Huidan Zhang Data-verified
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Researcher
faculty
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Biography and Research Information
OverviewAI-generated summary
Huidan Zhang's research investigates mechanisms of disease and potential therapeutic interventions, with a focus on sepsis and its associated complications. Her work has explored the role of the gut microbiota in sepsis-induced encephalopathy in mice, identifying indole-3-propionic acid as a potential therapeutic agent for sepsis-related gut disturbances. Zhang has also examined molecular pathways involved in acute kidney injury, specifically the role of a protein encoded by circular ZNF609 RNA in activating the AKT/mTOR-autophagy pathway.
Beyond disease mechanisms, Zhang's research extends to the development and application of microfluidic technologies, particularly droplet microfluidics, for various scientific applications. She has also contributed to research on materials science, including the synthesis and characterization of cesium lead bromide perovskite quantum dots for their stability and efficiency. Additionally, her work has involved metabolic engineering strategies to obtain high-purity docosahexaenoic acid oil from the microorganism *Aurantiochytrium* and the biosynthesis of triacylglycerol through rational modulation of enzymes in oleaginous microorganisms.
Metrics
- h-index: 31
- Publications: 119
- Citations: 3,288
Selected Publications
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Advances in the transcriptional regulation and lipid droplet turnover in microalgae (2025)
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Acryloyl Gelatin as Polymer Additive to Droplet Digital LAMP for DNA Quantification (2025)
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Combined end-tidal CO2 and diastolic blood pressure–guided CPR improves survival from cardiac arrest in porcine model (2025)
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Subcutaneous delivery of icariin via a gelatin methacryloyl (GelMA) hydrogel sustained-release system improves ovarian function in reproductively aged mice (2025)
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Hierarchically Self‐Assembled Anion‐Coordination‐Driven Gels for Guest Segregation and Electrical Sensing (2025)
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Hierarchically Self‐Assembled Anion‐Coordination‐Driven Gels for Guest Segregation and Electrical Sensing (2025)
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Blood–brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis (2025)
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High color rendering index white laser light source based on RGBY four primary colors (2025)
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High-efficiency perovskite light-emitting diodes enabled by introducing a LiF modification layer (2025)
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Ss-31 Mitigates Post-Cardiac Arrest Brain Injury Via Sesn2-Mediated Inhibition of Microglial Ferroptosis and Modulation of Polarization (2024)
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Preparation and chromatographic properties of ordered macroporous polymer monoliths by colloidal crystal templating method (2024)
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Analysis of Tensile Tests on High-Performance Fiber Fabrics (2024)
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Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System (2024)
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Oocyte Cholesterol Initiates Paternal Genome Decondensation During Fertilization (2024)
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Mevalonate metabolites boost aged oocyte quality through small GTPases prenylation (2024)
Collaboration Network
Top Collaborators
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
- Anti-inflammatory effects and molecular mechanisms of bioactive small molecule garlic polysaccharide
Showing 5 of 10 shared publications
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- Research advances on arachidonic acid production by fermentation and genetic modification of Mortierella alpina
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
Showing 5 of 9 shared publications
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- Research advances on arachidonic acid production by fermentation and genetic modification of Mortierella alpina
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
Showing 5 of 9 shared publications
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
Showing 5 of 7 shared publications
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
- A high-throughput platform enables in situ screening of fatty acid-producing strains using laser ablation electrospray ionization mass spectrometry and a Python package
Showing 5 of 6 shared publications
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
- Use of ultra high performance liquid chromatography with high resolution mass spectrometry to analyze urinary metabolome alterations following acute kidney injury in post-cardiac surgery patients
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
Showing 5 of 6 shared publications
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
- Variations of urinary N-acetyl-β-D-glucosaminidase levels and its performance in detecting acute kidney injury under different thyroid hormones levels: a prospectively recruited, observational study
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
- Variations of urinary N-acetyl-β-D-glucosaminidase levels and its performance in detecting acute kidney injury under different thyroid hormones levels: a prospectively recruited, observational study
- Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma
- Cathelicidin LL-37 promotes EMT, migration and metastasis of hepatocellular carcinoma cells in vitro and mouse model
- Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer
- Intestinal Ecology Changes in Diarrheic Père David’s Deer Revealed by Gut Microbiota and Fecal Metabolites Analysis
- LL-37 Limits the Therapeutic Efficacy of 1,25(OH) 2 D 3 and Suramin for HCC by Enhancing M2 Macrophage Polarization
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- Modular Metabolic Engineering of <i><i>Mortierella alpina</i></i> by the 2A Peptide Platform to Improve Arachidonic Acid Production
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
- Variations of urinary N-acetyl-β-D-glucosaminidase levels and its performance in detecting acute kidney injury under different thyroid hormones levels: a prospectively recruited, observational study
- Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma
- Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer
- Intestinal Ecology Changes in Diarrheic Père David’s Deer Revealed by Gut Microbiota and Fecal Metabolites Analysis
- LL-37 Limits the Therapeutic Efficacy of 1,25(OH) 2 D 3 and Suramin for HCC by Enhancing M2 Macrophage Polarization
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Anti-inflammatory effects and molecular mechanisms of bioactive small molecule garlic polysaccharide
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
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