Jennifer Yanhua Xie
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Associate Professor
Also affiliated: Boston Children's Hospital (2014); Northwell Health (2024); Harvard University (2014); University of Arizona (2005–2020); University of New England (2015); New York Institute of Technology (2018–2024); Arkansas Biosciences Institute (2020); University of Arizona Cancer Center (2015); University of Arizona College of Medicine- Phoenix (2014)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jennifer Yanhua Xie's research focuses on the neurobiological mechanisms of pain and pain relief, particularly investigating the roles of reward circuitry and endogenous opioid systems. Her work has explored how pain relief can act as a negative reinforcer by engaging mesolimbic reward pathways. Xie has also examined the involvement of specific brain regions, such as the rostral ventromedial medulla and the anterior cingulate cortex, in mediating pain states, opioid-induced hyperalgesia, and antinociceptive tolerance.
Her investigations have delved into the function of various molecular targets, including adenosine A3 receptors, in alleviating persistent pain. Additionally, her research has contributed to the development of biomaterials for in vivo neurotransmitter detection, indicating an interest in analytical techniques applicable to neuroscience research. Xie's scholarly output includes 57 publications with over 3,100 citations, and she holds an h-index of 29. She has served as PI on a National Science Foundation grant totaling $719,800 for the acquisition of analytical instrumentation.
Xie collaborates with researchers at Arkansas State University, including Krishna Deo Sharma, Guo-Lei Zhou, and Regina K. Fleming, with whom she has co-authored multiple publications. She maintains an active laboratory website and is recognized as a highly cited researcher.
Metrics
- h-index: 29
- Publications: 57
- Citations: 3,159
Positions
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Associate Professor 2021–presentNYIT College of Osteopathic Medicine at Arkansas State University Basic Sciences ORCID
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Associate Professor publications 2018–2024Arkansas State University ORCID
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Assistant Professor 2017–2021New York Institute of Technology College of Osteopathic Medicine at Arkansas State University Basic Sciences ORCID
Selected Publications
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Potential mechanisms for osteopathic manipulative treatment to alleviate migraine-like pain in female rats (2024)
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Meta-epidemiologic review: Blinding and sham treatment in clinical trial design for osteopathic manipulative treatment research (2023)
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Microglial inflammation modulates opioid analgesic tolerance (2023)
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CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells (2023)
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Letters to the editor: Nicotinic acetylcholine receptor ligands as potential targets for managing neuropathic pain induced by diabetic peripheral neuropathy (2022)
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Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes (2022)
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Functionalized Nanocellulose Drives Neural Stem Cells toward Neuronal Differentiation (2021)
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Chronicling changes in the somatosensory neurons after peripheral nerve injury (2020)
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Predominant differentiation of rat fetal neural stem cells into functional oligodendrocytes in vitro (2020)
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Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes (2020)
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Antihyperalgesic effects of Meteorin in the rat chronic constriction injury model: a replication study (2019)
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Inhibition of experimental visceral pain in rodents by cebranopadol (2018)
Federal Grants 1 $719,800 total
Collaboration Network
Top Collaborators
- Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes
- CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells
- Functionalized Nanocellulose Drives Neural Stem Cells toward Neuronal Differentiation
- Predominant differentiation of rat fetal neural stem cells into functional oligodendrocytes in vitro
- Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes
Showing 5 of 6 shared publications
- Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes
- Functionalized Nanocellulose Drives Neural Stem Cells toward Neuronal Differentiation
- Predominant differentiation of rat fetal neural stem cells into functional oligodendrocytes in vitro
- Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes
- Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes
- Functionalized Nanocellulose Drives Neural Stem Cells toward Neuronal Differentiation
- Predominant differentiation of rat fetal neural stem cells into functional oligodendrocytes in vitro
- Chronicling changes in the somatosensory neurons after peripheral nerve injury
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes
- Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes
- CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells
- Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes
- Meta-epidemiologic review: Blinding and sham treatment in clinical trial design for osteopathic manipulative treatment research
- Potential mechanisms for osteopathic manipulative treatment to alleviate migraine-like pain in female rats
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Antihyperalgesic effects of Meteorin in the rat chronic constriction injury model: a replication study
- Antihyperalgesic effects of Meteorin in the rat chronic constriction injury model: a replication study
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