Nikos Tapinos Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Director of Molecular Neuroscience and Neuro-Oncology Research / Associate Professor

John Brown University

faculty

23 h-index 105 pubs 1,838 cited

Research Areas

Glioma Diagnosis and Treatment Epigenetics and DNA Methylation RNA Research and Splicing Radiopharmaceutical Chemistry and Applications Chemical Reactions and Isotopes

Links

ORCID

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OverviewAI-generated summary

Dr. Nikos Tapinos directs Molecular Neuroscience and Neuro-Oncology Research, focusing on the diagnosis and treatment of gliomas. His work spans diverse areas, including epigenetics, DNA methylation, RNA splicing, and radiopharmaceutical chemistry. Recent investigations have explored the role of Chi3l1 as a modulator of glioma stem cell states, identifying it as a potential therapeutic target in glioblastoma. Tapinos's research also investigates lipid-based nanoparticles for cancer chemoimmunotherapy and the synergistic effects of EZH2 and HDAC inhibitors in promoting apoptosis across multiple tumor types. His work extends to understanding miRNA-mediated loss of m6A and its impact on translation in glioblastoma, as well as the efficacy of imipridone-based combination therapies in treating diffuse intrinsic pontine glioma.

His primary research interests involve glioma diagnosis and treatment.

Metrics

  • h-index: 23
  • Publications: 105
  • Citations: 1,838

Selected Publications

  • Multiomic profiling of hypoxic glioblastoma stem cells reveals expansion of subpopulations with distinct epigenetic and CNV profiles (2025) DOI
  • Review of microRNA detection workflows from liquid biopsy for disease diagnostics (2025) DOI
  • Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma (2024) DOI

Collaborators

Researchers in the database who share publications

Bedia Akosman John Brown University 23 shared publications Yusuke Suita John Brown University 8 shared publications Mattia D. Pizzagalli John Brown University 4 shared publications Adrianne Corseri John Brown University 3 shared publications Wafik S. El‐Deiry John Brown University 2 shared publications Ritambhara Singh John Brown University 2 shared publications Hye‐Yeon Hwang John Brown University 2 shared publications Attila A. Seyhan John Brown University 1 shared publication

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