Huidan Zhang
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Researcher
Also affiliated: Hebei University of Engineering (2020); Qingdao University (2017); Jiangnan University (2012–2013); Guangzhou University of Chinese Medicine (2019–2024); Massachusetts Eye and Ear Infirmary (2025); Ministry of Education of the People's Republic of China (2015–2025); Harvard University (2014–2025); Nanjing Normal University (2018–2025); Jilin University (2020); Chinese Academy of Sciences (2017–2025); Chinese Academy of Medical Sciences & Peking Union Medical College (2025); Peking University (2011); China University of Mining and Technology (2019); Guangdong General Hospital (2020); Harvard University Press (2014–2025); Northwest University (2025); Hainan Maternal and Child Health Hospital (2019); Changchun Institute of Optics, Fine Mechanics and Physics (2021–2025); Cambridge School (2016); Nanjing Drum Tower Hospital (2023–2025); Qinghai New Energy (China) (2021); First Affiliated Hospital of Chengdu Medical College (2024); Changchun University of Chinese Medicine (2022); Huizhou Central People's Hospital (2020); Guangdong Academy of Medical Sciences (2020–2023); ARTS Group (China) (2022); Guangdong Provincial People's Hospital (2020–2023); Qingdao Institute of Bioenergy and Bioprocess Technology (2017–2025); Qingdao Center of Resource Chemistry and New Materials (2023); Qilu Hospital of Shandong University (2025); University of Chinese Academy of Sciences (2017–2023); Jinling Institute of Technology (2025); State Key Laboratory of Supramolecular Structure and Materials (2020); Southern Medical University (2020); Nanjing University (2025); South China University of Technology (2021–2022); Taiyuan University of Technology (2024); China Medical University (2011–2018)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Huidan Zhang's research investigates mechanisms of disease and potential therapeutic interventions, with a focus on sepsis and gut microbiota disturbances. Her work has explored how sepsis-induced gut dysbiosis influences the susceptibility to sepsis-associated encephalopathy in mice. Additionally, Zhang has investigated indole-3-propionic acid as a potential therapeutic agent for sepsis-related gut microbiota issues. Her research also extends to cellular pathways involved in acute kidney injury, specifically examining how a protein encoded by circular ZNF609 RNA activates the AKT/mTOR-autophagy pathway.
Further research by Zhang includes studies on microfluidics, particularly the development and future applications of droplet microfluidics. She has also contributed to the field of materials science through research on the synthesis and properties of cesium lead bromide (CsPbBr3) perovskite quantum dots, focusing on methods to achieve ultra-small size, high efficiency, and stability. Her work in biotechnology involves metabolic engineering strategies to obtain high-purity docosahexaenoic acid oil from the microalgae *Aurantiochytrium* and the biosynthesis of triacylglycerol through rational modulation of diacylglycerol acyltransferases in the same organism.
Metrics
- h-index: 31
- Publications: 117
- Citations: 3,397
Selected Publications
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Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System (2025)
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Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System (2025)
Collaboration Network
Top Collaborators
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
- Anti-inflammatory effects and molecular mechanisms of bioactive small molecule garlic polysaccharide
Showing 5 of 10 shared publications
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- Research advances on arachidonic acid production by fermentation and genetic modification of Mortierella alpina
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
Showing 5 of 9 shared publications
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- Research advances on arachidonic acid production by fermentation and genetic modification of Mortierella alpina
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
Showing 5 of 9 shared publications
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
Showing 5 of 7 shared publications
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
- A high-throughput platform enables in situ screening of fatty acid-producing strains using laser ablation electrospray ionization mass spectrometry and a Python package
Showing 5 of 6 shared publications
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
- Use of ultra high performance liquid chromatography with high resolution mass spectrometry to analyze urinary metabolome alterations following acute kidney injury in post-cardiac surgery patients
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
Showing 5 of 6 shared publications
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
- Variations of urinary N-acetyl-β-D-glucosaminidase levels and its performance in detecting acute kidney injury under different thyroid hormones levels: a prospectively recruited, observational study
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
- Variations of urinary N-acetyl-β-D-glucosaminidase levels and its performance in detecting acute kidney injury under different thyroid hormones levels: a prospectively recruited, observational study
- Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma
- Cathelicidin LL-37 promotes EMT, migration and metastasis of hepatocellular carcinoma cells in vitro and mouse model
- Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer
- Intestinal Ecology Changes in Diarrheic Père David’s Deer Revealed by Gut Microbiota and Fecal Metabolites Analysis
- LL-37 Limits the Therapeutic Efficacy of 1,25(OH) 2 D 3 and Suramin for HCC by Enhancing M2 Macrophage Polarization
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid <i>Aurantiochytrium</i> through a Combined Metabolic Engineering Strategy
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid
- Modular Metabolic Engineering of <i><i>Mortierella alpina</i></i> by the 2A Peptide Platform to Improve Arachidonic Acid Production
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- Development and Validation of a Nomogram Incorporating Colloid Osmotic Pressure for Predicting Mortality in Critically Ill Neurological Patients
- Variations of urinary N-acetyl-β-D-glucosaminidase levels and its performance in detecting acute kidney injury under different thyroid hormones levels: a prospectively recruited, observational study
- Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma
- Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer
- Intestinal Ecology Changes in Diarrheic Père David’s Deer Revealed by Gut Microbiota and Fecal Metabolites Analysis
- LL-37 Limits the Therapeutic Efficacy of 1,25(OH) 2 D 3 and Suramin for HCC by Enhancing M2 Macrophage Polarization
- Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
- Anti-inflammatory effects and molecular mechanisms of bioactive small molecule garlic polysaccharide
- A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway
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