H
Heba Allam Institution-verified
Sourced from institutional research profiles (UAMS TRI or ARA).
Assistant Professor
faculty
7 h-index
26 pubs
312 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Heba Allam's research investigates molecular mechanisms underlying cancer progression and treatment response. Her work focuses on the role of Glycogen Synthase Kinase-3β (GSK3β) in DNA repair pathways and its impact on tumor sensitivity to PARP1 inhibition. She has published on GSK3β's regulation of 53BP1 function in response to genotoxic stress and its influence on cancer cell survival. Additionally, her research explores the function of Sirtuin 2 (SIRT2) in maintaining stem cell resilience, particularly in the context of radiation-induced damage in oral mucositis, by promoting DNA double-strand break repair. Allam's scholarly output includes 27 publications with 308 citations and an h-index of 7. She collaborates with researchers at the University of Arkansas for Medical Sciences, including Mousumi Patra and Ratan Sadhukhan.
Metrics
- h-index: 7
- Publications: 26
- Citations: 312
Selected Publications
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SIRT2 mitigates radiation-induced oral mucositis by promoting homologous recombination-mediated DNA double-strand break repair in epithelial stem cells (2026)
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GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1 (2025)
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Sirt2 Mitigates Radiation-Induced Oral Mucositis by Promoting Homologous Recombination-Mediated DNA Double-Strand Break Repair in Epithelial Stem Cells (2025)
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376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma (2024)
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Abstract PR011: Novel role of glycogen synthase kinase-3β in determining cancer cell response to PARPi through regulation of 53BP1 function (2024)
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Novel Role of Glycogen Synthase Kinase-3β in Determining Cancer Cell Response to Genotoxic Stress through Regulation of 53BP1 Function (2023)
Grants & Funding
Collaboration Network
Top Collaborators
Mousumi Patra
University of Arkansas for Medical Sciences
6 shared publications
In database
- Novel Role of Glycogen Synthase Kinase-3β in Determining Cancer Cell Response to Genotoxic Stress through Regulation of 53BP1 Function
- Abstract PR011: Novel role of glycogen synthase kinase-3β in determining cancer cell response to PARPi through regulation of 53BP1 function
- 376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
- Sirt2 Mitigates Radiation-Induced Oral Mucositis by Promoting Homologous Recombination-Mediated DNA Double-Strand Break Repair in Epithelial Stem Cells
- The Role of SIRT2 in Oral Stem Cell Resilience in Radiation Mucositis
Showing 5 of 6 shared publications
Fen Xia
University of Arkansas for Medical Sciences
4 shared publications
In database
- Abstract PR011: Novel role of glycogen synthase kinase-3β in determining cancer cell response to PARPi through regulation of 53BP1 function
- 376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
- Sirt2 Mitigates Radiation-Induced Oral Mucositis by Promoting Homologous Recombination-Mediated DNA Double-Strand Break Repair in Epithelial Stem Cells
- GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1
Ratan Sadhukhan
University of Arkansas for Medical Sciences
4 shared publications
In database
- 376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
- Sirt2 Mitigates Radiation-Induced Oral Mucositis by Promoting Homologous Recombination-Mediated DNA Double-Strand Break Repair in Epithelial Stem Cells
- The Role of SIRT2 in Oral Stem Cell Resilience in Radiation Mucositis
- GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1
Scarlett Acklin
Duke University (US)
2 shared publications
- Novel Role of Glycogen Synthase Kinase-3β in Determining Cancer Cell Response to Genotoxic Stress through Regulation of 53BP1 Function
- Abstract PR011: Novel role of glycogen synthase kinase-3β in determining cancer cell response to PARPi through regulation of 53BP1 function
R. Kiss
University of Arkansas for Medical Sciences (US)
1 shared publication
- Novel Role of Glycogen Synthase Kinase-3β in Determining Cancer Cell Response to Genotoxic Stress through Regulation of 53BP1 Function
Jacqueline Y. K. Leung
University of Arkansas for Medical Sciences (US)
1 shared publication
- Novel Role of Glycogen Synthase Kinase-3β in Determining Cancer Cell Response to Genotoxic Stress through Regulation of 53BP1 Function
Xia Fang
University of Arkansas for Medical Sciences (US)
1 shared publication
- Novel Role of Glycogen Synthase Kinase-3β in Determining Cancer Cell Response to Genotoxic Stress through Regulation of 53BP1 Function
Kirk L. West
University of Arkansas for Medical Sciences
1 shared publication
In database
- Abstract PR011: Novel role of glycogen synthase kinase-3β in determining cancer cell response to PARPi through regulation of 53BP1 function
Justin Leung
1 shared publication
- Abstract PR011: Novel role of glycogen synthase kinase-3β in determining cancer cell response to PARPi through regulation of 53BP1 function
Jessica L Kelliher
University of Arkansas for Medical Sciences (US)
1 shared publication
- 376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
Yong‐Chen Lu
University of Arkansas for Medical Sciences
1 shared publication
In database
- 376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
Brian Koss
University of Arkansas for Medical Sciences
1 shared publication
In database
- 376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
Ali Essa
King Faisal University (SA)
1 shared publication
- Gastroesophageal Reflux Disease Among Undergraduate Medical Students in Egypt: Prevalence and Risk Factors
Ahmed Nasser
Menoufia University (EG)
1 shared publication
- Gastroesophageal Reflux Disease Among Undergraduate Medical Students in Egypt: Prevalence and Risk Factors
Ibrahim Mohamed Noureldeen
Menoufia University (EG)
1 shared publication
- Gastroesophageal Reflux Disease Among Undergraduate Medical Students in Egypt: Prevalence and Risk Factors
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