Jason Liem
Researcher
Also affiliated: Winthrop Rockefeller Foundation (2018–2024)
Unknown Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jason Liem investigates host-pathogen interactions, specifically focusing on poxviruses and their mechanisms of immune evasion. His research examines how viruses, such as myxoma virus, manipulate host cellular pathways to facilitate replication and avoid detection. Recent work has explored the role of specific viral proteins, like the M062 protein, in stimulating host immune responses, including the cGAS-dependent type 1 interferon pathway in human monocytes and macrophages. Liem also studies how myxoma virus antagonizes host pathways, such as the SAMD9 pathway, to achieve immune evasion and host shut-off. His work contributes to understanding viral pathogenesis and the intricate interplay between viruses and their hosts. Liem has published seven papers and holds an h-index of 4, with collaborations including Erich A. Peterson, Martin J. Cannon, Bernice Nounamo, and Richard Connor at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 4
- Publications: 7
- Citations: 122
Selected Publications
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Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion (2024)
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Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention (2023)
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Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages (2022)
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Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages (2022)
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Liquid biopsy and its role in an advanced clinical trial for lung cancer (2018)
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Myxoma Virus Optimizes Cisplatin for the Treatment of Ovarian Cancer In Vitro and in a Syngeneic Murine Dissemination Model (2017)
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Stress Beyond Translation: Poxviruses and More (2016)
Collaboration Network
Top Collaborators
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages
- Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages
- Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
- Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention
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