Biography and Research Information
OverviewAI-generated summary
Jason Liem investigates host-pathogen interactions, specifically focusing on poxviruses and their mechanisms of immune evasion. His research examines how viruses, such as myxoma virus, manipulate host cellular pathways to facilitate replication and avoid detection. Recent work has explored the role of specific viral proteins, like the M062 protein, in stimulating host immune responses, including the cGAS-dependent type 1 interferon pathway in human monocytes and macrophages. Liem also studies how myxoma virus antagonizes host pathways, such as the SAMD9 pathway, to achieve immune evasion and host shut-off. His work contributes to understanding viral pathogenesis and the intricate interplay between viruses and their hosts. Liem has published seven papers and holds an h-index of 4, with collaborations including Erich A. Peterson, Martin J. Cannon, Bernice Nounamo, and Richard Connor at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 4
- Publications: 7
- Citations: 120
Selected Publications
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Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion (2024)
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Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention (2023)
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Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages (2022)
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Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages (2022)
Collaboration Network
Top Collaborators
Erich A. Peterson
Winthrop Rockefeller Foundation (US)
4 shared publications
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Jia Liu
University of Arkansas for Medical Sciences (US)
3 shared publications
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion
Steven J. Conrad
University of Arkansas for Medical Sciences (US)
2 shared publications
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
Richard Connor
University of Arkansas for Medical Sciences
2 shared publications
In database
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
Bernice Nounamo
University of Arkansas for Medical Sciences
2 shared publications
In database
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
Martin J. Cannon
University of Arkansas for Medical Sciences
2 shared publications
In database
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
Tahseen Raza
University of Arkansas for Medical Sciences
2 shared publications
In database
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion
Ik Jae Shin
Winthrop Rockefeller Foundation (US)
1 shared publication
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Matthew A. Steliga
Winthrop Rockefeller Foundation
1 shared publication
In database
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Jason Muesse
Winthrop Rockefeller Foundation
1 shared publication
In database
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Katy Marino
University of Arkansas for Medical Sciences
1 shared publication
In database
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Yan Wang
University of Arkansas for Medical Sciences (US)
1 shared publication
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Kamal Pandey
University of Arkansas for Medical Sciences (US)
1 shared publication
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Ping Li
University of Arkansas for Medical Sciences (US)
1 shared publication
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
Shijie Liu
University of Arkansas for Medical Sciences (US)
1 shared publication
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
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