Match tier Likely match
Presence Current · Arkansas
Last published 2023
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Meenakshi Upreti

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

Also affiliated: University of Kentucky (2012–2017); Jawaharlal Nehru University (2004–2005); Albert B. Chandler Hospital (2016); Markey Cancer Center (2016–2017)

Faculty Researcher

18 h-index 45 pubs 1,026 cited

  • Humans
  • Animals
  • Cell Line, Tumor
  • Mice
  • Gene Expression Profiling
  • Apoptosis
  • Vinblastine
  • Female
  • bcl-X Protein
  • Cell Survival
  • Algorithms
  • Endothelial Cells
  • Interferon Regulatory Factor-1
  • Signal Transduction
  • Models, Biological

Biography and Research Information

OverviewAI-generated summary

Meenakshi Upreti's research focuses on the molecular mechanisms of apoptosis, particularly in response to chemotherapeutic agents. Her work investigates the role of key proteins, such as Bak and Bax, in initiating programmed cell death. Upreti has published research on the activation of Bak and its interaction with Bax in the apoptotic response to vinblastine, a common chemotherapy drug. This research utilizes cell lines and animal models to understand cellular survival and death pathways. Upreti has a publication record of 45 papers, with over 1,000 citations, and an h-index of 18, indicating a consistent output of scholarly work in her field. She has collaborated with researchers Elena Galitovskaya and Timothy C. Chambers at the University of Arkansas for Medical Sciences on multiple publications.

Metrics

  • h-index: 18
  • Publications: 45
  • Citations: 1,026

Selected Publications

  • Data from Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine (2023)
  • Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells (2012)
    Cancer Research DOI OpenAlex
  • Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth (2012)
    Cancer Research DOI OpenAlex
  • Vascular Disrupting Agent Arsenic Trioxide Enhances Thermoradiotherapy of Solid Tumors (2012)
    Journal of Oncology 12 citations DOI OpenAlex
  • Abstract 5288: Tumor-endothelial 3D spheroids for dynamic imaging of cancer progression (2011)
    Cancer Research 1 citation DOI OpenAlex
  • Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics (2011)
    Translational Oncology 80 citations DOI OpenAlex
  • ChemInform Abstract: Synthesis and Anticancer Activity of Sclerophytin‐Inspired Hydroisobenzofurans. (2010)
    ChemInform DOI OpenAlex
  • Inferring Functional Relationships and Causal Network Structure from Gene Expression Profiles (2010)
    Methods in enzymology on CD-ROM/Methods in enzymology 1 citation DOI OpenAlex
  • Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling (2010)
    Cell Death and Disease 17 citations DOI OpenAlex
  • Granger Causality Analysis of Human Cell-Cycle Gene Expression Profiles (2010)
    Statistical Applications in Genetics and Molecular Biology 18 citations DOI OpenAlex
  • Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis (2009)
    Biochemical Pharmacology 25 citations DOI OpenAlex
  • Cyclin-Dependent Kinase 1-Mediated Bcl-x<sub>L</sub>/Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis (2009)
    Molecular and Cellular Biology 210 citations DOI OpenAlex
  • Synthesis and anticancer activity of sclerophytin-inspired hydroisobenzofurans (2009)
    Bioorganic & Medicinal Chemistry Letters 23 citations DOI OpenAlex
  • Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine (2008)
    Molecular Cancer Therapeutics 42 citations DOI OpenAlex
  • Identifying Non-random Patterns from Gene Expression Profiles (2008)
    Lecture notes in computer science DOI OpenAlex

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Collaboration Network

4 Collaborators 1 Institution 1 Country

Top Collaborators

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