C
Clay D. Jackson-Litteken
Assistant Professor
faculty
6 h-index
16 pubs
123 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Clay D. Jackson-Litteken's research focuses on understanding bacterial virulence factors and host-pathogen interactions, particularly in the context of lung infections. His work has investigated specific bacterial components, such as the Invasin-Like Adhesin InvL and the diadenylate cyclase CdaA, and their roles in establishing infection and responding to host defenses. Jackson-Litteken has developed and utilized chronic murine models to study long-term *Acinetobacter baumannii* pneumonia, enabling the examination of virulence factors, antibiotic treatments, and polymicrobial infections. His publications explore bacterial strategies like intracellular persistence and resistance, and the potential for existing medications, such as diclofenac, to sensitize multi-drug resistant strains to antibiotics like colistin. He has co-authored publications with researchers at the University of Arkansas for Medical Sciences, including Jon S. Blevins and C. Tyler Ratliff.
Metrics
- h-index: 6
- Publications: 16
- Citations: 123
Selected Publications
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Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i> (2026)
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Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i> (2025)
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A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections (2025)
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Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy (2025)
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Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii (2024)
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Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae (2022)
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The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology (2021)
Collaboration Network
Top Collaborators
Mario F. Feldman
Washington University in St. Louis (US)
10 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- The tRNA methyltransferase TrmB is critical for <i>Acinetobacter baumannii</i> stress responses and pulmonary infection
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections
- A chronic murine model of pulmonary <i>Acinetobacter baumannii</i> infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections
Showing 5 of 10 shared publications
Gisela Di Venanzio
Washington University in St. Louis (US)
9 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- The tRNA methyltransferase TrmB is critical for <i>Acinetobacter baumannii</i> stress responses and pulmonary infection
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections
- A chronic murine model of pulmonary <i>Acinetobacter baumannii</i> infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections
Showing 5 of 9 shared publications
Nichollas E. Scott
The University of Melbourne (AU)
9 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- The tRNA methyltransferase TrmB is critical for <i>Acinetobacter baumannii</i> stress responses and pulmonary infection
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- Intracellular <i>Acinetobacter baumannii</i> acts as a transient reservoir in lung infection via a “persist and resist” strategy
- Diclofenac sensitizes multi-drug resistant <i>Acinetobacter baumannii</i> to colistin
Showing 5 of 9 shared publications
Manon Janet-Maitre
Washington University in St. Louis (US)
5 shared publications
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections
- A chronic murine model of pulmonary <i>Acinetobacter baumannii</i> infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections
- Intracellular <i>Acinetobacter baumannii</i> acts as a transient reservoir in lung infection via a “persist and resist” strategy
- Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy
Evan J. Pardue
4 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- InvL, an invasin-like adhesin, is a type II secretion system substrate required for <i>Acinetobacter baumannii</i> uropathogenesis
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
- Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>
Jon S. Blevins
University of Arkansas for Medical Sciences
3 shared publications
In database
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
Jesús S. Distel
Washington University in St. Louis (US)
3 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- The tRNA methyltransferase TrmB is critical for <i>Acinetobacter baumannii</i> stress responses and pulmonary infection
- InvL, an invasin-like adhesin, is a type II secretion system substrate required for <i>Acinetobacter baumannii</i> uropathogenesis
Jenna C. McGuffey
Washington University in St. Louis (US)
3 shared publications
- The tRNA methyltransferase TrmB is critical for <i>Acinetobacter baumannii</i> stress responses and pulmonary infection
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- Diclofenac sensitizes multi-drug resistant <i>Acinetobacter baumannii</i> to colistin
Juan C. Ortiz‐Marquez
Boston College (US)
3 shared publications
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- Diclofenac sensitizes multi-drug resistant <i>Acinetobacter baumannii</i> to colistin
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
C. Tyler Ratliff
University of Arkansas for Medical Sciences
2 shared publications
In database
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
Job E. López
2 shared publications
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
Nguyen-Hung Le
Washington University in St. Louis (US)
2 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- InvL, an invasin-like adhesin, is a type II secretion system substrate required for <i>Acinetobacter baumannii</i> uropathogenesis
Bardya Djahanschiri
Goethe University Frankfurt (DE)
2 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- InvL, an invasin-like adhesin, is a type II secretion system substrate required for <i>Acinetobacter baumannii</i> uropathogenesis
Ingo Ebersberger
Goethe University Frankfurt (DE)
2 shared publications
- InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis
- InvL, an invasin-like adhesin, is a type II secretion system substrate required for <i>Acinetobacter baumannii</i> uropathogenesis
Fabiana Bisaro
University of Missouri–St. Louis (US)
2 shared publications
- Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
- Diclofenac sensitizes multi-drug resistant <i>Acinetobacter baumannii</i> to colistin
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