Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
Jawahar Lal Mehta
Federal Grant PI
High Impact
Distingusihed Professor
Also affiliated: United States Department of Veterans Affairs (1990–1998); UF Health Shands Hospital (2015); University of Arizona (2021); University of Georgia (1987); University of Arkansas Medical Center (2020–2026); Veterans Health Administration (1990–2021); University of Florida Health (1981–2015); University of Florida (1981–2015); Central Arkansas Veterans Healthcare System (2003–2025); North Florida/South Georgia Veterans Health System (1994–1998); John L. McClellan Memorial Veterans Hospital (2024)
Internal Med, College of Medicine
33 h-index
122 pubs
6,515 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Jawahar Lal Mehta, Distinguished Professor in Internal Medicine at the University of Arkansas for Medical Sciences College of Medicine, investigates cardiovascular disease mechanisms, focusing on the role of LOX-1 in atherogenesis. His research has been supported by federal grants, including an NIH award where he served as PI for work on PCSK9 as a novel target for myocardial ischemia treatment. Mehta has published extensively on topics related to cardiovascular health, oxidative stress, and metabolic syndrome, with his work appearing in numerous peer-reviewed journals. His scholarship metrics include an h-index of 33, with over 6,600 citations across 117 publications, indicating a significant research impact. He leads a research group and collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Nishank Jain and Subhi J. Al’Aref, with whom he has co-authored multiple publications.
Mehta is recognized as a high-impact researcher, evidenced by his highly cited status. His recent publications include contributions to guidelines for monitoring autophagy, reflecting a broader engagement with fundamental biological processes. He has also published on trends in infective endocarditis and the role of specific cellular receptors in disease contexts. His work on deletion of LOX-1 in LDLR knockout mice demonstrates a focus on animal models to elucidate disease pathways.
Metrics
- h-index: 33
- Publications: 122
- Citations: 6,515
Positions
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Distingusihed Professor 2000–presentUniversity of Arkansas System ORCID
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VA Senior Clinician-scientist 1977–presentVeterans Health Administration Medicine ORCID
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Distingusihed Professor publications 2002–2026University of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
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Associate Editor 2021–2025OAE Publishing Inc. Editorial Board ORCID
Selected Publications
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Mid‐ and Long‐Term Risk of Venous Thromboembolism Among Female Breast Cancer Survivors: A Nationwide Cohort Study (2026)
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Evaluation of Incomplete Stent Apposition of Flow Diverters at the Aneurysm Neck on Aneurysm Healing and Endothelialization: An OCT- and Histopathology-Based Study (2026)
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Time-Dependent Association Between Breast Cancer and Risk of Ischemic Stroke (2026)
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D101-04 Lox-1 Promotes Lung Homeostasis and Repair via Neutrophils in a Pathogen-Dependent Manner (2026)
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Disulfidptosis: A novel cell death mechanism with pathological significance and therapeutic potential in diseases (2026)
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Knowledge gaps in revascularization strategies in the setting of type II myocardial infarction: A common clinical dilemma in contemporary practices (2026)
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Functional Biochemistry of Iron and Its Cardiopulmonary Impact (2026)
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Remodelling-derived pre-β1 and remnant HDL particles: a snapshot of reverse cholesterol transport dynamics and efficiency (2025)
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LOX-1+ Neutrophils Exhibit a Distinct Phenotype Associated With Prevention of Lung Injury During Pneumonia (2025)
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Molecular Insights into Ischemia–Reperfusion Injury in Coronary Artery Disease: Mechanisms and Therapeutic Implications: A Comprehensive Review (2025)
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Addressing myocardial infarction in South-Asian populations: risk factors and machine learning approaches (2025)
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The pleiotropic effects of PCSK9 in cardiovascular diseases beyond cholesterol metabolism (2025)
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Reply (2024)
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Applications of ChatGPT in Heart Failure Prevention, Diagnosis, Management, and Research: A Narrative Review (2024)
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Positive Implications of Introducing Mindfulness Techniques as a Platform for Preoperative Stress Reduction to Improve Patient Outcomes Postpercutaneous Coronary Intervention (2024)
Federal Grants 1
VA
Contact PI
Oct 2009 - Aug 2022
PCSK9-A novel target for the treatment of myocardial ischemia
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Anti-myeloma efficacy of FAP inhibitor in ex vivo and in vivo systems for primary myeloma Vantia Therapeutics Ltd. Principal Investigator
- Structure based drug design for atherosclerosis targeted at LOX-1, a receptor for oxidized low-density lipoprotein American Heart Association (SouthWest Affiliate) Co-Investigator
- Regulation of LOX-1 Expression by Pioglitazone Takeda Principal Investigator
- TOPCAT: Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone AnTagonist NIH/Nat. Heart, Lung & Blood Institute via New England Research Insts., Inc. Principal Investigator
Collaboration Network
Top Collaborators
Xianwei Wang
First Affiliated Hospital of Xinxiang Medical University (CN)
27 shared publications
- Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients
- Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases
- Inflammation, Autophagy, and Apoptosis After Myocardial Infarction
- Cross-talk between LOX-1 and PCSK9 in vascular tissues
- Hemodynamic Shear Stress <i>via</i> ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta
Showing 5 of 27 shared publications
Zufeng Ding
University of Arkansas for Medical Sciences (US)
22 shared publications
- PCSK9 and inflammation: role of shear stress, pro-inflammatory cytokines, and LOX-1
- Inflammation, Autophagy, and Apoptosis After Myocardial Infarction
- Cross-talk between LOX-1 and PCSK9 in vascular tissues
- Hemodynamic Shear Stress <i>via</i> ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta
- Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis
Showing 5 of 22 shared publications
Giuseppe Calcaterra
University of Palermo (IT)
13 shared publications
- <scp>COVID</scp>‐19, thromboembolic risk, and Virchow's triad: Lesson from the past
- Cerebral Venous Sinus Thrombosis following COVID-19 Vaccination: Analysis of 552 Worldwide Cases
- COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis
- ‘Exerkines’: A Comprehensive Term for the Factors Produced in Response to Exercise
- Insights on Kawasaki disease and multisystem inflammatory syndrome: relationship with COVID-19 infection
Showing 5 of 13 shared publications
Naga Venkata K. Pothineni
University of Arkansas for Medical Sciences (US)
12 shared publications
- Oxidative Stress in Atherosclerosis
- Metabolic syndrome: pathophysiology, management, and modulation by natural compounds
- PCSK9 and inflammation: role of shear stress, pro-inflammatory cytokines, and LOX-1
- Infections, atherosclerosis, and coronary heart disease
- Inflammation and Atherosclerosis—Revisited
Showing 5 of 12 shared publications
Vignesh Chidambaram
John H. Stroger, Jr. Hospital of Cook County (US)
12 shared publications
- Association of Lipid Levels With COVID-19 Infection, Disease Severity and Mortality: A Systematic Review and Meta-Analysis
- HDL cholesterol levels and susceptibility to COVID-19
- COVID-19 in the Initiation and Progression of Atherosclerosis
- Vegetarianism, microbiota, and cardiovascular health: looking back, and forward
- Persistent cardiac injury – An important component of long COVID-19 syndrome
Showing 5 of 12 shared publications
Amudha Kumar
Loyola University Medical Center (US)
12 shared publications
- Association of Lipid Levels With COVID-19 Infection, Disease Severity and Mortality: A Systematic Review and Meta-Analysis
- HDL cholesterol levels and susceptibility to COVID-19
- COVID-19 in the Initiation and Progression of Atherosclerosis
- Vegetarianism, microbiota, and cardiovascular health: looking back, and forward
- Persistent cardiac injury – An important component of long COVID-19 syndrome
Showing 5 of 12 shared publications
Francesco Romeo
University of Rome Tor Vergata (IT)
11 shared publications
- Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): A critical player in the development of atherosclerosis and related disorders
- Infections, atherosclerosis, and coronary heart disease
- Inflammation and Atherosclerosis—Revisited
- In Vivo and In Vitro Studies Support That a New Splicing Isoform of <i>OLR1</i> Gene Is Protective Against Acute Myocardial Infarction
- Inhibition of LOX-1 by Statins May Relate to Upregulation of eNOS
Showing 5 of 11 shared publications
Tatsuya Sawamura
Shinshu University (JP)
11 shared publications
- Deletion of LOX-1 Reduces Atherogenesis in LDLR Knockout Mice Fed High Cholesterol Diet
- Cross-talk between LOX-1 and PCSK9 in vascular tissues
- Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction
- LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet
- Modulation of ADP-Induced Platelet Activation by Aspirin and Pravastatin: Role of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1, Nitric Oxide, Oxidative Stress, and Inside-Out Integrin Signaling
Showing 5 of 11 shared publications
Pier Paolo Bassareo
Mater Misericordiae University Hospital (IE)
11 shared publications
- <scp>COVID</scp>‐19, thromboembolic risk, and Virchow's triad: Lesson from the past
- Cerebral Venous Sinus Thrombosis following COVID-19 Vaccination: Analysis of 552 Worldwide Cases
- COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis
- Insights on Kawasaki disease and multisystem inflammatory syndrome: relationship with COVID-19 infection
- Concerning the unexpected prothrombotic state following some coronavirus disease 2019 vaccines
Showing 5 of 11 shared publications
Dayuan Li
University of Chicago (US)
10 shared publications
- Role of Caspases in Ox-LDL–Induced Apoptotic Cascade in Human Coronary Artery Endothelial Cells
- Molecular Imaging of Atherosclerotic Plaques Targeted to Oxidized LDL Receptor LOX-1 by SPECT/CT and Magnetic Resonance
- Pioglitazone Inhibits LOX-1 Expression in Human Coronary Artery Endothelial Cells by Reducing Intracellular Superoxide Radical Generation
- Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction
- TGF-β<sub>1</sub>attenuates myocardial ischemia-reperfusion injury via inhibition of upregulation of MMP-1
Showing 5 of 10 shared publications
Rajshekhar A. Kore
University of Arkansas for Medical Sciences
10 shared publications
In database
- NLRP3 inflammasome <i>via</i> IL-1β regulates PCSK9 secretion
- MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
- Updates on New Therapies for Patients with CKD
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Mesenchymal Stem Cell Treatment for Hyperactive Immune Response in Patients with COVID-19
Showing 5 of 10 shared publications
Abhishek Deshmukh
Central Arkansas Veterans Healthcare System (US)
8 shared publications
- Trends in Infective Endocarditis Incidence, Microbiology, and Valve Replacement in the United States From 2000 to 2011
- Prevalence of Takotsubo cardiomyopathy in the United States
- Contemporary Trends of Hospitalization for Atrial Fibrillation in the United States, 2000 Through 2010
- Inflammation and Atherosclerosis—Revisited
- Oxidized Low-Density Lipoprotein and Atherosclerosis Implications in Antioxidant Therapy
Showing 5 of 8 shared publications
Yubo Fan
Beijing Advanced Sciences and Innovation Center (CN)
8 shared publications
- Cross-talk between LOX-1 and PCSK9 in vascular tissues
- Hemodynamic Shear Stress <i>via</i> ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta
- PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy
- PCSK9 regulates expression of scavenger receptors and ox-LDL uptake in macrophages
- LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis
Showing 5 of 8 shared publications
Subhi J. Al’Aref
8 shared publications
In database
- Effect of sodium-glucose cotransporter 2 inhibitors on cardiovascular and kidney outcomes—Systematic review and meta-analysis of randomized placebo-controlled trials
- Efficacy and safety of sodium-glucose cotransporter 2 inhibitors initiation in patients with acute heart failure, with and without type 2 diabetes: a systematic review and meta-analysis
- HDL cholesterol levels and susceptibility to COVID-19
- COVID-19 in the Initiation and Progression of Atherosclerosis
- Applications of ChatGPT in Heart Failure Prevention, Diagnosis, Management, and Research: A Narrative Review
Showing 5 of 8 shared publications
Nishank Jain
University of Arkansas for Medical Sciences
8 shared publications
In database
- Updates on New Therapies for Patients with CKD
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Comparative Effectiveness and Safety of Oral P2Y12 Inhibitors in Patients on Chronic Dialysis
- Potent Antiplatelet Therapy May Reduce Death from Sepsis in Patients on Chronic Dialysis
- Renal Biomarkers in Heart Failure
Showing 5 of 8 shared publications
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