J
Jianfeng Xu Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
High Impact
Researcher
faculty
35 h-index
221 pubs
4,699 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Jianfeng Xu's research focuses on leveraging plant cells for the production of therapeutic proteins and investigating molecular mechanisms in cancer. He has received federal funding for projects related to engineering plant cells to produce novel designer biologics for the oral treatment of ulcerative colitis, and for enhancing protein production and applications through GPI-anchored proteins in plant cells. Additionally, he is a Co-PI on a grant for acquiring an X-Ray Diffractometer to support materials and biomaterials research and education.
His recent publications explore diverse areas including the cellular engineering of plants for improved therapeutic protein production, the role of Apolipoprotein L3 in enhancing CD8+ T cell antitumor immunity in colorectal cancer by promoting ferroptosis, and the regulation of epithelial-mesenchymal transition by HERC3 in colorectal cancer metastasis. Other publications address gut microbiota signatures in colorectal cancer patients, HER2 positivity as a prognostic biomarker, and radiomics-based fusion models for predicting treatment response in colorectal cancer liver metastases.
Xu holds a high-impact researcher designation, evidenced by his h-index of 35 and over 4,600 citations across 135 publications. His collaborations within Arkansas State University include shared publications with Paula PerezSanchez, Jacqueline Vargas Ulloa, Auburn Ramsey, and Jennifer Y. Xie. He maintains an active laboratory website.
Metrics
- h-index: 35
- Publications: 221
- Citations: 4,699
Selected Publications
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Advances in promoter engineering strategies for enhanced recombinant protein expression in plants (2026)
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Morphology and bioproduction potential of DCB-induced cell wall-deficient tobacco BY-2 cells and transcriptomic analysis (2025)
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Unlocking the full potential of plant cell-based production for valuable proteins: Challenges and innovative strategies (2025)
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Acidothermus cellulolyticus E1 endoglucanase expressed in planta undergoes extensive hydroxyproline-O-glycosylation and exhibits enhanced impact on biomass digestibility (2024)
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Abstract 2377 Thermophilic E1 endoglucanase from Acidothermus cellulolyticus undergoes extensive hydroxyproline-O-glycosylation when expressed in planta (2024)
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Harnessing the Power of Plants: A Green Factory for Bioactive Compounds (2023)
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Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis (2023)
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Arabinogalactan Structures of Repetitive Serine-Hydroxyproline Glycomodule Expressed by Arabidopsis Cell Suspension Cultures (2023)
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Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19 (2023)
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CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells (2023)
Federal Grants 3 $1,403,716 total
NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Contact PI
Sep 2021 - Jun 2025
Engineering novel designer biologics in plant cells for oral treatment of ulcerative colitis
NSF
Co-PI
Sep 2024 - Aug 2027
NSF
PI
Jul 2024 - Jun 2027
Engineering GPI-anchored Proteins in Plant Cells for Enhanced Protein Production and Applications
Collaboration Network
Top Collaborators
Uddhab Karki
Arkansas Biosciences Institute (US)
5 shared publications
- Cellular engineering of plant cells for improved therapeutic protein production
- Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19
- High yield secretion of human erythropoietin from tobacco cells for ex vivo differentiation of hematopoietic stem cells towards red blood cells
- Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis
- Morphology and bioproduction potential of DCB-induced cell wall-deficient tobacco BY-2 cells and transcriptomic analysis
Paula PerezSanchez
Arkansas State University
3 shared publications
In database
- Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19
- Unlocking the full potential of plant cell-based production for valuable proteins: Challenges and innovative strategies
- Acidothermus cellulolyticus E1 endoglucanase expressed in planta undergoes extensive hydroxyproline-O-glycosylation and exhibits enhanced impact on biomass digestibility
Berry Dickey
Arkansas State University (US)
3 shared publications
- Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis
- Acidothermus cellulolyticus E1 endoglucanase expressed in planta undergoes extensive hydroxyproline-O-glycosylation and exhibits enhanced impact on biomass digestibility
- Abstract 2377 Thermophilic E1 endoglucanase from Acidothermus cellulolyticus undergoes extensive hydroxyproline-O-glycosylation when expressed in planta
Haixia Zhang
Ministry of Industry and Information Technology (CN)
3 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- MAPK and hormone signaling and carotenoid biosynthesis pathways are involved in regulating flower opening of pear tree by response to temperature mediated by melatonin
- A Global Identification of Protein Disulfide Isomerases from ‘duli’ Pear (Pyrus betulaefolia) and Their Expression Profiles under Salt Stress
Yuxing Zhang
Hebei Agricultural University (CN)
3 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- PbARP1 enhances salt tolerance of ‘Duli’ pear (Pyrus betulifolia Bunge) through abscisic acid signalling pathway
- Corrigendum to “PbARP1 enhances salt tolerance of ‘Duli’ pear (Pyrus betulifolia Bunge) through abscisic acid signalling pathway” [Plant Physiology and Biochemistry 227 (2025) 110075]
Hong Fang
Arkansas State University (US)
2 shared publications
- Cellular engineering of plant cells for improved therapeutic protein production
- Acidothermus cellulolyticus E1 endoglucanase expressed in planta undergoes extensive hydroxyproline-O-glycosylation and exhibits enhanced impact on biomass digestibility
Baoxiu Qi
Liverpool John Moores University (GB)
2 shared publications
- Genome-Wide Identification of Genes Encoding for Rho-Related Proteins in ‘Duli’ Pear (Pyrus betulifolia Bunge) and Their Expression Analysis in Response to Abiotic Stress
- A Global Identification of Protein Disulfide Isomerases from ‘duli’ Pear (Pyrus betulaefolia) and Their Expression Profiles under Salt Stress
Jacqueline Vargas Ulloa
Arkansas State University
2 shared publications
In database
- Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis
- Acidothermus cellulolyticus E1 endoglucanase expressed in planta undergoes extensive hydroxyproline-O-glycosylation and exhibits enhanced impact on biomass digestibility
Peixuan Xu
Hebei Agricultural University (CN)
2 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- MAPK and hormone signaling and carotenoid biosynthesis pathways are involved in regulating flower opening of pear tree by response to temperature mediated by melatonin
Xu Wang
Hebei Agricultural University (CN)
2 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- MAPK and hormone signaling and carotenoid biosynthesis pathways are involved in regulating flower opening of pear tree by response to temperature mediated by melatonin
Shichao Luo
Hebei Agricultural University (CN)
2 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- MAPK and hormone signaling and carotenoid biosynthesis pathways are involved in regulating flower opening of pear tree by response to temperature mediated by melatonin
Ao Cheng
Hebei Agricultural University (CN)
2 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- MAPK and hormone signaling and carotenoid biosynthesis pathways are involved in regulating flower opening of pear tree by response to temperature mediated by melatonin
Hui Ma
Ministry of Industry and Information Technology (CN)
2 shared publications
- Relationships between melatonin and salicylic acid treatments in delaying the senescence of postharvest pear fruit
- MAPK and hormone signaling and carotenoid biosynthesis pathways are involved in regulating flower opening of pear tree by response to temperature mediated by melatonin
Shekoofeh Sadravi
Arkansas Biosciences Institute
2 shared publications
In database
- Unlocking the full potential of plant cell-based production for valuable proteins: Challenges and innovative strategies
- Morphology and bioproduction potential of DCB-induced cell wall-deficient tobacco BY-2 cells and transcriptomic analysis
Rui Liu
Hebei Agricultural University (CN)
2 shared publications
- PbARP1 enhances salt tolerance of ‘Duli’ pear (Pyrus betulifolia Bunge) through abscisic acid signalling pathway
- Corrigendum to “PbARP1 enhances salt tolerance of ‘Duli’ pear (Pyrus betulifolia Bunge) through abscisic acid signalling pathway” [Plant Physiology and Biochemistry 227 (2025) 110075]
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