Maha Hanafi

Researcher

University of Arkansas for Medical Sciences

unknown

3 h-index 5 pubs 85 cited

Research Areas

Pancreatic and Hepatic Oncology Research Cancer Treatment and Pharmacology Protein Degradation and Inhibitors Computational Drug Discovery Methods Cancer-related molecular mechanisms research

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OverviewAI-generated summary

Maha Hanafi's research focuses on the development of novel therapeutic strategies, particularly for pancreatic cancer. Her work has involved the design and synthesis of orally active quinolyl pyrazinamides as sigma 2 receptor ligands, aiming to provide new treatment options for this disease. Additionally, she has investigated the discovery of PROTACs (proteolysis-targeting chimeras) as a method to degrade specific E3 ligases, such as ZFP91, which may have implications for cancer therapy. Her recent publications also include a patent review of rearranged during transfection (RET) kinase inhibitors and the exploration of the copper-KRAS-COX2 axis as a therapeutic vulnerability in pancreatic cancer. Hanafi's scholarship metrics include an h-index of 3, with 5 total publications and 85 total citations.

Metrics

  • h-index: 3
  • Publications: 5
  • Citations: 85

Selected Publications

  • An updated patent review of rearranged during transfection (RET) kinase inhibitors (2022-present) (2025) DOI

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