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Presence Current · Arkansas
Last published 2020
Sources OpenAlex · ORCID
Refreshed 2026-10-04

Jungang Chen

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Also affiliated: Winthrop Rockefeller Foundation (2020)

2 h-index 2 pubs 20 cited

  • Sarcoma, Kaposi
  • Herpesvirus 8, Human
  • Humans
  • Nuclear Proteins
  • Transcription Factors
  • Protein Serine-Threonine Kinases
  • Endothelial Cells
  • Interleukin-1
  • Signal Transduction
  • Bromodomain Containing Proteins
  • Proteolysis Targeting Chimera
  • Antigens, Viral
  • Protein Biosynthesis
  • Cell Cycle Proteins
  • Cell Proliferation

Biography and Research Information

OverviewAI-generated summary

Jungang Chen's research investigates the pathogenesis of Kaposi's Sarcoma-associated Herpesvirus (KSHV) and explores potential therapeutic targets. His work focuses on the role of Interleukin-1 family members and their signaling pathways in KSHV infection. Chen has also studied the impact of targeting specific proteins, such as BRD2 and BRD4, to inhibit the growth of KSHV-infected endothelial cells by suppressing LANA translation. Additionally, his research includes investigating the resistance mechanisms of primary effusion lymphoma cells to rapamycin and exploring the targeting of sphingosine kinase as a potential treatment for diffuse intrinsic pontine glioma. Chen has co-authored publications with collaborators Lu Dai and Zhiqiang Qin from the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 2
  • Publications: 2
  • Citations: 20

Selected Publications

  • Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation (2026)
    PLoS Pathogens DOI OpenAlex
  • Targeting Hyaluronan Signaling Overcomes Primary Effusion Lymphoma Cells Resistance to Rapamycin (2026)
    Biological Procedures Online DOI OpenAlex
  • Oral Microbiota: Findings, Classification, Clinical Significance, and Therapeutic Interventions for Human Systemic Diseases (2026)
    iMetaMed 1 citation DOI OpenAlex
  • Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis (2020)
    Frontiers in Cellular and Infection Microbiology 12 citations DOI OpenAlex
  • Targeting Sphingosine Kinase by ABC294640 against Diffuse Intrinsic Pontine Glioma (DIPG) (2020)
    Journal of Cancer 8 citations DOI OpenAlex

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Collaboration Network

27 Collaborators 19 Institutions 5 Countries

Top Collaborators

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