Dependent Promoter (2020)
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MgrA Negatively Impacts Staphylococcus aureus Invasion by Regulating Capsule and FnbA (2019)
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Contribution of hla Regulation by SaeR to Staphylococcus aureus USA300 Pathogenesis (2019)
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Repression of Capsule Production by XdrA and CodY in Staphylococcus aureus (2018)
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Proteomics of Staphylococcus aureus biofilm matrix in a rat model of orthopedic implant-associated infection (2017)
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SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman (2015)
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RbsR Activates Capsule but Represses the rbsUDK Operon in Staphylococcus aureus (2015)
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Trapping and Identification of Cellular Substrates of the Staphylococcus aureus ClpC Chaperone (2014)
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Activation of sarX by Rbf Is Required for Biofilm Formation and icaADBC Expression in Staphylococcus aureus (2013)
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Trapping and Identification of Cellular Substrates of the Staphylococcus aureus ClpC Chaperone (2013)
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Genetic regulation of the intercellular adhesion locus in staphylococci (2012)
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A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome (2012)
Collaboration Network
Top Collaborators
- Genetic regulation of the intercellular adhesion locus in staphylococci
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- Tricarboxylic Acid Cycle-Dependent Attenuation of Staphylococcus aureus In Vivo Virulence by Selective Inhibition of Amino Acid Transport
- SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman
- Rsp Inhibits Attachment and Biofilm Formation by Repressing fnbA in Staphylococcus aureus MW2
Showing 5 of 19 shared publications
- Genetic regulation of the intercellular adhesion locus in staphylococci
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman
- Rsp Inhibits Attachment and Biofilm Formation by Repressing fnbA in Staphylococcus aureus MW2
- Activation of sarX by Rbf Is Required for Biofilm Formation and icaADBC Expression in Staphylococcus aureus
Showing 5 of 6 shared publications
- Trapping and Identification of Cellular Substrates of the Staphylococcus aureus ClpC Chaperone
- A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome
- Trapping and Identification of Cellular Substrates of the Staphylococcus aureus ClpC Chaperone
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- Staphylococcus aureus Rbf Activates Biofilm Formation In Vitro and Promotes Virulence in a Murine Foreign Body Infection Model
- MgrA Negatively Impacts Staphylococcus aureus Invasion by Regulating Capsule and FnbA
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- Rsp Inhibits Attachment and Biofilm Formation by Repressing fnbA in Staphylococcus aureus MW2
- SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman
- A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome
- Contribution of hla Regulation by SaeR to Staphylococcus aureus USA300 Pathogenesis
- MgrA Negatively Impacts Staphylococcus aureus Invasion by Regulating Capsule and FnbA
- Rsp Inhibits Attachment and Biofilm Formation by Repressing fnbA in Staphylococcus aureus MW2
- A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome
- SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman
- SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
- Rbf Promotes Biofilm Formation by Staphylococcus aureus via Repression of icaR , a Negative Regulator of icaADBC
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