Ning Wu
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Researcher
Also affiliated: Ithaka Harbors (2013); Tulane University (2017); Biogen (United States) (2016–2018); Beth Israel Deaconess Medical Center (2013); Van Andel Institute (2017–2023); Harvard University (2013); Central South University (2016–2020); Guiyang Medical University (2023); Hunan University of Traditional Chinese Medicine (2020); Shanxi Medical University (2024); Shanghai Jiao Tong University (2016); Regeneron (United States) (2020); Peking University (2025); Huazhong Agricultural University (2014–2016); Renji Hospital (2016); Academy of Military Medical Sciences (2008); United BioSource Corporation (United Kingdom) (2010–2012); Integrated Chinese Medicine (China) (2025); Hanalei Watershed Hui (2011); The People's Hospital of Guangxi Zhuang Autonomous Region (2022–2024); Chongqing University of Education (2020); Dana-Farber Cancer Institute (1984); Peking University First Hospital (2025); Shanghai University of Medicine and Health Sciences (2021–2022); Ministry of Agriculture and Rural Affairs (2014–2016); Dongfeng Motor Group (China) (2018–2020); Center for Systems Biology (2013); Xiangya Hospital Central South University (2016–2020); Shanxi Provincial People’s Hospital (2024); Health & Life (Taiwan) (2010); Institute of Pharmacology (2015–2024); Nanjing Medical University (2013–2016); Tsinghua University (2008)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Ning Wu's research investigates the physiological and pathological roles of thioredoxin interacting protein (TXNIP), focusing on its connection to redox inflammation and metabolism. Wu's work has examined how excess dietary carbohydrate intake affects mitochondrial integrity, specifically in brown adipose tissue. Further studies have explored the response of PPARγ and C/EBPα to acute cold stress in brown adipose tissue. Additionally, Wu has contributed to understanding the molecular mechanisms of TXNIP, including its interaction with GLUT1, which is dependent on PI(4,5)P2.
Beyond metabolic studies, Wu's research extends to behavioral and pharmacological investigations. This includes comparing the efficacy of cannabidiol and sertraline in modulating post-traumatic stress disorder-like behaviors and fear memory in mice. A subsequent study demonstrated that cannabidiol can ameliorate PTSD-like symptoms by inhibiting neuroinflammation via CB2 receptors in the brains of male mice. Wu has also explored the relationship between obesity-related anthropometric indicators and cognitive function in older adults and has applied AI-powered topic modeling to analyze opioid-related cardiovascular risks in women.
Metrics
- h-index: 23
- Publications: 100
- Citations: 3,021
Selected Publications
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Echo Chamber Dynamics in LLMs: Mitigating Bias and Model Drift (2026)
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AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women (2025)
Collaboration Network
Top Collaborators
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- Echo Chamber Dynamics in LLMs: Mitigating Bias and Model Drift
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