Jianfeng Xu Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Researcher

Arkansas State University

faculty

35 h-index 221 pubs 4,645 cited

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Biography and Research Information

OverviewAI-generated summary

Jianfeng Xu's research focuses on harnessing biological systems, particularly plant cells, for therapeutic protein production and environmental remediation. He has received federal funding for projects investigating the engineering of plant cells to produce novel designer biologics for treating ulcerative colitis and for enhancing the production of GPI-anchored proteins. Additionally, he was a co-PI on an NSF grant for the acquisition of an X-ray Diffractometer to support materials and biomaterials research.

His recent publications explore diverse areas including the induction of apoptosis in triple-negative breast cancer cells by compounds from peanuts, the use of plants for producing therapeutic proteins and antiviral compounds against COVID-19, and the role of specific proteins in cancer cell adhesion. Other work includes the phytoremediation of cadmium pollution, the effects of melatonin and salicylic acid on postharvest fruit senescence, and the development of fluorescent sensors to visualize heavy metal stress in plants.

Xu's scholarship metrics include an h-index of 35, 135 total publications, and 4,645 total citations. He has served as PI on three federal grant awards totaling over $1.4 million and collaborates with researchers at Arkansas State University, including Paula Perez Sanchez and Jacqueline Vargas Ulloa.

Metrics

  • h-index: 35
  • Publications: 221
  • Citations: 4,645

Selected Publications

  • Advances in promoter engineering strategies for enhanced recombinant protein expression in plants (2026) DOI
  • Morphology and bioproduction potential of DCB-induced cell wall-deficient tobacco BY-2 cells and transcriptomic analysis (2025) DOI
  • Unlocking the full potential of plant cell-based production for valuable proteins: Challenges and innovative strategies (2025) DOI
  • Acidothermus cellulolyticus E1 endoglucanase expressed in planta undergoes extensive hydroxyproline-O-glycosylation and exhibits enhanced impact on biomass digestibility (2024) DOI
  • Abstract 2377 Thermophilic E1 endoglucanase from Acidothermus cellulolyticus undergoes extensive hydroxyproline-O-glycosylation when expressed in planta (2024) DOI
  • Harnessing the Power of Plants: A Green Factory for Bioactive Compounds (2023) DOI
  • Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis (2023) DOI
  • Arabinogalactan Structures of Repetitive Serine-Hydroxyproline Glycomodule Expressed by Arabidopsis Cell Suspension Cultures (2023) DOI
  • Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19 (2023) DOI
  • CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells (2023) DOI

Federal Grants 3 $1,403,716 total

NIH/National Institute of Diabetes and Digestive and Kidney Diseases Contact PI Sep 2021 - Jun 2025

Engineering novel designer biologics in plant cells for oral treatment of ulcerative colitis

National Institute of Diabetes and Digestive and Kidney Diseases $395,242 R15
NSF PI

Engineering GPI-anchored Proteins in Plant Cells for Enhanced Protein Production and Applications

Systems and Synthetic Biology, Cellular & Biochem Engineering $394,063

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