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Presence Current · Arkansas
Last published 2022
Sources OpenAlex · ORCID
Refreshed 2026-08-18

J. Leung

Researcher

Graduate Student Researcher

1 pubs

Biography and Research Information

OverviewAI-generated summary

J. Leung's research focuses on molecular mechanisms underlying cancer radioresistance and DNA damage response pathways. Recent work includes the discovery of a novel driver of radioresistance in pancreatic cancer, identified through genome-wide RNA sequencing. This research contributes to understanding disease mechanisms at a molecular level.

Leung has served as Principal Investigator (PI) on multiple NIH-funded grants totaling over $430,000. These grants support studies on the chromatin-based DNA damage response pathway and the mechanistic characterization of cell cycle-dependent DNA repair. Additionally, Leung is a Co-Principal Investigator on an NIH/NIEHS grant investigating RNA modifications by paternal exposure to arsenic and their intergenerational effects on sperm quality, receiving $468,131.

Collaborations include work with Adam R. Wolfe, Alan J. Tackett, Stephanie D. Byrum, and Fen Xia at the University of Arkansas for Medical Sciences, with shared publications indicating active research partnerships. Leung maintains an active lab website.

Metrics

  • Publications: 1

Selected Publications

  • Discovery of a Novel Driver of Radioresistance in Pancreatic Cancer (PC) Using Genome-Wide RNA-Seq (2022)
    International Journal of Radiation Oncology*Biology*Physics DOI OpenAlex

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Federal Grants 3 $900,659 total

NIH Co-PI Apr 2022 - Jan 2027

RNA modifications by paternal exposure to arsenic and intergenerational effects on sperm quality

National Institute of Environmental Health Sciences $468,131 R01
NIH Contact PI Mar 2021 - Dec 2022

Mechanistic characterization of the cell cycle-dependent DNA repair pathway- Resubmission

National Cancer Institute $52,528 R01
NIH Contact PI Sep 2020 - Aug 2025

Deciphering the chromatin-based DNA damage response pathway

National Institute of General Medical Sciences $380,000 R35

Collaboration Network

5 Collaborators 1 Institution 1 Country

Top Collaborators

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