John J. Chelonis

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

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NCTR primary UA Little Rock University of Central Arkansas UAMS

Also affiliated: United States Department of Health and Human Services (2016); Arkansas Children's Hospital (1998–2018); United States Food and Drug Administration (2010–2025); State University of New York (1994–2007); Mayo Clinic (2018); Baylor College of Medicine (2018); University of Arkansas System (2002); Government of the United States of America (2023); SUNY Brockport (2006–2011); Stony Brook University (1992–1998); University of Missouri (1992–1999)

24 h-index 69 pubs 2,480 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

John J. Chelonis' research focuses on the long-term effects of prenatal exposure to trace elements and environmental factors on child development and behavior. His work investigates the associations between prenatal exposure to mixtures of metals, such as lead and manganese, and developmental outcomes, including learning deficits, altered time perception, and reward motivation in children. Chelonis has examined these relationships using behavioral acquisition tasks and operant test batteries, with a particular interest in how these effects may be modified by factors such as child sex and socioeconomic status.

His research also extends to animal models, specifically rhesus monkeys, to study the effects of long-term methylphenidate administration and withdrawal on behavioral responding and neuroimaging outcomes. This comparative approach aims to understand the underlying mechanisms of developmental neurotoxicity and the impact of environmental exposures on neurobehavioral development. Chelonis collaborates with researchers at the National Center for Toxicological Research, including Merle G. Paule, John Talpos, Serguei Liachenko, and Natalya Sadovova, on these studies.

With an h-index of 24 and over 2,400 citations across 69 publications, Chelonis is recognized as a highly cited researcher. His recent publications address topics such as prenatal exposure mixtures and learning deficits, prenatal metal concentrations and reward motivation, and the sexually dimorphic effects of prenatal lead exposure on behavioral performance in children.

Metrics

h-index: 24
Publications: 69
Citations: 2,480

Selected Publications

Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children (2025)

Science Advances 4 citations DOI OpenAlex
Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach (2025)

Children DOI OpenAlex
Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex (2023)

Environmental Research 7 citations DOI OpenAlex
The effects of long-term methylphenidate administration and withdrawal on progressive ratio responding and T2 MRI in the male rhesus monkey (2022)

Neurotoxicology and Teratology 2 citations DOI OpenAlex
Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children (2022)

New Directions for Child and Adolescent Development 17 citations DOI OpenAlex
Sexually dimorphic associations between prenatal blood lead exposure and performance on a behavioral testing battery in children (2022)

Neurotoxicology and Teratology 13 citations DOI OpenAlex
Prenatal metal mixture concentrations and reward motivation in children (2021)

NeuroToxicology 15 citations DOI OpenAlex
Sexually dimorphic associations between prenatal blood lead exposure and temporal processing in 6- to 7-year-old children in Mexico City (2021)

ISEE Conference Abstracts DOI OpenAlex
The application of statistical models to create meaningful psychological endpoints for environmental exposures: Generating forgetting functions in children exposed to lead (2020)

ISEE Conference Abstracts DOI OpenAlex
Acetyl-l-carnitine does not prevent neurodegeneration in a rodent model of prolonged neonatal anesthesia (2020)

Neurotoxicology and Teratology 6 citations DOI OpenAlex
Performance on the Operant Test Battery in young children exposed to procedures requiring general anaesthesia: the MASK study (2019)

British Journal of Anaesthesia 31 citations DOI OpenAlex
List of Contributors (2018)

Elsevier eBooks DOI OpenAlex
Sevoflurane exposure has minimal effect on cognitive function and does not alter microglial activation in adult monkeys (2018)

NeuroToxicology 21 citations DOI OpenAlex
Early life exposure to extended general anesthesia with isoflurane and nitrous oxide reduces responsivity on a cognitive test battery in the nonhuman primate (2018)

NeuroToxicology 41 citations DOI OpenAlex
Determining the Validity of Preclinical Behavioral Assessments for Extrapolation to a Clinical Setting (2018)

Elsevier eBooks DOI OpenAlex