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Biography and Research Information
OverviewAI-generated summary
Christy Simecka's research investigates the impact of human milk oligosaccharides (HMOs) on gene expression, immune response, and metabolite production in mice. Her work examines how HMOs, in conjunction with infant microbiota, shape the gut and immune system. Simecka has also studied the effects of laboratory housing conditions on the core temperature and locomotor activity of mice. Additionally, her research has explored the role of class A scavenger receptors in promoting tumor progression and inducing specific macrophage phenotypes in a mouse model of breast cancer. Simecka has authored 13 publications with 128 citations and an h-index of 7. She has collaborated with researchers at the University of Arkansas for Medical Sciences, including Renee Fox, Aline Andres, Brenda M. Gannon, and William E. Fantegrossi.
Metrics
- h-index: 7
- Publications: 13
- Citations: 130
Selected Publications
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Class A Scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer (2026)
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Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice (2024)
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Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice (2024)
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Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response (2022)
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Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice (2021)
Collaboration Network
Top Collaborators
Manoj Gurung
Arkansas Children's Nutrition Center (US)
3 shared publications
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
- Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Lars Bode
University of California, San Diego (US)
3 shared publications
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
- Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Tanya LeRoith
Virginia Tech (US)
3 shared publications
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
- Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Laxmi Yeruva
Arkansas Children's Nutrition Center (US)
3 shared publications
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
- Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Fernanda Rosa
Texas Tech University (US)
2 shared publications
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Patricia Tripp
Arkansas Children's Nutrition Center (US)
2 shared publications
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Renee Fox
Arkansas Children's Nutrition Center
2 shared publications
In database
- Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice
- Infant Microbiota Communities and Human Milk Oligosaccharide Supplementation Independently and Synergistically Shape Metabolite Production and Immune Responses in Healthy Mice
Lauren Russell
1 shared publication
In database
- Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice
William S. Hyatt
1 shared publication
- Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice
Brenda M. Gannon
1 shared publication
In database
- Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice
Mildred M Randolph
University of Arkansas for Medical Sciences (US)
1 shared publication
- Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice
William E. Fantegrossi
1 shared publication
In database
- Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice
Ashok Sharma
Cedars-Sinai Medical Center (US)
1 shared publication
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
David Casero
Cedars-Sinai Medical Center (US)
1 shared publication
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
Katelin S. Matazel
Agricultural Research Service
1 shared publication
In database
- Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response
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