Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
C
Clay D. Jackson-Litteken
Assistant Professor
Also affiliated: University of Washington (2024); Washington University in St. Louis (2022–2025); University of Missouri–St. Louis (2024)
Faculty Researcher
6 h-index
16 pubs
133 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Clay D. Jackson-Litteken's research focuses on understanding bacterial virulence factors and host-pathogen interactions, particularly in the context of lung infections. His work has investigated specific bacterial components, such as the Invasin-Like Adhesin InvL and the diadenylate cyclase CdaA, and their roles in establishing infection and responding to host defenses. Jackson-Litteken has developed and utilized chronic murine models to study long-term *Acinetobacter baumannii* pneumonia, enabling the examination of virulence factors, antibiotic treatments, and polymicrobial infections. His publications explore bacterial strategies like intracellular persistence and resistance, and the potential for existing medications, such as diclofenac, to sensitize multi-drug resistant strains to antibiotics like colistin. He has co-authored publications with researchers at the University of Arkansas for Medical Sciences, including Jon S. Blevins and C. Tyler Ratliff.
Metrics
- h-index: 6
- Publications: 16
- Citations: 133
Selected Publications
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Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i> (2026)
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Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i> (2025)
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A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections (2025)
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Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii (2024)
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Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae (2022)
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The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology (2021)
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The BB0345 Hypothetical Protein of Borrelia burgdorferi Is Essential for Mammalian Infection (2020)
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Assessing the Contribution of an HtrA Family Serine Protease During Borrelia turicatae Mammalian Infection (2019)
Collaboration Network
Top Collaborators
Jon S. Blevins
University of Arkansas for Medical Sciences
3 shared publications
In database
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
Nichollas E. Scott
The University of Melbourne (AU)
3 shared publications
- Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
- Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>
Mario F. Feldman
Washington University in St. Louis (US)
3 shared publications
- A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections
- Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
C. Tyler Ratliff
University of Arkansas for Medical Sciences
2 shared publications
In database
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
Job E. López
2 shared publications
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
Manon Janet-Maitre
Washington University in St. Louis (US)
2 shared publications
- A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections
- Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy
Gisela Di Venanzio
Washington University in St. Louis (US)
2 shared publications
- A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections
- Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy
Evan J. Pardue
2 shared publications
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
- Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>
Biswanath Jana
2 shared publications
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
- Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>
Wandy L. Beatty
2 shared publications
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
- Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>
Mohammed Kaplan
University of Chicago (US)
2 shared publications
- Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i>
- Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in <i>Bacteroides thetaiotaomicron</i>
Alexander R. Kneubehl
Baylor College of Medicine (US)
1 shared publication
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
Cheta Siletti
University of Wisconsin–Madison (US)
1 shared publication
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
Lindsay Pack
Arkansas Children's Nutrition Center
1 shared publication
In database
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
Renny S. Lan
Arkansas Children's Nutrition Center
1 shared publication
In database
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
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