Match tier Listed
Presence Current · Arkansas
Last published 2024
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Jason Liem

Researcher

Also affiliated: Winthrop Rockefeller Foundation (2018–2024)

Unknown Researcher

4 h-index 7 pubs 122 cited

  • Humans
  • Poxviridae
  • Animals
  • Transcription, Genetic
  • Protein Biosynthesis
  • Virus Replication
  • Host-Pathogen Interactions
  • Interferon Type I
  • Myxoma virus
  • Poxviridae Infections
  • Clinical Decision-Making
  • Cell-Free Nucleic Acids
  • Liquid Biopsy
  • DNA, Neoplasm
  • Genotype

Biography and Research Information

OverviewAI-generated summary

Jason Liem investigates host-pathogen interactions, specifically focusing on poxviruses and their mechanisms of immune evasion. His research examines how viruses, such as myxoma virus, manipulate host cellular pathways to facilitate replication and avoid detection. Recent work has explored the role of specific viral proteins, like the M062 protein, in stimulating host immune responses, including the cGAS-dependent type 1 interferon pathway in human monocytes and macrophages. Liem also studies how myxoma virus antagonizes host pathways, such as the SAMD9 pathway, to achieve immune evasion and host shut-off. His work contributes to understanding viral pathogenesis and the intricate interplay between viruses and their hosts. Liem has published seven papers and holds an h-index of 4, with collaborations including Erich A. Peterson, Martin J. Cannon, Bernice Nounamo, and Richard Connor at the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 4
  • Publications: 7
  • Citations: 122

Selected Publications

  • Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion (2024)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention (2023)
    Elsevier eBooks DOI OpenAlex
  • Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages (2022)
    PLoS Pathogens 15 citations DOI OpenAlex
  • Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human macrophages (2022)
    bioRxiv (Cold Spring Harbor Laboratory) 4 citations DOI OpenAlex
  • Liquid biopsy and its role in an advanced clinical trial for lung cancer (2018)
    Experimental Biology and Medicine 51 citations DOI OpenAlex
  • Myxoma Virus Optimizes Cisplatin for the Treatment of Ovarian Cancer In Vitro and in a Syngeneic Murine Dissemination Model (2017)
    Molecular Therapy — Oncolytics 30 citations DOI OpenAlex
  • Stress Beyond Translation: Poxviruses and More (2016)
    Viruses 21 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

16 Collaborators 2 Institutions 1 Country

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics