Dean W. Roberts
Researcher
Also affiliated: University of Copenhagen (1990); Oklahoma State Department of Health (1946–1951); Arkansas Children's Hospital (2008–2016); United States Food and Drug Administration (2000–2009); University of Kentucky (1994); University of California, San Francisco (2009); Russell Sage Foundation (1955); Medical College of Wisconsin (2009); Health Resources and Services Administration (1946); University of California San Diego (2009); PAREXEL International (United States) (2012); Food and Drug Administration (1999); Institute of Pharmacology (2009); La Salle University (1956); University of Baltimore (1955); The University of Texas Southwestern Medical Center (2009)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Dean W. Roberts' research focuses on the study of acetaminophen toxicity, specifically investigating the development of clinical assays for the determination of acetaminophen protein adducts. His work has also explored the history of acetaminophen toxicity studies.
Roberts is a highly cited researcher with a scholarly output including 116 publications and over 4,300 citations, contributing to a h-index of 34. His recent publications include work on the COVID-19 outbreak at Mission Medium federal penitentiary, alongside his research on acetaminophen. He has collaborated with other researchers at the University of Arkansas for Medical Sciences, including Mitchell R. McGill and Laura P. James, with whom he shares publications.
Metrics
- h-index: 34
- Publications: 116
- Citations: 4,374
Selected Publications
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Development of clinical assays for determination of acetaminophen protein adducts (2024)
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History of acetaminophen toxicity studies (2024)
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Advances in biomarker development in acetaminophen toxicity (2020)
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Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways (2018)
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An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure (2016)
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Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures (2015)
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High Dose Acetaminophen Fails to Promote Airway Hyper-Reactivity Ex Vivo and Is Both Bronchoprotective and Bronchodilatory (2015)
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Isoniazid hepatotoxicity: Progress in understanding the immunologic component (2013)
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Mouse Liver Protein Sulfhydryl Depletion after Acetaminophen Exposure (2012)
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Acetaminophen protein adduct formation following low-dose acetaminophen exposure: comparison of immediate-release vs extended-release formulations (2012)
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A Novel Defensive Mechanism against Acetaminophen Toxicity in the Mouse Lateral Nasal Gland: Role of CYP2A5-Mediated Regulation of Testosterone Homeostasis and Salivary Androgen-Binding Protein Expression (2011)
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The proper use of acetaminophen (2011)
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Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure (2009)
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Quantitative Determination of Skin Penetration of PEG-Coated CdSe Quantum Dots in Dermabraded but not Intact SKH-1 Hairless Mouse Skin (2009)
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Immunotoxicity of Cephalosporins in Mice (2009)
Collaboration Network
Top Collaborators
- History of acetaminophen toxicity studies
- Development of clinical assays for determination of acetaminophen protein adducts
- History of acetaminophen toxicity studies
- Development of clinical assays for determination of acetaminophen protein adducts
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