Beverly Lyn‐Cook
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Researcher
Also affiliated: University of North Carolina at Chapel Hill (1983–2008); North Carolina Central University (2004); U.S. National Science Foundation (2006); United States Food and Drug Administration (2008–2025); Missouri Department of Agriculture (2018); Office of Multidisciplinary Activities (2013); Beverly Hospital (2015); Clark Atlanta University (1984); Canisius College (1992); Western University of Health Sciences (2008)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Beverly Lyn‐Cook's research focuses on understanding disease mechanisms and health disparities, particularly concerning cancer, metabolism, and the impact of environmental exposures. Her work frequently investigates differences across demographic groups, including sex and race, and utilizes advanced computational methods for data analysis. Lyn‐Cook has published on topics such as the metabolome of breast tissues and its correlation with microbial dysbiosis and lipid metabolism in triple-negative breast tumors, and the association of tryptophan metabolism with obesity and triple-negative breast cancer risk in Black and White women.
Her research also explores the immunotoxicity of nanoparticles, examining sex-based differences in response to agents like silver nanoparticles. Additionally, she has investigated the effects of nanoparticles, such as titanium dioxide, on epigenetic modifications in human cell lines. Lyn‐Cook employs sophisticated data mining and topic modeling techniques, including AI-powered approaches like LDA and BERTopic, to analyze large datasets, such as those related to opioid adverse events and prescription opioid use literature.
Lyn‐Cook is a highly cited researcher with an h-index of 30 and over 130 publications. She leads a research group and has collaborated extensively with colleagues at the National Center for Toxicological Research, including Beverly Word, Paul Rogers, Wen Zou, and Weigong Ge.
Metrics
- h-index: 30
- Publications: 130
- Citations: 3,166
Selected Publications
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Abstract C054: Pharmacogenomics evaluation of histone deacetylase inhibitors on the treatment of triple-negative breast cancer subtypes (2025)
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AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women (2025)
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Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells (2024)
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Identifying Vulnerabilities to NSAID Adverse Events in the U.S. Population: An Analysis of Preexisting Conditions and Sex (2024)
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Abstract 4253: High expression of specific gene profiles in organoids from African American pancreatic cancer tumors (2024)
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Investigation of sex-based differences in the immunotoxicity of silver nanoparticles (2024)
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RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system (2024)
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A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database (2023)
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Identifying Vulnerabilities to NSAID Adverse Events in the US Population: An Analysis of Pre-Existing Conditions and Sex (2023)
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Epigenotoxicity of Titanium Dioxide Nanoparticles (2023)
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Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat (2023)
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Characterization of the Metabolome of Breast Tissues from Non-Hispanic Black and Non-Hispanic White Women Reveals Correlations between Microbial Dysbiosis and Enhanced Lipid Metabolism Pathways in Triple-Negative Breast Tumors (2022)
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Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines (2022)
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Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells (2022)
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Abstract 3022: Tryptophan metabolism is associated with obesity and triple negative breast cancer risk in black and white women (2022)
Collaboration Network
Top Collaborators
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
- Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells
- Abstract 995: Alpelisib and vorinostat modulate critical genes in basal-2 triple negative breast cancer cells and inhibit cell growth and invasion
- Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat
Showing 5 of 7 shared publications
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Epigenotoxicity of Titanium Dioxide Nanoparticles
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
- Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells
- Abstract 995: Alpelisib and vorinostat modulate critical genes in basal-2 triple negative breast cancer cells and inhibit cell growth and invasion
Showing 5 of 7 shared publications
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- Investigation of sex-based differences in the immunotoxicity of silver nanoparticles
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Identifying Vulnerabilities to NSAID Adverse Events in the US Population: An Analysis of Pre-Existing Conditions and Sex
Showing 5 of 6 shared publications
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells
- Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat
- Abstract 4253: High expression of specific gene profiles in organoids from African American pancreatic cancer tumors
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Epigenotoxicity of Titanium Dioxide Nanoparticles
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Epigenotoxicity of Titanium Dioxide Nanoparticles
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
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