John J. Chelonis
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
Also affiliated: United States Department of Health and Human Services (2016); Arkansas Children's Hospital (1998–2018); United States Food and Drug Administration (2019–2025); State University of New York (1992–1998); Mayo Clinic (2018); School of the Art Institute of Chicago (2018); Government of the United States of America (2023); York University (2006–2007); Economie Publique (2018); Food and Drug Administration (2018–2019); Conway School of Landscape Design (2003); Arkansas Department of Agriculture (2002); SUNY Brockport (2006–2011); Stony Brook University (1992–1997); University of Missouri (1992–1999)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
John J. Chelonis' research focuses on the long-term effects of prenatal exposure to trace elements and environmental factors on child development and behavior. His work investigates the associations between prenatal exposure to mixtures of metals, such as lead and manganese, and developmental outcomes, including learning deficits, altered time perception, and reward motivation in children. Chelonis has examined these relationships using behavioral acquisition tasks and operant test batteries, with a particular interest in how these effects may be modified by factors such as child sex and socioeconomic status.
His research also extends to animal models, specifically rhesus monkeys, to study the effects of long-term methylphenidate administration and withdrawal on behavioral responding and neuroimaging outcomes. This comparative approach aims to understand the underlying mechanisms of developmental neurotoxicity and the impact of environmental exposures on neurobehavioral development. Chelonis collaborates with researchers at the National Center for Toxicological Research, including Merle G. Paule, John Talpos, Serguei Liachenko, and Natalya Sadovova, on these studies.
With an h-index of 24 and over 2,400 citations across 69 publications, Chelonis is recognized as a highly cited researcher. His recent publications address topics such as prenatal exposure mixtures and learning deficits, prenatal metal concentrations and reward motivation, and the sexually dimorphic effects of prenatal lead exposure on behavioral performance in children.
Metrics
- h-index: 24
- Publications: 69
- Citations: 2,442
Selected Publications
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Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children (2025)
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Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach (2025)
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Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex (2023)
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The effects of long-term methylphenidate administration and withdrawal on progressive ratio responding and T2 MRI in the male rhesus monkey (2022)
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Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children (2022)
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Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children (2022)
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Prenatal metal mixture concentrations and reward motivation in children (2021)
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Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City (2021)
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The application of statistical models to create meaningful psychological endpoints for environmental exposures: Generating forgetting functions in children exposed to lead (2020)
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Acetyl-l-carnitine does not prevent neurodegeneration in a rodent model of prolonged neonatal anesthesia (2020)
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Performance on the Operant Test Battery in young children exposed to procedures requiring general anaesthesia: the MASK study (2019)
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List of Contributors (2018)
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Sevoflurane exposure has minimal effect on cognitive function and does not alter microglial activation in adult monkeys (2018)
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Early life exposure to extended general anesthesia with isoflurane and nitrous oxide reduces responsivity on a cognitive test battery in the nonhuman primate (2018)
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Determining the Validity of Preclinical Behavioral Assessments for Extrapolation to a Clinical Setting (2018)
Collaboration Network
Top Collaborators
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Prenatal metal mixture concentrations and reward motivation in children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
Showing 5 of 7 shared publications
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Prenatal metal mixture concentrations and reward motivation in children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
Showing 5 of 7 shared publications
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Prenatal metal mixture concentrations and reward motivation in children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
Showing 5 of 7 shared publications
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Prenatal metal mixture concentrations and reward motivation in children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- The effects of long-term methylphenidate administration and withdrawal on progressive ratio responding and T2 MRI in the male rhesus monkey
- Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Prenatal metal mixture concentrations and reward motivation in children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex
- Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City
- Prenatal metal mixture concentrations and reward motivation in children
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
- Prenatal metal mixture concentrations and reward motivation in children
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children
- Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex
- Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach
- Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City
- Prenatal metal mixture concentrations and reward motivation in children
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