Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-20
M
Mohammad A. Alam
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
High Impact
Professor
Also affiliated: University of Minnesota (2011); University of Ottawa (2011); Twin Cities Orthopedics (2011); University of Minnesota, Duluth (2011–2018); Arkansas Biosciences Institute (2017–2025); Rowan University (2013–2016); Indian Institute of Technology Kanpur (2008)
Faculty Researcher
22 h-index
75 pubs
1,141 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Mohammad A. Alam's research focuses on the design, synthesis, and evaluation of novel chemical compounds, particularly pyrazole derivatives, as potential therapeutic agents. His work investigates the antibacterial properties of these compounds against a range of pathogens, including resistant strains like *Staphylococcus aureus* and *Acinetobacter baumannii*. Alam has published extensively on the structure-activity relationships of these molecules, aiming to develop potent inhibitors of bacterial processes such as fatty acid biosynthesis.
His research also extends to the broader application of privileged scaffolds like pyrazoles and thiazoles in drug discovery, exploring their utility in creating antimicrobial agents. Alam has secured significant federal funding, including grants from the NIH and NSF, to support his research endeavors. He has served as PI on projects involving functional genomics of oral pathogens and the acquisition of advanced analytical instrumentation, such as X-ray diffractometers and NMR spectrometers, to enhance research capabilities at Arkansas State University. His scholarly contributions are recognized by a high h-index of 22 and over 1,000 citations, positioning him as a highly cited researcher.
Metrics
- h-index: 22
- Publications: 75
- Citations: 1,141
Selected Publications
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Genomic instability and biofilm determinants in <i>Streptococcus mutans</i> : insights from a sequence-defined arrayed transposon library (2026)
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Genomic instability and biofilm determinants in <i>Streptococcus mutans</i> : insights from a sequence-defined arrayed transposon library (2026)
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Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives (2026)
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Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection (2026)
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High-level production of antibacterial pentacyclic triterpenoids from hairy root cultures of Bixa orellana via abiotic elicitation (2026)
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Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors (2025)
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Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures (2025)
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Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea (2025)
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Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors (2024)
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Synthesis of Thiazole‐Fused Diosgenin Derivatives as Potential Therapeutic Agents (2024)
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Editorial: Five-membered heterocycles: synthesis and applications (2024)
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Efficient Synthesis of Thiazole-Fused Bisnoralcohol Derivatives as Potential Therapeutic Agents (2024)
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Domino Reaction Protocol to Synthesize Benzothiophene-Derived Chemical Entities as Potential Therapeutic Agents (2024)
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Construction of an arrayed CRISPRi library as a resource for essential gene function studies in <i>Streptococcus mutans</i> (2023)
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Pyrazole: an Emerging Privileged Scaffold in Drug Discovery (2023)
Federal Grants 3 $1,379,507 total
NIH
Contact PI
Sep 2024 - Sep 2027
Systematic Functional Genomics Analysis of the Oral Pathogen Streptococcus Mutans
NSF
Co-PI
Sep 2024 - Aug 2027
NSF
PI
Aug 2021 - Jul 2024
Collaboration Network
Top Collaborators
Subrata Roy
Arkansas State University
9 shared publications
In database
- Design, synthesis, and antibacterial activity of<i>N</i>-(trifluoromethyl)phenyl substituted pyrazole derivatives
- Benign synthesis of fused-thiazoles with enone-based natural products and drugs for lead discovery
- Development and Antibacterial Properties of 4-[4-(Anilinomethyl)-3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors
- Synthesis of 3,5-Bis(trifluoromethyl)phenyl-Substituted Pyrazole Derivatives as Potent Growth Inhibitors of Drug-Resistant Bacteria
- Domino Reaction Protocol to Synthesize Benzothiophene-Derived Chemical Entities as Potential Therapeutic Agents
Showing 5 of 9 shared publications
David F. Gilmore
Arkansas State University
7 shared publications
In database
- Design, synthesis, and antibacterial activity of<i>N</i>-(trifluoromethyl)phenyl substituted pyrazole derivatives
- 4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents
- Synthesis of Chimeric Thiazolo‐Nootkatone Derivatives as Potent Antimicrobial Agents
- Development and Antibacterial Properties of 4-[4-(Anilinomethyl)-3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors
- Novel Pyrazoles As Potent Growth Inhibitors of Staphylococci, Enterococci and <i>Acinetobacter Baumannii</i> Bacteria
Showing 5 of 7 shared publications
Hansa Raj KC
Arkansas State University
6 shared publications
In database
- Design, synthesis, and antibacterial activity of<i>N</i>-(trifluoromethyl)phenyl substituted pyrazole derivatives
- Development and Antibacterial Properties of 4-[4-(Anilinomethyl)-3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors
- Novel Pyrazoles As Potent Growth Inhibitors of Staphylococci, Enterococci and <i>Acinetobacter Baumannii</i> Bacteria
- Development of 4-[4-(Anilinomethyl)-3-phenyl-pyrazol-1-yl] Benzoic Acid Derivatives as Potent Anti-Staphylococci and Anti-Enterococci Agents
- Synthesis of 3,5-Bis(trifluoromethyl)phenyl-Substituted Pyrazole Derivatives as Potent Growth Inhibitors of Drug-Resistant Bacteria
Showing 5 of 6 shared publications
Robert C. Shields
Arkansas State University
6 shared publications
In database
- Development and Antibacterial Properties of 4-[4-(Anilinomethyl)-3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors
- Construction of an arrayed CRISPRi library as a resource for essential gene function studies in <i>Streptococcus mutans</i>
- Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea
- Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures
- High-level production of antibacterial pentacyclic triterpenoids from hairy root cultures of Bixa orellana via abiotic elicitation
Showing 5 of 6 shared publications
Alexei G. Basnakian
Arkansas State University
5 shared publications
In database
- 4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents
- Antimelanoma activities of chimeric thiazole–androstenone derivatives
- Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection
Shailesh Budhathoki
Arkansas State University
5 shared publications
In database
- Domino Reaction Protocol to Synthesize Benzothiophene-Derived Chemical Entities as Potential Therapeutic Agents
- Synthesis of Thiazole‐Fused Diosgenin Derivatives as Potential Therapeutic Agents
- Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection
Ibrahim S. Alkhaibari
Arkansas State University (US)
4 shared publications
- Synthesis of Chimeric Thiazolo‐Nootkatone Derivatives as Potent Antimicrobial Agents
- Benign synthesis of fused-thiazoles with enone-based natural products and drugs for lead discovery
- Novel Pyrazoles As Potent Growth Inhibitors of Staphylococci, Enterococci and <i>Acinetobacter Baumannii</i> Bacteria
- Synthesis of 3,5-Bis(trifluoromethyl)phenyl-Substituted Pyrazole Derivatives as Potent Growth Inhibitors of Drug-Resistant Bacteria
Sanjay Adhikary
Arkansas State University
4 shared publications
In database
- In Vitro Antimelanoma Properties of Verbena officinalis Fractions
- Efficient Synthesis of Thiazole-Fused Bisnoralcohol Derivatives as Potential Therapeutic Agents
- Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
Gaurav Gajurel
Arkansas State University
4 shared publications
In database
- Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea
- Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures
- High-level production of antibacterial pentacyclic triterpenoids from hairy root cultures of Bixa orellana via abiotic elicitation
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection
Justin Roberts
Arkansas State University
3 shared publications
In database
- Development and Antibacterial Properties of 4-[4-(Anilinomethyl)-3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors
- Construction of an arrayed CRISPRi library as a resource for essential gene function studies in <i>Streptococcus mutans</i>
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection
Mohamed Milad
Arkansas State University
3 shared publications
In database
- Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection
Amit Raj Sharma
Arkansas State University
3 shared publications
In database
- Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea
- Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures
- High-level production of antibacterial pentacyclic triterpenoids from hairy root cultures of Bixa orellana via abiotic elicitation
Salma Abdel-Karim
Arkansas State University
3 shared publications
In database
- Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea
- Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures
- High-level production of antibacterial pentacyclic triterpenoids from hairy root cultures of Bixa orellana via abiotic elicitation
Fabricio Medina-Bolívar
Arkansas State University
3 shared publications
In database
- Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea
- Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection
Rawan Alnufaie
Arkansas State University
2 shared publications
In database
- Synthesis of Chimeric Thiazolo‐Nootkatone Derivatives as Potent Antimicrobial Agents
- Benign synthesis of fused-thiazoles with enone-based natural products and drugs for lead discovery
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