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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
L
Lawrence E. Cornett
Federal Grant PI
High Impact
Distinguished Professor
Also affiliated: Baptist Memorial Hospital (1982); Arkansas Children's Hospital (1997); United States Department of Veterans Affairs (1983); University of California, San Francisco (1980–1981); University of Washington (1983–1985); University of Arkansas Medical Center (1987–2008); Veterans Health Administration (1983); John L. McClellan Memorial Veterans Hospital (1990–1995); University of California, Davis (1977–1979)
24 h-index
89 pubs
1,626 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Lawrence E. Cornett's research has focused on the characterization and functional analysis of peptide receptors and their signaling pathways, particularly within the context of vasopressin and related neuropeptides. His work has involved molecular cloning and the functional characterization of receptor subtypes, such as a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken, identified as the avian homolog of the mammalian V1b-vasopressin receptor. Cornett has also investigated the interactions between different receptor types, including heterooligomerization between vasotocin and corticotropin-releasing hormone (CRH) receptors, and its effect on cellular signaling pathways like cyclic adenosine monophosphate (cAMP) production.
His earlier research explored the binding characteristics of arginine-vasopressin in rat kidney and brain tissues, and the identification of proteins involved in the acrosome reaction of spermatozoa. Further investigations have examined plasma levels of neuropeptides in chickens and their interaction with myometrial binding sites. Cornett's work has also extended to adrenergic receptors, including the characterization of alpha 1-adrenergic receptor subtypes in smooth muscle cell lines. He leads a research group and has received significant federal funding for his research endeavors, with a notable grant from the NIH/National Institute of General Medical Sciences. His scholarship metrics indicate a highly cited researcher with 87 publications and over 1,600 citations.
Metrics
- h-index: 24
- Publications: 89
- Citations: 1,626
Positions
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Distinguished Professor 1980–presentUniversity of Arkansas for Medical Sciences Physiology and Cell Biology Institutional directory
Selected Publications
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An IDeA for increasing biomedical research capacity (2026)
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Corrigendum to “Social processes, practical issues, and COVID-19 vaccination among hesitant adults” [Vaccine 41(35) (2023) 5150–5158]. (2025)
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Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents (2025)
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Identifying and training deep learning neural networks on biomedical-related datasets (2024)
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Using focused ethnography to inform biomedical research infrastructure enhancement at primarily undergraduate institutions (2023)
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COVID-19 Booster Uptake: Are Hesitant Adopters Less Likely to Get a Booster Shot Than Nonhesitant Adopters? (2023)
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Social processes, practical issues, and COVID-19 vaccination among hesitant adults (2023)
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Development of a clinical and translational research curriculum for undergraduate students (2023)
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Impact of the INBRE summer student mentored research program on undergraduate students in Arkansas (2018)
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A possible mechanism contributing to the synergistic action of vasotocin (VT) and corticotropin-releasing hormone (CRH) receptors on corticosterone release in birds (2013)
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Effects of the β‐agonist, isoprenaline, on the down‐regulation, functional responsiveness and trafficking of β2‐adrenergic receptors with N‐terminal polymorphisms (2012)
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Distribution of the Vasotocin Subtype Four Receptor ( VT 4 R ) in the Anterior Pituitary Gland of the Chicken, G allus gallus, and its Possible Role in the Avian Stress Response (2012)
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Age-dependent expression of AVT and its oxytocic-like receptor VT3 in the shell gland of Japanese quail, Coturnix coturnix japonica (2009)
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Corticosterone- or metapyrone-induced alterations in adrenal function and expression of the arginine vasotocin receptor VT2 in the pituitary gland of domestic fowl, Gallus gallus (2009)
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Transmembrane domain IV of the Gallus gallus VT[sub 2] vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor (2008)
Federal Grants 1 $4,037,901 total
NIH
Contact PI
Sep 2001 - Apr 2031
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- ASTA Support for INBRE Arkansas Science & Technology Authority
- Partnerships for Biomedical Research in Arkansas - 1-Year with costs Extension NIH/Nat. Inst. of General Medical Sciences
- Cloning and Functional Characterization of an Avian Pituitary Gland Vasotocin Receptor National Science Foundation
- Neuroendocrine Control of Shell Gland Contractility in the Domestic Hen US Department of Agriculture
- BIOCHEMICAL STUDIES OF VASOPRESSIN RECEPTORS NIH
- Partnerships for Biomedical Research in Arkansas - Admin Supplement NIH/Nat. Inst. of General Medical Sciences
- ADRENERGIC RECEPTORS IN A SMOOTH MUSCLE CELL LINE NIH
Collaboration Network
Top Collaborators
Chandra Mohini Chaturvedi
University of Arkansas for Medical Sciences (US)
12 shared publications
- Molecular cloning of an oxytocin-like receptor expressed in the chicken shell gland
- An in situ hybridization and immunohistochemical study of vasotocin neurons in the hypothalamus of water-deprived chickens
- A Sexual Dimorphism in Hypothalamic Arginine Vasotocin (AVT) Gene Expression and AVT Plasma Levels in the Japanese Quail (Coturnix coturnix japonica) in Response to Water Deprivation
- Arginine Vasotocin Gene Expression in Hypothalamic Neurons is Up-Regulated in Chickens Drinking Hypertonic Saline: An In Situ Hybridization Study
- Effect of photoperiod and estrogen on expression of arginine vasotocin and its oxytocic-like receptor in the shell gland of the Japanese quail
Showing 5 of 12 shared publications
James S. Norris
University of Arkansas for Medical Sciences (US)
9 shared publications
- Characterization of the alpha 1-adrenergic receptor subtype in a smooth muscle cell line.
- Specific binding sites for prohormone atrial natriuretic peptides 1–30, 31–67 and 99–126
- Autocrine regulation of growth: II. Glucocorticoids inhibit transcription of c-sis oncogene-specific RNA transcripts
- Characteristics of an Adenylate Cyclase Coupled β-Adrenergic Receptor in a Smooth Muscle Tumor Cell Line
- Blockade of alpha-adrenergic receptors by analogues of phosphatidylcholine
Showing 5 of 9 shared publications
Stacie M. Jones
Arkansas Children's Hospital
9 shared publications
In database
- Molecular Cloning and Functional Characterization of a Vasotocin Receptor Subtype That Is Expressed in the Shell Gland and Brain of the Domestic Chicken1
- Molecular cloning and functional characterization of a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken (Gallus domesticus): avian homolog of the mammalian V1b-vasopressin receptor
- Effects of the β‐agonist, isoprenaline, on the down‐regulation, functional responsiveness and trafficking of β2‐adrenergic receptors with N‐terminal polymorphisms
- Enhanced β2-adrenergic receptor (β2AR) signaling by adeno-associated viral (AAV)-mediated gene transfer
- Characterization of a panel of six β2-adrenergic receptor antibodies by indirect immunofluorescence microscopy
Showing 5 of 9 shared publications
T.I. Koike
In-Q-Tel (US)
9 shared publications
- Plasma levels of immunoreactive mesotocin and vasotocin during oviposition in chickens: Relationship to oxytocic action of the peptides in vitro and peptide interaction with myometrial membrane binding sites
- An in situ hybridization and immunohistochemical study of vasotocin neurons in the hypothalamus of water-deprived chickens
- Arginine Vasotocin Gene Expression and Secretion during Osmotic Stimulation and Hemorrhagic Hypotension in Hens
- A Sexual Dimorphism in Hypothalamic Arginine Vasotocin (AVT) Gene Expression and AVT Plasma Levels in the Japanese Quail (Coturnix coturnix japonica) in Response to Water Deprivation
- Arginine Vasotocin Gene Expression in Hypothalamic Neurons is Up-Regulated in Chickens Drinking Hypertonic Saline: An In Situ Hybridization Study
Showing 5 of 9 shared publications
Dennis A. Baeyens
University of Arkansas at Little Rock (US)
7 shared publications
- Molecular Cloning and Functional Characterization of a Vasotocin Receptor Subtype That Is Expressed in the Shell Gland and Brain of the Domestic Chicken1
- Molecular cloning and functional characterization of a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken (Gallus domesticus): avian homolog of the mammalian V1b-vasopressin receptor
- The cloned avian neurohypophysial hormone receptors
- Molecular cloning of an oxytocin-like receptor expressed in the chicken shell gland
- Transcriptional and posttranscriptional regulation of hepatic β2‐adrenergic receptor gene expression during development
Showing 5 of 7 shared publications
Wayne J. Kuenzel
University of Arkansas at Fayetteville
6 shared publications
In database
- Heterooligomerization between Vasotocin and Corticotropin-Releasing Hormone (CRH) Receptors Augments CRH-Stimulated 3′,5′-Cyclic Adenosine Monophosphate Production
- Characterization and immunohistochemical visualization of the vasotocin VT2 receptor in the pituitary gland of the chicken, Gallus gallus
- A possible mechanism contributing to the synergistic action of vasotocin (VT) and corticotropin-releasing hormone (CRH) receptors on corticosterone release in birds
- Distribution of the Vasotocin Subtype Four Receptor ( VT 4 R ) in the Anterior Pituitary Gland of the Chicken, G allus gallus, and its Possible Role in the Avian Stress Response
- Immunohistochemical characterization of chicken pituitary cells containing the vasotocin VT2 receptor
Showing 5 of 6 shared publications
Marina V. Mikhailova
University of Arkansas Medical Center (US)
5 shared publications
- Heterooligomerization between Vasotocin and Corticotropin-Releasing Hormone (CRH) Receptors Augments CRH-Stimulated 3′,5′-Cyclic Adenosine Monophosphate Production
- Molecular cloning of an oxytocin-like receptor expressed in the chicken shell gland
- Distribution of the Vasotocin Subtype Four Receptor ( VT 4 R ) in the Anterior Pituitary Gland of the Chicken, G allus gallus, and its Possible Role in the Avian Stress Response
- Transmembrane domain IV of the Gallus gallus VT[sub 2] vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor
- Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor
Sandie E. Jacobi
University of Arkansas for Medical Sciences (US)
5 shared publications
- Identification of a Glucocorticoid Response Element in the Rat β2-Adrenergic Receptor Gene
- Transmembrane domain IV of the Gallus gallus VT[sub 2] vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor
- Enhanced β2-adrenergic receptor (β2AR) signaling by adeno-associated viral (AAV)-mediated gene transfer
- Transcription of the β2-adrenergic receptor gene in rat liver is regulated during early postnatal development by an upstream repressor element
- Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor
Philip R. Mayeux
University of Arkansas for Medical Sciences
5 shared publications
In database
- Molecular Cloning and Functional Characterization of a Vasotocin Receptor Subtype That Is Expressed in the Shell Gland and Brain of the Domestic Chicken1
- Heterooligomerization between Vasotocin and Corticotropin-Releasing Hormone (CRH) Receptors Augments CRH-Stimulated 3′,5′-Cyclic Adenosine Monophosphate Production
- Molecular cloning and functional characterization of a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken (Gallus domesticus): avian homolog of the mammalian V1b-vasopressin receptor
- Transmembrane domain IV of the Gallus gallus VT[sub 2] vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor
- Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor
Richard C. Kurten
Arkansas Children's Hospital
5 shared publications
In database
- Effects of the β‐agonist, isoprenaline, on the down‐regulation, functional responsiveness and trafficking of β2‐adrenergic receptors with N‐terminal polymorphisms
- Characterization of a panel of six β2-adrenergic receptor antibodies by indirect immunofluorescence microscopy
- Ex vivo analysis of airway contraction and relaxation by a beta-agonist
- 263 EX VIVO ANALYSIS OF AIRWAY CONTRACTION AND RELAXATION BY A β-AGONIST
- Ex Vivo Analysis of Airway Contraction and Relaxation by a β-Agonist
F. Charles Hiller
University of Arkansas for Medical Sciences (US)
4 shared publications
- Identification of a Glucocorticoid Response Element in the Rat β2-Adrenergic Receptor Gene
- Regulation of the β2-Adrenergic Receptor and its Mrna in the Rat Lung by Dexamethasone
- Enhanced β2-adrenergic receptor (β2AR) signaling by adeno-associated viral (AAV)-mediated gene transfer
- Structural and functional analysis of the 5′-flanking region of the rat β2-adrenergic receptor gene
Alexander Jurkevich
University of Arkansas at Fayetteville (US)
4 shared publications
- Heterooligomerization between Vasotocin and Corticotropin-Releasing Hormone (CRH) Receptors Augments CRH-Stimulated 3′,5′-Cyclic Adenosine Monophosphate Production
- Distribution of the Vasotocin Subtype Four Receptor ( VT 4 R ) in the Anterior Pituitary Gland of the Chicken, G allus gallus, and its Possible Role in the Avian Stress Response
- Immunohistochemical characterization of chicken pituitary cells containing the vasotocin VT2 receptor
- Identification of the vasotocin VT2 receptors in the pituitary gland and their implication in the functions of the HPA axis of chickens
Bradley J. Schnackenberg
Arkansas Children's Hospital (US)
4 shared publications
- Characterization of a panel of six β2-adrenergic receptor antibodies by indirect immunofluorescence microscopy
- Ex vivo analysis of airway contraction and relaxation by a beta-agonist
- 263 EX VIVO ANALYSIS OF AIRWAY CONTRACTION AND RELAXATION BY A β-AGONIST
- Ex Vivo Analysis of Airway Contraction and Relaxation by a β-Agonist
Dennis W. McGraw
University of Arkansas for Medical Sciences (US)
4 shared publications
- Identification of a Glucocorticoid Response Element in the Rat β2-Adrenergic Receptor Gene
- Regulation of the β2-Adrenergic Receptor and its Mrna in the Rat Lung by Dexamethasone
- Structural and functional analysis of the 5′-flanking region of the rat β2-adrenergic receptor gene
- Transcription of the β2-adrenergic receptor gene in rat liver is regulated during early postnatal development by an upstream repressor element
Don E. Willis
University of Arkansas for Medical Sciences
4 shared publications
In database
- Social processes, practical issues, and COVID-19 vaccination among hesitant adults
- COVID-19 Booster Uptake: Are Hesitant Adopters Less Likely to Get a Booster Shot Than Nonhesitant Adopters?
- Vaccine hesitancy or hesitancies? A latent class analysis of pediatric patients' parents
- Corrigendum to “Social processes, practical issues, and COVID-19 vaccination among hesitant adults” [Vaccine 41(35) (2023) 5150–5158].
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