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Jia Liu Institution-verified

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Federal Grant PI

Associate Professor

Last refreshed 2026-05-23

faculty

Microbiology & Immunology, College of Medicine

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Biography and Research Information

OverviewAI-generated summary

Jia Liu's research program investigates mechanisms by which viruses, specifically poxviruses, interact with and evade host immune responses. As a principal investigator at the University of Arkansas for Medical Sciences, Liu has received federal funding from the National Institutes of Health/National Institute of Allergy and Infectious Diseases for two projects focused on these interactions. The first project, funded at $372,718, studies how poxviruses evade the SAMD9 pathway, a critical host defense mechanism. The second project, funded at $221,105, explores the role of APOBEC3 proteins, host factors that promote viral diversification to overcome immune restriction by poxviruses.

Liu's work aims to elucidate the molecular strategies employed by poxviruses to establish infection and replicate within a host despite the presence of antiviral defenses. Understanding these viral evasion tactics is crucial for developing effective countermeasures against viral diseases. His laboratory also maintains an active website to share research updates and findings.

Federal Grants 2 $593,823 total

NIH/National Institute of Allergy and Infectious Diseases Contact PI May 2025 - Apr 2027

APOBEC3-driven host mechanism promotes poxvirus diversification to overcome host immune restriction

National Institute of Allergy and Infectious Diseases $221,105 R21
NIH/National Institute of Allergy and Infectious Diseases Contact PI Jan 2019 - Dec 2025

Studies in Poxvirus Evasion of SAMD9 Pathway

National Institute of Allergy and Infectious Diseases $372,718 R01

Grants & Funding

  • APOBEC3-driven host mechanism promotes poxvirus diversification to overcome host immune restriction NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
  • Center for Microbial Pathogenesis and Host Inflammatory Responses NIH Co-Investigator
  • Microbiology Liu Start-up Account UAMS College of Medicine Principal Investigator
  • APOBEC3-driven host mechanism promotes poxvirus diversification to overcome host immune restriction NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
  • No FP attached UAMS College of Medicine Principal Investigator
  • No FP attached UAMS College of Medicine Principal Investigator
  • Characterization of Antiviral Functions of Sterile Alpha Motif-Containing Domain NIH Principal Investigator
  • APOBEC3-driven host mechanism promotes poxvirus diversification to overcome host immune restriction NIH Principal Investigator

Frequent Collaborators

Cannon, Martin

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