Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-16
D
Dylan Girodat
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Assistant Professor
Faculty Researcher
9 h-index
33 pubs
590 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Dylan Girodat's research focuses on understanding the molecular mechanisms of protein synthesis, particularly the role of ribosomes and transfer RNA (tRNA) in this process. His work utilizes molecular dynamics simulations to investigate the conformational changes of ribosomes during translation elongation and translocation. Girodat has published research examining the geometric alignment of aminoacyl-tRNA relative to ribosomal catalytic centers, which underpins accurate messenger RNA decoding. He has also investigated the role of specific tRNA movements, such as hyper-swivel head domain motions, in ribosome resetting and translocation. His investigations extend to human protein synthesis, exploring the necessity of tRNA pivoting during proofreading and studying the impact of mutations in ribosomal proteins, such as uL18, on structural dynamics. Girodat collaborates with researchers at the University of Arkansas at Fayetteville, including Anuradha Chowdhury and Divya Sapkota, with whom he has co-authored multiple publications. His scholarship metrics include an h-index of 9, with 33 total publications and 590 total citations.
Metrics
- h-index: 9
- Publications: 33
- Citations: 590
Selected Publications
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Human protein synthesis requires aminoacyl-tRNA pivoting during proofreading (2025)
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Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs (2025)
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Human Protein Synthesis Requires aminoacyl-tRNA Pivoting During Proofreading (2025)
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BPS2025 - Human aminoacyl-tRNA pivots during accommodation (2025)
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BPS2025 - Diamond-Blackfan anemia-associated mutations perturb uL5 helix stability and conformational ensemble (2025)
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BPS2025 - Measurement of nucleotide triphosphate hydrolysis rates and inorganic phosphate release using a coumarin-labeled phosphate binding protein (2025)
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Alternate conformational trajectories in ribosome translocation (2024)
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Implementing Cryo-EM Manual Plunger Techniques in University Workshops and Teaching Laboratories (2024)
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Alternate conformational trajectories in protein synthesis (2024)
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Conformational changes of ribosomes during translation elongation resolved by molecular dynamics simulations (2024)
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Divergent pathways of ribosomal motions during protein synthesis (2024)
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Development of a non-radioactive based assay to measure GTP and ATP hydrolysis rates (2024)
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Impact of Diamond-Blackfan anemia associated mutations on structural dynamics of ribosomal protein uL5 (2024)
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Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding (2023)
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Ribosome hyper-swivel head domain motions are required for translocation and resetting (2023)
Collaboration Network
Top Collaborators
Karissa Y. Sanbonmatsu
Los Alamos National Laboratory (US)
7 shared publications
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding
- Human protein synthesis requires aminoacyl-tRNA pivoting during proofreading
- Ribosome hyper-swivel head domain motions are required for translocation and resetting
- Divergent pathways of ribosomal motions during protein synthesis
Showing 5 of 7 shared publications
Scott C. Blanchard
St. Jude Children's Research Hospital (US)
4 shared publications
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding
- Ribosome hyper-swivel head domain motions are required for translocation and resetting
- Divergent pathways of ribosomal motions during protein synthesis
Hans‐Joachim Wieden
University of Manitoba (CA)
3 shared publications
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding
- Divergent pathways of ribosomal motions during protein synthesis
Anuradha Chowdhury
University of Arkansas at Fayetteville
3 shared publications
In database
- Conformational changes of ribosomes during translation elongation resolved by molecular dynamics simulations
- Impact of Diamond-Blackfan anemia associated mutations on structural dynamics of ribosomal protein uL5
- BPS2025 - Diamond-Blackfan anemia-associated mutations perturb uL5 helix stability and conformational ensemble
Divya Sapkota
University of Arkansas at Fayetteville
3 shared publications
In database
- Conformational changes of ribosomes during translation elongation resolved by molecular dynamics simulations
- Human protein synthesis requires aminoacyl-tRNA pivoting during proofreading
- Human Protein Synthesis Requires aminoacyl-tRNA Pivoting During Proofreading
Divya Sapkota
University of Arkansas at Fayetteville
2 shared publications
In database
- Impact of Diamond-Blackfan anemia associated mutations on structural dynamics of ribosomal protein uL5
- BPS2025 - Diamond-Blackfan anemia-associated mutations perturb uL5 helix stability and conformational ensemble
Samuel Biya-Sambian
University of Arkansas at Fayetteville
2 shared publications
In database
- Development of a non-radioactive based assay to measure GTP and ATP hydrolysis rates
- BPS2025 - Measurement of nucleotide triphosphate hydrolysis rates and inorganic phosphate release using a coumarin-labeled phosphate binding protein
José Luís Pérez Alejo
University of Minnesota (US)
2 shared publications
- Alternate conformational trajectories in ribosome translocation
- Alternate conformational trajectories in protein synthesis
Michael J. Hammerling
Northwestern University (US)
2 shared publications
- Alternate conformational trajectories in ribosome translocation
- Alternate conformational trajectories in protein synthesis
Jessica Willi
Northwestern University (US)
2 shared publications
- Alternate conformational trajectories in ribosome translocation
- Alternate conformational trajectories in protein synthesis
Michael C. Jewett
Northwestern University (US)
2 shared publications
- Alternate conformational trajectories in ribosome translocation
- Alternate conformational trajectories in protein synthesis
Aaron E. Engelhart
University of Minnesota (US)
2 shared publications
- Alternate conformational trajectories in ribosome translocation
- Alternate conformational trajectories in protein synthesis
Katarzyna P. Adamala
University of Minnesota (US)
2 shared publications
- Alternate conformational trajectories in ribosome translocation
- Alternate conformational trajectories in protein synthesis
Wataru Nishima
New Mexico Consortium (US)
1 shared publication
- Ribosome hyper-swivel head domain motions are required for translocation and resetting
Mikael Holm
St. Jude Children's Research Hospital (US)
1 shared publication
- Ribosome hyper-swivel head domain motions are required for translocation and resetting
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