Alexei G. Basnakian Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
Arkansas State University
faculty
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Biography and Research Information
OverviewAI-generated summary
Alexei G. Basnakian's research focuses on understanding cellular and molecular mechanisms underlying various disease states, with a particular emphasis on cancer and radiation injury. His work has investigated the role of specific enzymes and signaling pathways in cellular processes such as autophagy and DNA damage response. Basnakian has explored potential therapeutic agents, including derivatives of benzoic acid and thiazole, for combating bacterial infections and melanoma. His research also extends to evaluating the safety of novel materials, such as carbon nanotubes, for agricultural applications.
Further contributions include examining the effects of gamma-tocotrienol in mitigating intestinal injury induced by radiation, both in general and in specific acute radiation syndrome models. Additionally, Basnakian has explored the potential of viruses, like Morreton virus, as platforms for oncolytic virotherapy targeting liver cancers. He has published extensively on these topics, evidenced by his h-index of 36 and over 4,000 citations. Basnakian collaborates with researchers at the University of Arkansas for Medical Sciences, including Martin J. Cannon, Steven R. Post, Camila Simões, and Mulu Z. Tesfay, with whom he has co-authored multiple publications.
Metrics
- h-index: 36
- Publications: 137
- Citations: 4,009
Selected Publications
- Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection (2026) DOI
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025) DOI
- Abstract B022: Reprogramming Apoptotic Resistance in PDAC Through Synthetic Oncolytic Immunotherapy (2025) DOI
- Pancreatic tumor microenvironment reprogramming via alloantigen-expressing virotherapy elicits tumor rejection and improves immunotherapy response (2025) DOI
- An Enhancement of Extrachromosomal Circular DNA Enrichment and Amplification to Address the Extremely Low Overlap Between Replicates (2025) DOI
- Abstract 945: Live attenuated MMR vaccines modulate tumor immune cell infiltration and synergize with standard of care to prolong survival in preclinical HCC models (2025) DOI
- Abstract 947: Engineering a synthetic oncolytic virus to overcome apoptotic resistance and induce immunogenic cell death in pancreatic ductal adenocarcinoma (2025) DOI
- Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors (2025) DOI
- The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury (2025) DOI
- Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors (2024) DOI
- Generation of BT-Amide, a Bone-Targeted Pyk2 Inhibitor, Effective <i>via</i> Oral Administration, for the Prevention of Glucocorticoid-Induced Bone Loss (2024) DOI
- Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer (2024) DOI
- Abstract 5004: Oncolytic Jurona-driven systemic and intratumoral immunotherapy combined with immune checkpoint blockade boost immune response and survival in hepatocellular carcinoma models (2024) DOI
- Endonuclease G (EndoG) Inhibits DNase I-Mediated Apoptosis and DNA Repair in Kidney Tubular Epithelial Cells During Cisplatin Injury (2023) DOI
- Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy (2022) DOI
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